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1 Managing Side Effects of Vemurafenib Therapy for Advanced ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530112/
The rash affected the face, neck, trunk and extremities (Flaherty, 2010), and was variably associated with itching or soreness (Huang, Hepper, ...
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2 Side Effects of Zelboraf (Vemurafenib), Warnings, Uses - RxList
https://www.rxlist.com/zelboraf-side-effects-drug-center.htm
The most common adverse reactions of any grade (≥ 30% in either study) in ZELBORAF-treated patients were arthralgia, rash, alopecia, fatigue, photosensitivity ...
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3 Risk factors for severe rash with use of vemurafenib alone or ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-020-6659-0
Skin toxicities such as skin rash (e.g. erythema, maculopapular rash, folliculitis, keratosis pilaris like eruption), photosensitivity, ...
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4 Zelboraf® (vemurafenib) - Information for Patients - Genentech
https://www.gene.com/patients/medicines/zelboraf
Zelboraf should be used with caution in patients with prior or concurrent cancers associated with RAS mutation. Drug Rash with Eosinophilia and Systemic ...
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5 Common and Rare Side Effects for Zelboraf - WebMD
https://www.webmd.com/drugs/2/drug-156777/zelboraf-oral/details/list-sideeffects
Zelboraf Side Effects by Likelihood and Severity ... a type of bumpy skin rash called a maculopapular rash; a type of slow growing skin cancer called a ...
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6 Understanding Metastatic Melanoma - Cotellic
https://www.cotellic.com/patient/about/metastatic-melanoma.html
Avoid sunlight during treatment with COTELLIC and ZELBORAF. COTELLIC and ZELBORAF can make your skin sensitive to sunlight. You may burn more easily and get ...
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7 Zelboraf Side Effects: Common, Severe, Long Term - Drugs.com
https://www.drugs.com/sfx/zelboraf-side-effects.html
Common side effects of Zelboraf include: squamous cell carcinoma, keratoacanthoma, skin photosensitivity, and erythema of skin.
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8 Vemurafenib (Zelboraf) | Cancer information
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/treatment/cancer-drugs/drugs/vemurafenib
Skin problems can include a rash, dry skin, itching, and reddening of the skin. Your skin might feel thicker or look crusty, scaly or have small raised bumps on ...
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9 Vemurafenib | DermNet
https://dermnetnz.org/topics/vemurafenib
Cutaneous adverse reactions from vemurafenib ; Toxic erythema (morbilliform or scarlatiniform drug rash) ; Scaly skin lesions, ranging from papillomas to ...
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10 Zelboraf (vemurafenib) Drug / Medicine Information
https://www.news-medical.net/drugs/Zelboraf.aspx
If you are taking Zelboraf you may become more sensitive to sunlight and get symptoms of sunburn (such as redness, itching, swelling and blistering) more easily ...
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11 Zelboraf Side Effects - GoodRx
https://www.goodrx.com/zelboraf/side-effects
Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into ...
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12 Zelboraf - Uses, Side Effects, Interactions - MedBroadcast.com
https://www.medbroadcast.com/drug/getdrug/zelboraf
Women: Women may be more at risk for experiencing certain side effects from this medication, including rash, sensitivity to sunlight, and joint pain. Pregnancy: ...
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13 Cutaneous Toxic Effects Associated With Vemurafenib and ...
https://jamanetwork.com/journals/jamadermatology/fullarticle/1149923
Conclusions The development of sorafenib-like cutaneous sequelae (squamous cell carcinomas, keratosis pilaris–like eruptions, seborrheic ...
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14 Vemurafenib (Zelboraf) - UPMC Hillman Cancer Center
https://hillman.upmc.com/-/media/cancercenter/for-patients/documents/chemo-pdfs/vemurafenib.pdf?la=en
You may get a skin rash/reaction while being out in the sun, sun lamps and tanning beds. • Itching. • Skin growths. • Hair loss.
