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1 Management and grading of EGFR inhibitor-induced ...
https://www.futuremedicine.com/doi/10.2217/fon-2018-0187
Grading of toxicity ; Redness and flushing only, with or without itch, Papules, pustules and irritation (acneiform), Crusted, eroded pustular ...
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2 Clinical Guideline for the Management of Skin Toxicity ...
https://www.nhsscotlandnorth.scot/uploads/tinymce/NCA/SACT%20Guidelines/NOS-STG-006_Skin%20toxicity_version%201.pdf
This table describes the grading and management of skin rash. Drug rashes are usually mild, widespread red rashes with no other symptoms. Table 2: Skin rash ...
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3 Risk of High-Grade Skin Rash in Cancer ... - Karger Publishers
https://www.karger.com/Article/Fulltext/229752
Other options include the addition of oral doxycycline or minocycline. The EGFR inhibitor should be continued during treatment of the rash. The ...
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4 Prevention and Treatment of Acneiform Rash in Patients ...
https://www.albertahealthservices.ca/assets/info/hp/cancer/if-hp-cancer-guide-supp003-egfri-rash.pdf
because of the role of EGFR in skin biology they are associated with a variety of ... o Skin rash 56%; grades 3/4: 15-26% (combination therapy with. FOLFOX).
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5 Acneiform eruption secondary to epidermal growth factor ...
https://www.uptodate.com/contents/acneiform-eruption-secondary-to-epidermal-growth-factor-receptor-egfr-and-mek-inhibitors
Risk factors for severe rash — Potential risk factors for the development of severe EGFR inhibitor-related acneiform rash include age, sex, skin ...
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6 The challenge of managing a cetuximab rash - MDedge
https://www.mdedge.com/hematology-oncology/article/190465/patient-survivor-care/challenge-managing-cetuximab-rash
A cetuximab-induced rash is common. In a 2011 meta-analysis quantifying grades 1 to 4 in severity, about 75% of patients treated with an EGFR inhibitor ...
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7 Cetuximab (Erbitux®) | OncoLink
https://www.oncolink.org/cancer-treatment/oncolink-rx/cetuximab-erbitux-r
Use a thick, alcohol-free emollient lotion or cream on your skin at least twice a day, including right after bathing. · Sun exposure can worsen the rash. · Bathe ...
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8 Prevention and Treatment of Acneiform Rash Caused by ...
https://ascopost.com/issues/may-15-2013/prevention-and-treatment-of-acneiform-rash-caused-by-egfr-inhibitors/
Prevention of acneiform rash caused by EGFR inhibitors includes topical corticosteroids (hydrocortisone 2.5%, alclometasone) and oral ...
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9 Evaluation of a Comprehensive Skin Toxicity Program for ...
https://jamanetwork.com/journals/jamadermatology/fullarticle/2767661
At cetuximab treatment initiation, 29 patients (25%) in 2012 and 42 patients ... There was no significant difference in incidence of rash by ...
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10 Dermatologic Toxicity Occurring During Anti-EGFR ...
https://www.sciencedirect.com/science/article/pii/S153300281630278X
These toxicities can occur frequently: ∼90% of patients will experience skin toxicity of any grade during treatment with panitumumab or cetuximab monotherapy, ...
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11 Epidermal Growth Factor Receptor Inhibitors and Skin Rash
https://www.uspharmacist.com/article/epidermal-growth-factor-receptor-inhibitors-and-skin-rash
For mild rash, recommendations include topical clindamycin 1% plus a topical corticosteroid applied twice daily to affected areas until ...
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12 1241-Acneiform rash associated with EGFR inhibitors - eviQ
https://www.eviq.org.au/clinical-resources/side-effect-and-toxicity-management/hair-skin-and-nails/1241-acneiform-rash-associated-with-egfr-inhibitor
Treatment (of established disease) · moisturise the skin with an alcohol-free thick moisturising/emollient cream at least twice a day · avoid sun exposure as rash ...
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13 EGFR Treatment for mCRC & SCCHN | ERBITUX (cetuximab)
https://www.erbitux.com/treatment
Rash may be treated with antibiotics. Antibiotics may be in pill form (and may be taken by mouth) or as a skin cream. Side effects for each person may vary.
