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1 Shire's Takhzyro expected to dominate in hereditary ...
https://clarivate.com/blog/shires-takhzyro-anticipated-to-dominate-the-market-following-on-track-approval-in-hereditary-angioedema/
Shire's Cinryze (C1 esterase inhibitor [human]) is the dominant brand for prevention of angioedema attacks, but one of its main drawbacks is its ...
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2 FDA Approves Shire's Takhzyro for Hereditary Angioedema
https://www.biospace.com/article/fda-approves-shire-s-takhzyro-for-hereditary-angioedema/
The U.S. Food and Drug Administration (FDA) approved Shire's Takhzyro (lanadelumab-flyo) injection to prevent attacks of hereditary angioedema ( ...
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3 Shire eyes blockbuster sales with 'best-in-class' HAE drug ...
https://www.fiercepharma.com/pharma/shire-eyes-blockbuster-sales-best-class-hae-drug-takhzyro
Shire's got a brand-new approval on its hands that could help it dominate the hereditary angioedema (HAE) market for years to come—and rack up blockbuster sales ...
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4 Shire Receives European Approval for TAKHZYRO ... - Takeda
https://www.takeda.com/newsroom/shire-news-releases/2018/khjtww/
Shire Receives European Approval for TAKHZYRO™ (lanadelumab) subcutaneous injection, for the Preventive Treatment of Hereditary Angioedema.
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5 Current state of hereditary angioedema management - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405601/
Hereditary angioedema (HAE) is a chronic disease with a high burden of disease that is poorly understood and often misdiagnosed. Availability of treatments ...
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6 FDA Approves Shire's Preventive Treatment Takhzyro for ...
https://angioedemanews.com/news/fda-approves-takhzyro-shire-hereditary-angioedema-preventive-treatment/
SHP616 is a therapy that Shire developed to prevent the acute swelling attacks of hereditary angioedema. The treatment candidate is administered as an ...
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7 Shire set to file for lanadelumab in hereditary angioedema
https://www.fiercebiotech.com/biotech/hae-everyone-shire-just-set-up-a-filing-for-lanadelumab
Shire's new drug lanadelumab has been tipped to make $2 billion at peak. Shire's dominant position in the hereditary angioedema (HAE) market just firmed up with ...
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8 HAE Treatment: TAKHZYRO® (lanadelumab-flyo), Official Site
https://www.takhzyro.com/
TAKHZYRO is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in people 12 years of age and older. It is not known if TAKHZYRO is ...
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9 Shire gets US approval for hereditary angioedema drug
https://www.labiotech.eu/more-news/shire-approval-hereditary-angioedema-drug/
The UK-US biotech giant's drug Takhzyro has been approved by the FDA to prevent attacks of hereditary angioedema, a rare genetic disease ...
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10 Shire Announces FDA Approval of TAKHZYRO™
https://www.globenewswire.com/en/news-release/2018/08/27/1557233/0/en/Shire-Announces-FDA-Approval-of-TAKHZYRO-lanadelumab-flyo-a-First-of-its-Kind-mAb-Preventive-Treatment-for-Hereditary-Angioedema.html
In the Phase III HELP (Hereditary Angioedema Long-term Prophylaxis) Study™ supporting FDA approval, TAKHZYRO reduced the number of monthly HAE ...
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11 Shire's Takhzyro wins US approval in hereditary angioedema
https://www.thepharmaletter.com/article/shire-s-takhzyro-wins-us-approval-in-hereditary-angioedema
Irish pharma major Shire (LSE: SHP) announced on Friday that the US Food and Drug Administration (FDA) had granted approval for Takhzyro ...
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12 Effectiveness of lanadelumab for preventing hereditary ...
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cea.13974
Hereditary angioedema (HAE) with C1-inhibitor (C1-INH) deficiency, a rare autosomal dominant disease caused by SERPING1 gene mutations, is ...
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13 US Hereditary Angioedema Association
https://www.haea.org/page/show/press/8/shire_phase3
Learn more at shire.com. ... FIRAZYR is a medicine used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older.