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15 Melanoma Adverse Reaction Profile - Tecentriq
https://www.tecentriq-hcp.com/melanoma/safety-profile/adverse-reactions.html
†Includes rash, rash maculopapular, dermatitis acneiform, rash macular, ... TECENTRIQ, in combination with cobimetinib and vemurafenib, is indicated for the ...
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16 Prospective study of cutaneous side-effects associated with ...
https://www.sciencedirect.com/science/article/pii/S0923753419373016
Both benign and malignant skin tumors occurred during vemurafenib therapy, but the most common cutaneous side-effect consisted in the appearance of benign ...
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17 RASopathic Skin Eruptions during Vemurafenib Therapy - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058721
Follicular rash or scattered pustules appeared in 5/28 (18%) patients, mostly during intermediate treatment phase. In two biopsies, a ...
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18 Vemurafenib After Ipilimumab Linked to Rash - MDedge
https://www.mdedge.com/hematology-oncology/article/55764/melanoma/vemurafenib-after-ipilimumab-linked-rash
Major Finding: Four patients (25%) developed grade 3 maculopapular skin rash that histologically had features of a drug hypersensitivity ...
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19 Zelboraf 240 mg Film-coated Tablets - print friendly - (emc)
https://www.medicines.org.uk/emc/product/3948/xpil/print
Severe skin reactions can happen while taking Zelboraf. Stop taking Zelboraf and talk to your doctor immediately if you get a skin rash with any of the ...
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20 VEMURAFENIB - Capital Health Nova Scotia
http://www.cdha.nshealth.ca/system/files/sites/77/documents/adrmg-vemurafenib.pdf
The most common adverse effects with Vemurafenib are arthralgia, rash, alopecia, fatigue, photosensitivity reaction, nausea, pruritus, and skin papilloma.
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21 vemurafenib – Health Information Library | PeaceHealth
https://www.peacehealth.org/medical-topics/id/d07798a1
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, ...
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22 Skin Reactions to Targeted Therapy and Immunotherapy
https://www.cancer.net/coping-with-cancer/physical-emotional-and-social-effects-cancer/managing-physical-side-effects/skin-reactions-targeted-therapy-and-immunotherapy
This means rashes and changes to the hair and nails may occur during treatment with these drugs. Most people taking drugs that target EGFR ...
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23 Zelboraf, INN-vemurafenib - European Medicines Agency |
https://www.ema.europa.eu/en/documents/product-information/zelboraf-epar-product-information_en.pdf
vemurafenib (see sections 4.3 and 4.8). Severe hypersensitivity reactions may include. Stevens-Johnson syndrome, generalised rash, erythema or hypotension.
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24 For the Patient: Vemurafenib - BC Cancer
http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Vemurafenib_handout.pdf
sunburn or skin reaction such as itching, rash, or swelling contact your doctor. Numbness or tingling of the fingers or toes may rarely occur.
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25 Early Exanthema Upon Vemurafenib Plus Cobimetinib Is ...
https://www.frontiersin.org/articles/10.3389/fonc.2021.672172/full
Thus, in these cancer entities patients presenting with a skin rash under EGFR inhibitor therapy are encouraged to continue this treatment with ...
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26 Is a skin rash associated with the treatment response to vemurafenib ...
https://medivizor.com/blog/SampleLibrary/melanoma/is-a-skin-rash-associated-with-the-treatment-response-to-vemurafenib-and-cobimetinib-in-patients-with-advanced-melanoma/
... of skin rash-like symptoms known as exanthema and its relationship with treatment outcome with vemurafenib (Zelboraf) alone or vemurafenib combined with ...
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27 ZELBORAF - Medsafe
https://www.medsafe.govt.nz/consumers/cmi/z/zelboraf.pdf
Zelboraf 200605. 2. • swelling of the face, lips, tongue or other parts of the body. • rash, itching or hives on the skin.