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14 Management Strategies for Cutaneous Toxicity From EGFR ...
https://voice.ons.org/news-and-views/management-strategies-for-cutaneous-toxicity-from-egfr-inhibitors
In 2009, the National Comprehensive Cancer Network developed its expert consensus on the management of skin toxicity with EGFR inhibitors.
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15 Skin Rash During Cetuximab Treatment in Advanced ...
https://link.springer.com/article/10.1007/s12029-013-9485-7
by J Giuliani · 2013 · Cited by 8 —
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16 Correlation between efficacy and skin rash occurrence ...
https://www.spandidos-publications.com/10.3892/or_00000319/download
treatment with the epidermal growth factor receptor inhibitor cetuximab: A single institution retrospective ... Cetuximab-induced skin rash was classified.
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17 Skin Toxicity Evaluation Protocol With Panitumumab (STEPP ...
https://ascopubs.org/doi/10.1200/jco.2008.21.7828
The incidence of protocol-specified ≥ grade 2 skin toxicities during the 6-week skin treatment period was 29% and 62% for the pre-emptive and ...
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18 Cutaneous Toxicity Associated With Cetuximab Treatment in ...
https://www.elsevier.es/es-revista-farmacia-hospitalaria-english-edition--221-articulo-cutaneous-toxicity-associated-with-cetuximab-S2173508511000062
Cetuximab treatment was discontinued temporarily or permanently in 9 patients (20.9%) due to adverse skin or infusion reactions. In 7 cases (16.3%), the ...
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19 ORIGINAL ARTICLE - Annals of Oncology
https://www.annalsofoncology.org/article/S0923-7534(19)45465-3/pdf
Key words: acne-like skin rash, cetuximab, colorectal cancer, ... field of skin rash is that conventional systems for grading skin.
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20 Topical aloe vera for the treatment of cetuximab-related ...
https://journals.sagepub.com/doi/abs/10.1177/1078155220937751
The most common and earliest skin toxicity is acneiform rash which affects 60 to 80% of the patients. In this case, cetuximab-related severe ...
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21 What is the role of topical creams, skin moisturisers and ...
https://wiki.cancer.org.au/australia/Clinical_question:What_is_the_role_of_topical_creams,_skin_moisturisers_and_maintenance_antibiotics_in_the_treatment_of_rash_from_anti-EGFR_therapy_in_patients_with_lung_cancer%3F
The positive association of rash with treatment responses vexes this issue. Where tumour progression has occurred on treatment the EGFR ...
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22 Skin Reactions to Targeted Therapy and Immunotherapy
https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/skin-reactions-targeted-therapy-and-immunotherapy
This means rashes and changes to the hair and nails may occur during treatment with these drugs. Most people taking drugs that target EGFR ...
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23 Oncology TV > Symptom Management > Cutaneous Toxicities
https://www.oncology.tv/SymptomManagement/CutaneousToxicities
An alternate grading scale for EGFRI-associated skin toxicity is the MASCC EGFR Inhibitor Skin Toxicity Tool (MESTT) available through the Multinational ...
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24 SKIN TOXICITY Tips for Managing Side Effects of the Skin
https://fightcolorectalcancer.org/wp-content/uploads/2019/11/SkinToxicity_MiniMag_2019_WEB.pdf
with cetuximab or panitumumab will experience it to some degree. Sometimes when the skin rash presents, it can be a sign that the treatment is working.
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25 Management of cutaneous side effects of cetuximab therapy ...
https://www.onko-i.si/fileadmin/onko/datoteke/dokumenti/RadiolOncol_42_4_7.pdf
of the skin toxicity helps patients to overcome cetuximab-associated skin ... rash. Median time for the improvement of skin rash of all grades was 18 days.
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26 Severe skin reaction secondary to concomitant radiotherapy ...
https://ro-journal.biomedcentral.com/articles/10.1186/1748-717X-3-5
Exacerbated radiation dermatitis after cetuximab treatment. ... The skin rash by EGFRI is thought to be the direct consequence of the EGFR ...