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14 Hereditary Angioedema - ICER
https://icer.org/assessment/hereditary-angioedema-2018/
C1 esterase inhibitors (Haegarda®, CSL Behring; Cinryze®, Shire). In 2018, ICER assessed the comparative clinical effectiveness and value of therapies for ...
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15 Efficacy and Safety Study of DX-2930 to Prevent Acute ...
https://clinicaltrials.gov/ct2/show/NCT02586805
View this study on Beta.ClinicalTrials.gov. Sponsor: Shire. Collaborator: ... Rate of Investigator Confirmed Hereditary Angioedema (HAE) Attacks During ...
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16 FIRAZYR® (icatibant injection)
https://www.firazyr.com/
FIRAZYR is indicated for the treatment of acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. Learn More About FIRAZYR ...
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17 Shire's Investigational Treatment Lanadelumab Reduces ...
https://www.prnewswire.com/news-releases/shires-investigational-treatment-lanadelumab-reduces-hereditary-angioedema-monthly-attack-rate-by-87-versus-placebo-in-phase-3-26-week-pivotal-trial-622936414.html
Shire's Investigational Treatment Lanadelumab Reduces Hereditary Angioedema Monthly Attack Rate by 87% Versus Placebo in Phase 3 26-week ...
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18 Assessment and management of disease burden and quality ...
https://aacijournal.biomedcentral.com/articles/10.1186/s13223-021-00537-2
Hereditary angioedema (HAE) is a rare disease characterized by unpredictable, potentially life-threatening attacks, resulting in significant ...
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19 Individual approach to long-term therapy in patients ... - Frontiers
https://www.frontiersin.org/articles/10.3389/falgy.2022.949387/full
Hereditary angioedema (HAE) is caused by C1-Inhibitor (C1-INH) deficiency leading to recurrent attacks of skin swellings, abdominal pain, and ...
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20 Contributor disclosures - UpToDate
https://www.uptodate.com/contents/hereditary-angioedema-due-to-c1-inhibitor-deficiency-general-care-and-long-term-prophylaxis/contributor-disclosure
Disclosure: Grant/Research/Clinical Trial Support: CSL Behring [Hereditary angioedema]; Pharming [Hereditary angioedema]; Shire/Takeda [Hereditary angioedema].
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21 The Threats And Opportunities In Hereditary Angioedema
https://seekingalpha.com/article/4034531-threats-and-opportunities-in-hereditary-angioedema-what-next-for-shire
Shire currently dominates the HAE market with the leading treatment for both the long-term prophylaxis (Cinryze), and the Acute Setting (Firazyr) ...
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22 Advances in Hereditary Angioedema: The Prevention of ...
https://journals.lww.com/journalofinfusionnursing/Fulltext/2020/05000/Advances_in_Hereditary_Angioedema__The_Prevention.4.aspx
Hereditary angioedema (HAE) due to C1 esterase inhibitor (C1-INH) deficiency (C1-INH-HAE) is a rare genetic, autosomal dominant disease with an estimated ...
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23 First preventive mAb for hereditary angioedema - Nature
https://www.nature.com/articles/nbt1118-1027
The US Food and Drug Administration has approved the first monoclonal antibody (mAb) to prevent hereditary angioedema (HEA) attacks.
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24 Hereditary Angioedema - Medscape Education
https://www.medscape.org/sites/advances/angioedema-hereditary
Hereditary angioedema (HAE) impacts patients' quality of life (QoL), but physicians are often challenged with providing optimal care for them.
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25 Takhzyro for Hereditary Angioedema - Pharmacy Times
https://www.pharmacytimes.com/view/takhzyro-for-hereditary-angioedema
On August 23, 2018, the FDA approved lanadelumab-flyo (Takhzyro; Shire) for the prophylaxis treatment and prevention of hereditary ...
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26 Current and Emerging Therapies to Prevent Hereditary ...
https://ajmc.s3.amazonaws.com/_media/_pdf/AJMC_ACE0096_08_2018_HAE_Article02.pdf
Hereditary angioedema (HAE) is a rare genetic disease defined by recurrent ... Hereditary Angioedema Association, BioCryst, CSL Behring, Circassia, Shire;.