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28 AIM at Melanoma - TAKING THE MEDICATION
https://www.aimatmelanoma.org/wp-content/uploads/AIM-COLTELLIC-ZELBORAF-MULTIPAGE.pdf
If you miss taking your Zelboraf dose and ... Skin rash. • Nausea ... •A rash. •A new wart. •A skin sore. COTELLIC® (cobimetinib)/ZELBORAF® (vemurafenib).
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29 Vemurafenib (Zelboraf) - Side Effects, Interactions, Uses ...
https://www.everydayhealth.com/drugs/vemurafenib
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, ...
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30 August 2013 (Public Communication) - Roche Canada
https://www.rochecanada.com/content/dam/rochexx/roche-ca/products/ConsumerInformation/MonographsandPublicAdvisories/Zelboraf/ZELBORAF_Aug2013_PC_E.pdf
ZELBORAF® (vemurafenib) and the Risk of Progression of. Certain Types of Cancer and the Risk of Serious Rash.
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31 Zelboraf (Vemurafenib) Oral: Uses, Side Effects, Dosages ...
https://www.verywellhealth.com/zelboraf-vemurafenib-oral-5219641
Zelboraf (vemurafenib) has the potential of causing new skin cancers to develop. These are called cutaneous squamous cell carcinoma, ...
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32 Vemurafenib | Leukemia and Lymphoma Society
https://www.lls.org/drug/vemurafenib
Joint pain, a flat or raised red bump on the skin (rash maculo-papular), hair loss (alopecia), fatigue, electrocardiogram QT interval prolonged, and benign, ...
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33 Incidence, course, and management of toxicities associated ...
https://www.annalsofoncology.org/article/S0923-7534(19)32016-2/pdf
Melanoma, Cancer Immunotherapy and Innovative Therapy, Istituto Nazionale ... with the cobimetinib plus vemurafenib regimen included rash,.
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34 Zelboraf (Vemurafenib) Chemotherapy Drug Information
https://chemocare.com/chemotherapy/drug-info/zelboraf.aspx
Any skin change, irritation, itching or rash. Always inform your health care provider if you experience any unusual symptoms. Precautions: Before starting ...
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35 Zelboraf (vemurafenib) Cancer Medication
https://www.cancerhealth.com/drug/zelboraf
Common side effects include fatigue, nausea, skin rash, itching, photosensitivity, hair loss and joint pain. Potential serious side effects may ...
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36 ZELBORAF® (vemurafeni) Label
https://s3.pgkb.org/attachment/Vemurafenib_09_18_2017_FDA.pdf
of treatment with ZELBORAF. Severe hypersensitivity reactions included generalized rash and erythema,. 67 hypotension, and drug reaction with eosinophilia ...
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37 Zelboraf Oral Tablet 240 mg - Mount Nittany Health
https://mountnittany.org/wellness-article/203_13686_zelboraf-oral-tablet-240-mg
This medicine has been associated with a rare but serious skin rash. If you notice any red, peeling or blistered skin, contact your doctor ...
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38 Advanced Melanoma Treatment | TECENTRIQ® (atezolizumab)
https://www.tecentriq.com/melanoma.html
TECENTRIQ immunotherapy with COTELLIC® (cobimetinib) and ZELBORAF® ... rash; itching; skin blistering or peeling; painful sores or ulcers in mouth or nose, ...
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39 Lupus erythematosus-like skin eruption after vemurafenib ...
https://www.jaad.org/article/S0190-9622(14)01669-7/pdf
Lupus erythematosuselike skin eruption after vemurafenib therapy. To the Editor: Vemurafenib (PLX4032, Zelboraf,. Roche Registration Ltd, Welwyn Garden City ...
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40 Zelboraf and Cotellic | Roche Skin Cancer Treatment
https://cancertreatments.co.nz/skin-cancer/zelboraf/
While you are taking Zelboraf: tell your doctor if you notice any skin changes such as a new wart, a skin sore or reddish bump or a sore that bleeds or does not ...