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27 Dermatologic Toxicity Occurring During Anti-EGFR ...
https://www.clinical-colorectal-cancer.com/article/S1533-0028(16)30278-X/pdf
with these anti-EGFR antibodies.21,22. Treatment with anti-EGFR agents has been associated with a number of dermatologic toxicities (including skin rash, ...
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28 Skin Rash Study Before Chemotherapy in Colorectal & Head ...
https://clinicaltrials.gov/ct2/show/NCT01874860
If they develop severe skin rash as a result of cetuximab therapy, the study ... 3 weeks into cetuximab treatment and at the end of cetuximab treatment for ...
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29 Reducing Skin Toxicities from EGFR Inhibitors with Topical ...
https://aacrjournals.org/cancerdiscovery/article/11/9/2158/666275/Reducing-Skin-Toxicities-from-EGFR-Inhibitors-with
In skin cells (B), administration of EGFR inhibitor treatment leads to decreased MAPK signaling and acneiform rash. Topical therapy with LUT014 would ...
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30 Management of skin rash during EGFR-targeted monoclonal ...
https://europepmc.org/article/med/19229368
Although EGFRIS have been proven effective in the treatment of a variety of malignancies, the entire class of agents is associated with a high prevalence of ...
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31 Prophylactic Dermatologic Treatment of Afatinib-Induced Skin ...
https://www.hindawi.com/journals/scientifica/2019/9136249/
Results. Out of 34 treated patients, the incidence of skin rash (all grades) was 41.2% and grade 2 rash was 20.6%, and grade 3 rash ...
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32 EGFR Inhibitor-induced Acneiform Rash: A Review of Current ...
https://practicaldermatology.com/articles/2013-aug/egfr-inhibitor-induced-acneiform-rash-a-review-of-current-management-strategies
› articles › 2013-aug
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33 A review of cutaneous toxicities from targeted therapies in the ...
https://jgo.amegroups.com/article/view/1285/html
The most common cutaneous toxicity resulting from treatment with EGFR inhibitors ... In the cetuximab group 156 of 197 developed an acneiform skin rash with ...
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34 Tips for Managing Treatment-Related Rash and Dry Skin
https://media.cancercare.org/publications/original/8-ccc_rash.pdf
of people with colorectal cancer who were treated with cetuximab, an EGFR inhibitor. This clinical trial showed a strong link between the development of a rash ...
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35 Predictors of Tumor Response to Cetuximab and ...
https://www.actasdermo.org/index.php?p=revista&tipo=pdf-simple&pii=S1578219015001547
get the epidermal growth factor receptor (EGFR) in the treatment of metastatic ... Summary of treatment of EGFR inhibitor---induced skin rash used at our.
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36 Papulopustular Rash | Multikinase Inhibitor Skin Toxicity
https://oncologypro.esmo.org/oncology-in-practice/palliative-and-supportive-care/multikinase-inhibitor-related-skin-toxicity/healthcare-professionals/symptoms-and-grading/skin-changes/papulopustular-rash
An alternate option for grading papulopustular rash is provided by the Multinational Association of Supportive Care in Cancer (MASCC) EGFR Inhibitor Skin ...
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37 A review of the treatment options for skin rash induced by ...
https://www.scienceopen.com/document_file/2ad555e7-6721-408d-88b0-2df8d227c7da/PubMedCentral/2ad555e7-6721-408d-88b0-2df8d227c7da.pdf
Background. Agents targeting the epidermal growth factor receptor (EGFR) are amongst the most extensively used of the targeted agents in the therapy of some ...
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38 When treatment gets under your skin…
https://archive.cancerworld.net/wp-content/uploads/2017/07/3019_CW18_14_22_grandround.pdf
this is how one patient describes the feeling when, six days into his first course of cetuximab (Erbitux), he start- ed to developed the acne-like skin rash.
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39 Latest News : Side effect of cancer treatment can be safely ...
https://cancer.ucla.edu/Home/Components/News/News/1672
Topical therapy provides protection against skin rash caused by EGFR inhibitors. Post Date:April 28, 2021 7:00 AM. FacultyAntoni Ribas, Zev Wainberg.