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27 Hereditary Angioedema Agents | AmeriHealth
https://www.amerihealth.com/pdfs/providers/pharmacy_information/pharmacy_policies/hereditary-angioedema-agents.pdf
Accessed. August 10, 2022. Cinryze® (C1 esterase inhibitor [human]). [package insert]. Lexington, MA: Shire ViroPharma Inc. January 2021.
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28 Long-term prevention of hereditary angioedema attacks with ...
https://pennstate.pure.elsevier.com/en/publications/long-term-prevention-of-hereditary-angioedema-attacks-with-lanade
by HELP OLE Investigators · 2022 · Cited by 14 —
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29 Hereditary angioedema - Wikipedia
https://en.wikipedia.org/wiki/Hereditary_angioedema
Hereditary angioedema (HAE) is a disorder that results in recurrent attacks of severe swelling. ... The swelling most commonly affects the arms, legs, face, ...
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30 CINRYZE® (C1 esterase inhibitor [human]) for Hereditary ...
https://www.cinryze.com/
With hereditary angioedema (HAE), it takes courage to embrace a preventive approach. CINRYZE® (C1 esterase inhibitor [human]) was the first FDA-approved ...
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31 Hereditary Angioedema - Texas Health and Human Services
https://www.hhs.texas.gov/sites/default/files/documents/apr-2022-durb-agenda-item5v.pdf
generic, Shire ... Hereditary angioedema (HAE) is a rare, dominant autosomal genetic disorder that affects approximately.
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32 How do patients and physicians communicate about ... - PLOS
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0260805
Hereditary angioedema (HAE) is a rare disease that manifests as recurrent and debilitating angioedema attacks, significantly impacting ...
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33 Shire Gains EU Approval for its Preventive Treatment of ...
https://www.pharmtech.com/view/shire-gains-eu-approval-its-preventive-treatment-hereditary-angioedema
Shire Gains EU Approval for its Preventive Treatment of Hereditary Angioedema ... Shire has announced that the European Commission has granted ...
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34 FDA OKs New Prophylactic Drug for Rare Hereditary ...
https://www.medscape.com/viewarticle/901177
The US Food and Drug Administration (FDA) has approved lanadelumab (Takhzyro, Shire), the first monoclonal antibody to help prevent attacks ...
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35 Hereditary Angioedema Management: From Dealing to ...
https://www.emjreviews.com/allergy-immunology/symposium/hereditary-angioedema-management-from-dealing-to-leading-j01121/
Hereditary angioedema (HAE) is a rare genetic disease that manifests as recurrent cutaneous or submucosal oedema, most commonly affecting the ...
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36 New medicine for hereditary angioedema, a rare disease ...
https://www.ema.europa.eu/en/news/new-medicine-hereditary-angioedema-rare-disease-causing-swelling-beneath-skin
› news › new-medicine-her...
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37 Shire's lanadelumab shown to significantly cut HAE attacks
https://www.pharmatimes.com/news/shires_lanadelumab_shown_to_significantly_cut_hae_attacks_1260707
... lanadelumab provides a significant and clinically meaningful reduction of hereditary angioedema (HAE) attacks. - News - PharmaTimes.
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38 Hereditary angioedema: an update on causes, manifestations ...
https://www.magonlinelibrary.com/doi/10.12968/hmed.2019.80.7.391
Hereditary angioedema is a rare genetic disorder caused by deficiency of C1 esterase inhibitor (C1-INH) and characterized by recurrent ...
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39 Efficacy of Lanadelumab in Hereditary Angioedema Patients ...
https://www.jacionline.org/article/S0091-6749(19)32322-X/fulltext
Lanadelumab prevented hereditary angioedema (HAE) attacks in the phase 3 HELP Study. Previous use of long-term prophylaxis (LTP) may indicate greater HAE ...
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40 Shire gets EC approval for hereditary angioedema jab
https://www.sharecast.com/news/news-and-announcements/shire-gets-ec-approval-for-hereditary-angioedema-jab--3621872.html
Shire's injectable treatment for hereditary angioedema (HAE) has been cleared for launch in Europe, having enjoyed early success in the US.