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41 Vemurafenib oral tablets | Cleveland Clinic
https://my.clevelandclinic.org/health/drugs/18444-vemurafenib-oral-tablets
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you ...
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42 Zelboraf - Side Effects, Uses, Dosage, Overdose ... - RxWiki
https://www.rxwiki.com/zelboraf
Severe skin reactions. Stop taking Zelboraf and call your healthcare provider right away if you get a skin rash with any of the following ...
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43 Zelboraf (vemurafenib) | SkinCancer.net
https://skincancer.net/treatment/targeted-therapy/zelboraf-reviews-how-well-works-side-effects
Taking Vemurafenib can cause other cancers. ... It has been linked to other types of skin cancer called cutaneous squamous cell carcinoma and ...
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44 vemurafenib - Stages Pediatrics, PC
https://stagespediatrics.com/parent-information/child-health-library/health-library?DOCHWID=d07798a1
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( ...
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45 vemurafenib - Kennesaw Gynecology
https://www.kennesawgynecology.com/womens-health/health-library?DOCHWID=d07798a1
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( ...
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46 Vemurafenib - Memorial Sloan Kettering Cancer Center
https://www.mskcc.org/cancer-care/patient-education/medications/vemurafenib
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or ...
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47 vemurafenib - Patient Education - Balloon Sinuplasty
http://oregon-ent.com/patient-education/hw-view.php?DOCHWID=d07798a1
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, ...
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48 Zelboraf - vemurafenib (Rx) - Medscape Reference
https://reference.medscape.com/drug/zelboraf-vemurafenib-999679
However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling ( ...
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49 Targeted Therapy Drugs for Melanoma Skin Cancer
https://www.cancer.org/cancer/melanoma-skin-cancer/treating/targeted-therapy.html
Common side effects can include skin thickening, rash, itching, sensitivity to the sun, headache, fever, joint pain, fatigue, hair loss, and ...
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50 Zelboraf - Product Information
https://www.tga.gov.au/sites/default/files/auspar-vemurafenib-121217-pi.doc
The relative proportions of vemurafenib and its metabolites were characterized ... of any skin changes, including rash and photosensitivity.
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51 Vemurafenib - Hematology Oncology Associates of ...
https://www.hoafredericksburg.com/vemurafenib/
Joint pain; Rash; Hair loss; Fatigue; Sunburn or sun sensitivity ... Zelboraf may cause a type of skin cancer known as cutaneous squamous cell carcinoma.
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52 vemurafenib - NorthShore University HealthSystem
https://www.northshore.org/healthresources/encyclopedia/encyclopedia.aspx?DocumentHwid=d07798a1
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( ...
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53 Ultraviolet A and Photosensitivity during Vemurafenib Therapy
https://www.nejm.org/doi/full/10.1056/nejmc1113752
Common toxic effects observed with vemurafenib include arthralgia, rash, fatigue, and photosensitivity. ... In our experience, some patients have ...
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54 ZELBORAF® (Vemurafenib) - Oncopod- Chemotherapy Drugs ...
https://www.mozocare.com/oncopod/chemotherapy/vemurafenib/
Risk of cancers. ZELBORAF may cause a type of skin cancer called cutaneous squamous cell carcinoma (cuSCC). New melanoma lesions have occurred in people who ...
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55 VEMURAFENIB | Oncohealth Institute
http://www.oncohealth.eu/en/patient-area/understanding-cancer/patient-information-support/general-information/treatment/biological-therapy/list-drugs/vemurafenib
Some mild changes to the skin are common with vemurafenib. These include rash, itchiness, dry or scaly skin, or warts. You should let your nurse or doctor ...
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56 Help Manage Toxicities With BRAF and MEK Inhibitors
https://www.pharmacytimes.com/view/help-manage-toxicities-with-braf-and-mek-inhibitors
Watch for alopecia, arthralgia, diarrhea, fatigue, nausea, pyrexia, rash, and vomiting, among others.