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40 Skin Rash could Predict the Response to EGFR Tyrosine ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055128
skin rash after EGFR-TKI treatment may be an efficient clinical marker for predicting the response of patients with NSCLC to EGFR-TKIs.
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41 Associations between skin rash, treatment outcome, and ...
https://www.tandfonline.com/doi/full/10.1080/0284186X.2018.1464664
During the first 3 weeks of treatment, 86% of the patients experienced any grade of rash and 17% experienced a moderate to severe rash. Development of moderate ...
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42 Skin Toxicity as Predictor of Survival in Refractory Patients ...
https://mdpi-res.com/d_attachment/cancers/cancers-13-05715/article_deploy/cancers-13-05715-v2.pdf?version=1637056170
of activity of cetuximab plus avelumab treatment and its correlation ... Dermatologic toxicities such as acneiform rash, dry skin, pruritus, ...
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43 A Rash of Good News - Cure Today
https://www.curetoday.com/view/a-rash-of-good-news
Side effect may predict response to treatment. ... For instance, skin rash occurs in up to 90 percent of patients treated with Erbitux, ...
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44 Skin Care During Treatment With Epidermal Growth Factor ...
https://www.mskcc.org/cancer-care/patient-education/skin-care-during-treatment-targeted-therapies
Stay out of the sun before starting treatment with EGFR inhibitors. ... You may develop dry skin with, or after the acne-like rash.
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45 World Journal of Oncology
https://www.wjon.org/index.php/wjon/article/view/1381/1059
Short title: Skin Rash in Metastatic Colorectal Cancer ... All patients with mCRC who received cetuximab treatment in combination with chemotherapy, ...
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46 Management of skin rash during EGFR- targeted monoclonal ...
https://pdfs.semanticscholar.org/b78d/d7b50d61e76b66f6b088c8f0bbb65599321a.pdf
membrane glycoprotein that is expressed in many. Management of skin rash during EGFR- targeted monoclonal antibody treatment for gastrointestinal.
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47 Side effect of cancer treatment can be safely reduced with ...
https://www.uclahealth.org/news/side-effect-of-cancer-treatment-can-be-safely-reduced-with-topical-cream
Topical therapy provides protection against skin rash caused by EGFR inhibitors. From left: Dr. Antoni Ribas, Dr. Zev Wainberg ...
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48 Treating Skin-Associated Toxicities Related to EGFR Inhibitors
https://www.cancernetwork.com/view/treating-skin-associated-toxicities-related-egfr-inhibitors
It is recommended that patients treated with EGFR inhibitors begin prophylactic rash therapy with doxycycline 100 mg twice a day or minocycline ...
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49 Oncologist®
https://www.oncodeva.net/upload/rcp/piele_cetuxi.pdf
Management of Skin Toxicity Associated with Cetuximab Treatment ... Cetuximab • EGFR • Italian Expert Opinions • Skin rash • Skin toxicity.
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50 Relationship between skin rash and outcome in non-small-cell ...
https://www.lungcancerjournal.info/article/S0169-5002(12)00390-X/abstract
These results are noteworthy, because patients with severe skin rash may be reassured over treatment outcome Skin rash during treatment with anti-EGFR TKIs ...
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51 Cetuximab Drug Monograph Update
https://www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/Cetuximab_Drug_Monograph_Update.doc
In addition, cetuximab was approved as a single agent for the treatment of ... with the exception of anti-EGFR antibody toxicities of acne-like skin rash, ...
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52 The Riddle of Cetuximab-Related Skin Toxicity: 1H-NMR - MDPI
https://www.mdpi.com/2072-6694/14/21/5308/pdf
skin rash experienced by patients. The results of this study indicate that cetuximab-based treatment can reduce sebum gland activity, ...
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53 EGFR Inhibitor–Associated Papulopustular Rash
https://jhoponline.com/jhop-issue-archive/2017-issues/jhop-march-2017-vol-7-no-1/17060-egfr-inhibitor-associated-papulopustular-rash
One of the most common classwide adverse events associated with these drugs is dermatologic toxicity. Skin reactions associated with EGFR inhibitor therapy may ...