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41 Current and Prospective Targets of Pharmacologic Treatment ...
https://link.springer.com/article/10.1007/s12016-021-08832-x
Hereditary angioedema (HAE) is a rare disease that causes episodic attacks of subcutaneous and submucosal edema, which can be painful, ...
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42 hereditary angioedema - Discover HAE
https://www.discoverhae.com/hcp
HAE is a rare disease that affects about 1 in 50,000 people in the entire world. It is characterized by recurrent attacks of angioedema without urticaria or ...
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43 Consensus on treatment goals in hereditary angioedema
https://www.sciencedirect.com/science/article/pii/S0091674921008216
Hereditary angioedema (HAE) is a genetic disease primarily caused by SERPING1 mutations, leading to deficiency or dysfunction of C1-inhibitor (HAE-1/2)., HAE ...
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44 Hereditary Angioedema (HAE), Treatment and Prophylaxis
https://www.uhcprovider.com/content/dam/provider/docs/public/policies/exchange/hereditary-angioedema-treatment-prophylaxis-iex.pdf
o Diagnosis of hereditary angioedema (HAE) as confirmed by one of the following: ... Lexington, MA: Shire ViroPharma, Inc., January 2021.
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45 Lanadelumab for preventing recurrent attacks of hereditary ...
https://njl-admin.nihr.ac.uk/document/download/2029640
Andrew walker declares consultancy work for Takeda and SHIRE who make ... Hereditary angioedema (HAE) is a rare genetic disorder affecting ...
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46 Overview of Epidemiology, Pathophysiology, and Disease ...
https://www.ajmc.com/view/ace010_13jun_lumry1_s103to10
Hereditary angioedema (HAE) is an autosomal dominant disease caused by a deficiency in functional C1 inhibitor affecting an estimated 1 in ...
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47 Managing the Female Patient with Hereditary Angioedema
https://journals.sagepub.com/doi/pdf/10.2217/whe.16.6
Hereditary angioedema (HAE) is a rare disorder resulting from decreased functional ... (Firazyr®/Shire) and recombinant C1-INH (rhC1-.
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48 The new england - journal of medicine
https://www.nejm.org/doi/pdf/10.1056/NEJMoa0805538
Hereditary angioedema due to C1 inhibitor deficiency is characterized by ... Pharmaceuticals, ViroPharma, Shire, Dyax, and CSL Behring;.
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49 FDA Approves Shire's Projected Blockbuster HAE Treatment ...
https://www.genengnews.com/news/fda-approves-shires-projected-blockbuster-hae-treatment-takhzyro/
Last year Shire trumpeted results from the Phase III HELP (Hereditary Angioedema Long-term Prophylaxis) Study™ (NCT02586805), which showed ...
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50 Hereditary Angioedema - EOCCO.com
https://www.eocco.com/-/media/EOCCO/PDFs/Formulary/hereditary_angioedema.pdf
Shire Orphan Therapies, LLC. November 2015. 5. Cinryze [Prescribing Information]. Lexington, MA. ViroPharma Biologics, Inc. June 2018. 6. Ruconest ...
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51 FDA Approves Lanadelumab for Hereditary Angioedema
https://www.hcplive.com/view/fda-approves-lanadelumab-for-hereditary-angioedema
... Shire Pharmaceutical's lanadelumab (Takhzyro, SHP643), for the treatment of types I and II hereditary angioedema (HAE) in patients aged ...
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52 Angioedema Treatment Market [2022] In-Depth Analysis And ...
https://www.medgadget.com/2022/01/angioedema-treatment-market-2022-in-depth-analysis-and-business-development-strategies-includes-top-players-like-shire-plc-csl-limited-pharming-group-nv.html
For instance in 2014, Shire Canada Inc. received approval for its FIRAZYR (icatibant injection) in Canada. FIRAZYR is indicated for the ...
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53 US HAEA Medical Advisory Board 2020 Guidelines for the ...
https://www.jaci-inpractice.org/article/S2213-2198(20)30878-3/fulltext
Hereditary angioedema (HAE) is a rare autosomal dominant disease characterized by episodic unpredictable swelling. The United States Hereditary ...