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57 vemurafenib - Thomas J. Vasdekas, MD, FACS | Orland Park
https://advancedsurgicalconsultantsllc.com/health-library/hw-view.php?DOCHWID=d07798a1
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( ...
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58 vemurafenib - Health Library - Colon Rectal Associates
http://www.colonrectalhealth.com/health-library/hw-view.php?DOCHWID=d07798a1
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, ...
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59 Zelboraf® - Healthdirect
https://media.healthdirect.org.au/medicines/GuildLink_Information/183674/CMI/roczelbo10320.pdf
contains the active ingredient vemurafenib. Consumer Medicine Information ... melanoma (a type of skin cancer that ... rash, itching or hives on the skin.
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60 The Cutaneous Side Effects of Selective BRAF Inhibitors and ...
https://link.springer.com/article/10.1007/s13671-013-0039-9
In clinical trials and subsequent dermatology-reported cohorts, “rash” was reported to occur in 18–70 % of patients treated with vemurafenib ...
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61 vemurafenib patient.pdf - Cancer Care Ontario
https://www.cancercareontario.ca/en/system/files_force/vemurafenib%20patient.pdf?download=1
Other Name: Zelboraf®. Appearance: tablet. What is this medication for? For treating a type of skin cancer called melanoma that has spread to other parts of ...
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62 What is Zelboraf: Uses, Warnings & Interactions - SingleCare
https://www.singlecare.com/prescription/zelboraf/what-is
Zelboraf is used to treat patients with melanoma. The generic name of Zelboraf is Vemurafenib. The average Zelboraf price is about $5,295 for a supply of ...
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63 ZELBORAF® (vemurafeni) Label
http://www.crlonline.com/lco/medguides/625364.pdf
ZELBORAF may cause a type of skin cancer called cutaneous squamous cell ... and call your healthcare provider right away if you get a skin rash with.
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64 FLASCO / FDA Approves Genentech's Cotellic™ (Cobimetinib ...
https://www.flasco.org/fda-approves-genentechs-cotellic-cobimetinib-in-combination-with-zelboraf-vemurafenib-in-advanced-melanoma/
All study participants received vemurafenib and were then randomly ... hemorrhage and severe skin rash due to increased sensitivity to ...
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65 Severe Adverse Reaction to Vemurafenib in a Pregnant ...
https://www.karger.com/article/fulltext/487128
Various adverse reactions to vemurafenib are common but range from mild skin rash (in over 90% of patients) to severe dermatotoxic, ...
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66 ZELBORAF® (vemurafenib) tablet
http://shijiebiaopin.net/upload/product/20144722183114.pdf
ZELBORAF may cause a type of skin cancer called cutaneous squamous cell ... away if you get a skin rash with any of the following symptoms, because you may ...
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67 Drug Notes - Vemurafenib (By mouth) - A.D.A.M.
http://slu.adam.com/content.aspx?productid=45&pid=45&gid=5862
Treats melanoma (skin cancer) and Erdheim-Chester Disease (ECD). ... Blistering, peeling, red skin rash; Dark urine or pale stools, nausea, vomiting, ...
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68 Insight - How new cancer drugs can skip randomized trials
https://www.reuters.com/article/uk-cancer-drugs-insight/insight-how-new-cancer-drugs-can-skip-randomized-trials-idUKBRE98P05K20130926
The Zelboraf trial fuelled support for a new “breakthrough therapy” ... fevers, skin rash, loss of skin colour and muscle weakness.
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69 Zelboraf (Vemurafenib) - Canada Pharmacy Online
https://www.canadapharmacyonline.com/DrugInfo.aspx?name=Zelboraf6859
Blurred vision, increased sensitivity to light; ... Hair loss; ... Joint pain; ... Mild skin rash or itching; ... Nausea, vomiting; ... Skin growths; ... Tired feeling.