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54 Dermatologic toxicity occurring during anti-EGFR monoclonal ...
https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=8879&context=open_access_pubs
treatment, the dermatologic toxicities associated with anti-EGFR monoclonal ... version 4.0, grades skin rash using a scale from 1 to 4.38 Grading the.
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55 Predictive blood plasma biomarkers for EGFR inhibitor ...
https://www.oncotarget.com/article/17060/text/
During an EGFRI treatment period of four weeks, 45 patients (21.3 %) developed no skin toxicity while 80 patients (37.9 %) experienced grade 1, ...
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56 Cetuximab-induced Acneiform Eruption and the Response to ...
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-0330
The therapeutic management of cetuximab-induced acne remains controversial. Some authors recently suggested that grading of acneiform rash is an essential step ...
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57 The predictive role of skin rash with cetuximab and ...
https://www.researchgate.net/publication/234141996_The_predictive_role_of_skin_rash_with_cetuximab_and_panitumumab_in_colorectal_cancer_patients_A_systematic_review_and_meta-analysis_of_published_trials
The occurrence of skin rash during treatment with cetuximab and panitumumab represents a significant predictor of the efficacy of these ...
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58 A proposed EGFR inhibitor dermatologic adverse event ...
https://oralmedicinepacific.com/docs/whats-new/EGFRi-grading-MASCC-JSCC-2010.pdf
grading scale from the MASCC skin toxicity study group ... CTCAE v4.0 rash grading were noted by the MASCC group. Whereas most drug rashes ...
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59 Cetuximab - SWAG Cancer Alliance
https://www.swagcanceralliance.nhs.uk/wp-content/uploads/2020/09/Cetuximab.v2.pdf
First line treatment of metastatic, K-RAS wild type colorectal cancer in ... Interrupt cetuximab in severe skin reactions (≥ grade 3 acneiform rash).
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60 Cetuximab (Erbitux) | Cancer information - Cancer Research UK
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/cetuximab
It stays in while you're having treatment, which may be for a few months. ... A reaction may happen during the infusion, causing a skin rash, itching, ...
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61 Prophylactic Effect of Oral Minocycline in Combination with ...
https://ar.iiarjournals.org/content/35/11/6175
Acneiform rash and other adverse events were graded according to the CTCAE v4.0. Results: The occurrence of acneiform rash (grade ≥2) was significantly lower ...
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62 Treatment of Skin Lesions Induced by Cetuximab Therapy ...
https://www.gavinpublishers.com/article/view/treatment-of-skin-lesions-induced-by-cetuximab-therapy-with-an-acid-oxidizing-solution-containing-hypochlorous-acid
Acneiform (papulopustular) rash that usually develops on the upper trunk and face 1-2 weeks after starting the treatment · Xerosis (up to 35% of patients) ...
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63 Management of Dermatologic Toxicities From Targeted Therapy
https://www.advancedpractitioner.com/media/198800/sun-4_dermatologic_lacouture_final.pdf
Acneiform Rash: EGFR inhibitors ... Prophylactic skin treatment regimen administered weeks 1 to 6 ... Dermatologic Infections With EGFR/MEK Inhibitors.
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64 Isotretinoin Plus Clindamycin Seem Highly Effective Against ...
https://www.jto.org/article/S1556-0864(15)31816-5/fulltext
Clinical significance and treatment of skin rash from erlotinib in non small cell ... Cetuximab induced acneiform eruption and the response to isotretinoin.
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65 Acute skin toxicity management in head and neck cancer ...
https://www.radioterapiaitalia.it/wp-content/uploads/2015/10/Acute-skin-toxicity-management-in-head-and-neck-cancer-patients-treated-with-radiotherapy-and-chemotherapy-or-EGFR-inhibitors-Literature-review-and-consensus.pdf
Keywords: Skin toxicity; Radiotherapy; Cetuximab; Chemotherapy; Head and neck cancer ... treatment options for skin rash induced by EGFR-targeted therapies:.
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66 Correlation of capecitabine-induced skin toxicity with ... - Nature
https://www.nature.com/articles/bjc2011227
Treatment-related skin toxicity (ST) was evaluated separately for capecitabine and cetuximab. The present analysis investigates the ...