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70 Vemurafenib (By mouth) | Drug Notes | Health Information
https://www.stlukes-stl.com/health-content/drug-notes/45/5862.htm
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing ...
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71 Vemurafenib (Zelboraf®) - Children's Minnesota
https://www.childrensmn.org/educationmaterials/childrensmn/article/17938/vemurafenib-zelborafr/
Always cover your child's skin with long sleeves and pants, wear a hat, and wear sunscreen and lip balm SPF 30 or higher; Headache; Dizziness; Itchy rash ...
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72 ZELBORAF USPI 07032013 MASTER.pdf - PDR.Net
https://www.pdr.net/labels/Communications/1000182/Zelboraf%20USPI%2007032013%20MASTER.pdf
Severe hypersensitivity reactions included generalized rash and erythema or hypotension. Permanently discontinue ZELBORAF in patients who experience a ...
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73 Zelboraf (vemurafenib) cancer medicine information | myVMC
https://www.myvmc.com/drugs/zelboraf/
Severe skin rash, itching, hives;; Severe blisters or bleeding of your lips, mouth, nose, or eyes;; A severe skin reaction starting with painful ...
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74 BRAF, MEK and KIT inhibitors for melanoma: adverse events ...
https://cco.amegroups.com/article/view/3807/html
To this stage, two selective BRAF inhibitors, vemurafenib and dabrafenib, ... (72) found an association between CK elevation and skin rash of novel targeted ...
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75 Vemurafenib (Zelboraf®) - Dana-Farber Cancer Institute
https://www.dana-farber.org/uploadedFiles/Pages/Health_Library/Articles/Vemurafenib-Zelboraf.pdf
Please talk to your doctor or nurse about what you can take for this. 7. Skin changes, such as dryness, rash, or darkening of skin, may occur on your body.
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76 ZELBORAF Clinical Pharmacology Drug Monograph
https://www.wellrx.com/ZELBORAF/monographs/
Permanently discontinue vemurafenib in patients who experience a severe skin reaction. Rash (unspecified) (37%; grade 3, 8%), maculopapular rash (9%; grade ...
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77 Vemurafenib (Zelboraf) National Drug Monograph November ...
https://www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/VemurafenibDrugMonograph.pdf
vemurafenib patients and 1% of dacarbazine patients. Common Adverse Events. Arthralgia, rash, alopecia, fatigue, photosensitivity reaction, nausea, ...
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78 18 MEDICATION GUIDE ZELBORAF® (ZEL-bor-raf ...
http://online.lexi.com/lco/medguides/648521.pdf
Severe skin reactions. Stop taking ZELBORAF and call your healthcare provider right away if you get a skin rash with any of the following symptoms because ...
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79 Zelboraf - Pharmasave
https://pharmasave.com/health/medications/zelboraf/
allergic reactions including rash, feeling faint, trouble breathing, or swelling of the face, lips, or tongue; signs of pancreatitis (e.g., abdominal pain on ...
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80 Tecentriq Plus Cotellic and Zelboraf Approved for Advanced ...
https://www.empr.com/home/news/tecentriq-cobimetinib-vemurafenib-braf-v600-melanoma-patients/
Regarding safety, the most common adverse reactions (≥20%) in patients treated with atezolizumab plus cobimetinib and vemurafenib were rash ...
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81 Vemurafenib: MedlinePlus Drug Information
https://medlineplus.gov/druginfo/meds/a612009.html
Why is this medication prescribed? ... Vemurafenib is used to treat certain types of melanoma (a type of skin cancer) that cannot be treated with ...
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82 Vemurafenib-associated bullous DRESS syndrome
https://ascopubs.org/doi/10.1200/jco.2013.31.15_suppl.e20041
Treatment was discontinued 1 month later because of a grade 2 rash and nausea. Treatment was re-introduced 10 days later with reduction of the ...