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67 Management of Skin Toxicities of Anti-EGFR Agents in ...
https://www.primescholars.com/articles/management-of-skin-toxicities-of-antiegfr-agents-in-patients-with-pancreatic-cancer-and-other-gi-tumors-by-using-electronic-communication-effective-and-convenient.pdf
In addition, there is slow improvement with medical treatment. Also, ... early, diagnose and treat anti-EGFR related skin rash in order to ...
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68 ERBITUX® (cetuximab) injection, for intravenous use
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/125084s277s280lbl.pdf
Limitations of Use: ERBITUX is not indicated for treatment of Ras- ... ERBITUX can cause dermatologic toxicities, including acneiform rash, skin drying and ...
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69 Chemo Rash & EGFR Rash Treatment - Lindi Skin
https://lindiskin.com/pages/egfr-face-rash
EGFR Rash develops in 50% to 75% of patients and usually occurs within the first few weeks of starting an EGFR antagonist. Skin reactions can be independent of ...
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70 SYMPTOM MANAGEMENT GUIDELINES: ACNEIFORM RASH
http://www.bccancer.bc.ca/nursing-site/Documents/1.%20Acneiform%20Rash.pdf
treatment. Patient Self-assessment: •. Assess skin daily. Notify oncologist at next scheduled visit or earlier if symptoms ...
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71 Managing Side Effects of Vectibix
https://www.vectibix.com/safety-and-side-effects
including skin rash. Depending on the severity of the reaction, your doctor may choose to adjust or delay your dose or stop your treatment.
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72 Risk of High-Grade Skin Rash in Cancer Patients ... - ProQuest
https://search.proquest.com/openview/2ca12a376fdf91fd73002d5aafcbf4e0/1?pq-origsite=gscholar&cbl=41203
Currently, the overall risk of cetuximab-associated skin rash in cancer ... The grading of acne/acneform rash is only described in version III as the ...
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73 Management of Dermatologic Adverse Reactions Associated ...
https://www.unitypoint.org/desmoines/filesimages/cancer%20education/oncology%20nursing%20conference/rash_management_slide_deck_693us13br00398-01-01_3_13.pdf
Severity of rash may be associated with skin phototype1 ... ERBITUX, as a single agent, is indicated for the treatment of patients.
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74 Managing Dermatologic Toxicities Associated With Targeted ...
https://www.oncnursingnews.com/view/managing-dermatologic-toxicities-associated-with-targeted-therapies
Prophylactic treatment of EGFR-associated rash involves the use of skin moisturizer creams and ointments, avoidance of excessive sun ...
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75 Erlotinib-related skin toxicities: Treatment strategies in patients ...
https://www.jaad.org/article/S0190-9622(13)00215-6/fulltext
Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common ...
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76 EGFR Inhibitors: Toxicities and Strategies - Medscape Education
https://www.medscape.org/viewarticle/579711_2
Although the rash of EGFR-inhibitor treatment may resemble acne, clinicians are advised to use descriptive terms such as "pustular/papular rash, pustular ...
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77 Managing EGFR inhibitor side effects in lung cancer patients
https://www.oncologynurseadvisor.com/home/departments/ce-courses/managing-egfr-inhibitor-side-effects-in-lung-cancer-patients/2/
The treatment of EGFR inhibitor-induced rash starts with a method to ... skin rashes and skin conditions that can occur and be graded but ...
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78 IL-36γ drives skin toxicity induced by EGFR/MEK inhibition ...
https://www.jci.org/articles/view/128678
Epidermal growth factor receptor (EGFR) and MEK inhibitors (EGFRi/MEKi) are beneficial for the treatment of solid cancers but are frequently associated with ...
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79 Cetuximab - Side Effects, Uses, Dosage, Overdose ... - RxWiki
https://www.rxwiki.com/cetuximab
Common side effects of cetuximab include acne-like rash, dry or cracking skin, and hair loss. Cetuximab Genetic Information. Colon and rectal ...