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83 FDA Grants New Indication for Tecentriq Plus Cotellic and ...
https://www.pharmacypracticenews.com/FDA-Approvals/Article/09-20/FDA-Grants-New-Indication-for-Tecentriq-Plus-Cotellic-and-Zelboraf-for-Advanced-Melanoma/59217?MvBriefArticleId=27468
The most common adverse reactions in patients who received atezolizumab plus cobimetinib and vemurafenib were rash, musculoskeletal pain, fatigue, ...
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84 vemurafenib | Cigna
https://www.cigna.com/knowledge-center/hw/medications/vemurafenib-d07798a1.html
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction ( ...
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85 Vemurafenib + Cobimetinib for Melanoma - ChemoExperts
https://www.chemoexperts.com/vemurafenib-zelboraf-cobimetinib-cotellic-melanoma.html
Vemurafenib (Zelboraf®) · Rash and sun-sensitivity are common. Patients taking vemurafenib should avoid direct and prolonged sun exposure and use ...
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86 Genentech Announces Phase III Study Results for Tecentriq ...
https://www.biospace.com/article/releases/genentech-announces-phase-iii-study-results-for-tecentriq-plus-cotellic-and-zelboraf-in-people-with-previously-untreated-braf-v600-mutation-positive-advanced-melanoma/
Severe skin reactions. Patients should stop taking Zelboraf and call their healthcare provider right away if they get a skin rash with any of ...
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87 Cobimetinib Approved for Advanced Melanoma - NCI
https://www.cancer.gov/news-events/cancer-currents-blog/2015/cobimetinib-melanoma
Patients who received vemurafenib plus cobimetinib had a median progression-free ... retinal detachment, severe skin rash, and liver damage.
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88 Zelboraf - Rexall
https://www.rexall.ca/article/drug/view/id/6196/
What side effects are possible with this medication? · allergic reactions including rash, feeling faint, trouble breathing, or swelling of the face, lips, or ...
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89 Cutaneous adverse events of molecularly targeted therapy ...
https://www.uptodate.com/contents/cutaneous-adverse-events-of-molecularly-targeted-therapy-and-other-biologic-agents-used-for-cancer-therapy
Severe Imatinib-Associated Skin Rash in Gastrointestinal Stromal Tumor Patients: Management and Clinical Implications. Cancer Res Treat 2016; 48 ...
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90 Skin toxicity of targeted therapy: vemurafenib, first experiences ...
https://typeset.io/pdf/skin-toxicity-of-targeted-therapy-vemurafenib-first-w7ttuepclu.pdf
Two out of five (40%) vemurafenib treated pati- ents experienced photosensitivity, three (60%) had rash eruptions, four (80%) developed alopecia, and.
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91 Management of BRAF and MEK inhibitor toxicities in patients ...
https://journals.sagepub.com/doi/pdf/10.1177/1758834014566428
pattern of onset of vemurafenib side effects is also predictable: photosensitivity and rash occur usu- ally within days of starting the drug. Arthralgia,.
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92 Zelboraf - Main Header
https://www.nps.org.au/assets/medicines/a422791b-524c-4656-ae00-a53300ff6e8a.pdf
contains the active ingredient vemurafenib ... Zelboraf. When you must not take it. Do not take Zelboraf if: ... rash, itching or hives on the skin.
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93 FDA Approves Cotellic Combo Therapy for Advanced Melanoma
https://journals.lww.com/oncology-times/fulltext/2015/12100/fda_approves_cotellic_combo_therapy_for_advanced.29.aspx
The safety and efficacy of Cotellic used in combination with vemurafenib ... severe skin rash, hepatoxicity, hemorrhage, and severe skin reaction due to ...
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94 vemurafenib - St. Luke's
https://www.stlukesonline.org/health-services/health-information/healthwise/2017/06/27/13/13/vemurafenib
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, ...
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