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80 Managing EGFR Inhibitor Associated Skin Toxicity - YouTube
https://www.youtube.com/watch?v=hxlkOSizRCQ
Oct 28, 2013
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81 Cetuximab | Marnett Research Laboratory | Vanderbilt University
https://lab.vanderbilt.edu/marnett-lab/cetuximab/
Patients taking cetuximab usually tolerate the drug quite well. The most common side effects are a skin rash and low magnesium levels in the blood. Cetuximab ...
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82 Experts Discuss the Risk of Skin Toxicities Associated With ...
https://www.onclive.com/view/experts-discuss-the-risk-of-skin-toxicities-associated-with-egfr-tkis
Moreover, each individual EGFR TKI can lead to different types of skin rashes and bacteria, making it important to involve dermatologists in ...
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83 Cetuximab rash treatment guidelines - Weebly
https://neritakewu.weebly.com/uploads/1/3/1/8/131856632/8701049.pdf
Cetuximab rash treatment guidelines ... However, skin toxicity - especially acne rash, xerosis and itching - can significantly affect a patient's quality of ...
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84 EGFR inhibitor-induced acneiform eruption - VisualDx
https://www.visualdx.com/visualdx/diagnosis/egfr+inhibitor-induced+acneiform+eruption?diagnosisId=55858&moduleId=101
Onset is within the first 2 weeks of initiation of treatment (range, ... Uncommonly, purpuric skin lesions, including nonfollicular purpuric ...
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85 ERMES study suggests a strategy of de-escalation with only ...
https://ecancer.org/en/video/10655-ermes-study-suggests-a-strategy-of-de-escalation-with-only-cetuximab-in-first-line-therapy-for-ras-and-braf-wild-type-mcrc
› video › 10655-ermes-study-suggests-...
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86 KRAS status and efficacy in the first-line treatment of patients ...
https://slideplayer.com/slide/5680458/
CRYSTAL Trial RANDOMI ZE FOLFIRI + Cetuximab FOLFIRI N=608 N= Endpoint= PFS ... 11 Results Toxicity No difference in skin rash or other toxicity by KRAS ...
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87 8 of the best skin lotions for chemotherapy patients
https://www.medicalnewstoday.com/articles/best-lotion-for-chemo-skin
They may also have a higher chance of developing sunburn, and their cancer treatment may cause a minor rash. Radiation therapy: Dryness and itchiness can ...
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88 Abrams' Angiography: Interventional Radiology - Google Books Result
https://books.google.com/books?id=GU2PAQAAQBAJ&pg=PT293&lpg=PT293&dq=cetuximab+skin+rash+grading&source=bl&ots=pgG80CJbb0&sig=ACfU3U3SLLxXQYBmmKYTNf76yyPlpobDWQ&hl=en&sa=X&ved=2ahUKEwjp8-Geit_7AhV8i3IEHWSmBgkQ6AF6BQjSAhAD
There was a trend toward improved survival with increasing grade of rash ... Grades 3 to 4 diarrhea occurred in 2% of patients receiving cetuximab and in ...
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89 Wound, Ostomy and Continence Nurses Society® Core ...
https://books.google.com/books?id=Wec0CgAAQBAJ&pg=PT1512&lpg=PT1512&dq=cetuximab+skin+rash+grading&source=bl&ots=qKX7eWnvee&sig=ACfU3U110DLW86ZzJuGMRjy8jJzZzxvnrg&hl=en&sa=X&ved=2ahUKEwjp8-Geit_7AhV8i3IEHWSmBgkQ6AF6BQjPAhAD
The incidence of skin rash caused by targeted therapies varies based on the ... the incidence of high-grade rash resulting in treatment interruption was ...
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90 Skeel's Handbook of Cancer Therapy - Google Books Result
https://books.google.com/books?id=NCzfCwAAQBAJ&pg=PT550&lpg=PT550&dq=cetuximab+skin+rash+grading&source=bl&ots=9C1EDGImue&sig=ACfU3U02Zym5UAruiYa5RENs7xHBi9aSdQ&hl=en&sa=X&ved=2ahUKEwjp8-Geit_7AhV8i3IEHWSmBgkQ6AF6BQjRAhAD
The grading scale for PPE is shown in Table 26.10.29 At the first sign of PPE, ... Clinical findings EGFR skin reactions are primarily a pustulopapular rash ...
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