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54 Hereditary Angioedema
https://ldh.la.gov/assets/HealthyLa/PDL/6.24.21/Hereditary.Angioedema.06012021.pdf
request clinical authorization for medications used to treat or prevent hereditary angioedema ... Lexington, MA: Shire Orphan Therapies LLC; August 2020.
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55 Shire's angioedema drug succeeds in late-stage study - Reuters
https://www.reuters.com/article/shire-study/shires-angioedema-drug-succeeds-in-late-stage-study-idUSL4N1IK40T
May 18 (Reuters) - Shire Plc said on Thursday its drug for hereditary angioedema (HAE), a disorder characterized by recurrent episodes of severe ...
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56 hereditary angioedema | The Medical Letter Inc.
https://secure.medicalletter.org/taxonomy/term/15348
The FDA has approved icatibant (Firazyr – Shire), a selective bradykinin B2 receptor antagonist, for treatment of acute attacks of hereditary angioedema ...
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57 Final Results from the Longest Hereditary Angioedema Study ...
https://www.businesswire.com/news/home/20210805005209/en/Final-Results-from-the-Longest-Hereditary-Angioedema-Study-of-Active-Treatment-Duration-Conducted-to-Date-Support-the-Sustained-Safety-and-Efficacy-of-TAKHZYRO%C2%AE-lanadelumab-Injection-for-Long-Term-Prevention-of-Hereditary-Angioedema-Attacks
Hereditary angioedema (HAE) is a rare genetic disorder that results in recurring attacks of oedema – swelling – in various parts of the body, ...
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58 findings from the Icatibant Outcome Survey | Clinical and ...
https://academic.oup.com/cei/article/188/1/148/6411959
Icatibant is used to treat acute hereditary angioedema with C1 inhibitor deficiency types I/II (C1-INH-HAE types I/II) and has shown promise in angioedema ...
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59 Hereditary angioedema - Accredo
https://www.accredo.com/conditions/hereditary-angioedema
Hereditary angioedema, or HAE, is a rare, potentially disabling and life-threatening genetic disorder characterized by episodes of severe swelling ...
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60 Approval in hand, Shire's next step is to deliver on high hopes ...
https://www.biopharmadive.com/news/approval-in-hand-shires-next-step-is-to-deliver-on-high-hopes-for-lanadel/530887/
Shire's much-anticipated prophylaxis treatment for a rare disease that ... causes of the disease, known as hereditary angioedema or HAE.
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61 Lanadelumab for the treatment of hereditary angioedema
https://www.tandfonline.com/doi/abs/10.1080/14712598.2019.1685490
Introduction: Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare yet still probably underdiagnosed clinical condition.
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62 New Drug Approved To Treat Hereditary Angioedema Attacks
https://www.ashp.org/news/2011/08/25/new_drug_approved_to_treat_hereditary_angioedema_attacks
Shire said icatibant treats acute attacks of hereditary angioedema by blocking the bradykinin B2 receptor. This blockade stops the buildup ...
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63 Self-Management Plans in Patients with Hereditary Angioedema
https://www.dovepress.com/self-management-plans-in-patients-with-hereditary-angioedema-strategie-peer-reviewed-fulltext-article-JAA
Hereditary angioedema (HAE) is a rare genetic disorder inherited in an autosomal dominant fashion. It is characterised by the occurrence of ...
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64 Review of Recent Guidelines and Consensus Statements on ...
https://www.karger.com/Article/Fulltext/351232
Consensus meetings and the resulting recommendations shape treatment choices in rare diseases such as hereditary angioedema (HAE) because ...
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65 Hereditary Angioedema Agents - Molina Healthcare
https://www.molinahealthcare.com/-/media/Molina/PublicWebsite/PDF/Providers/common/pa-criteria/Hereditary-Angioedema-Agents-C21463-A.pdf
A. TREATMENT OF ACUTE HEREDITARY ANGIOEDEMA ATTACKS (Firazyr, Berinert, Ruconest, ... Lexington, MA: Shire Orphan Therapies Inc;April 2020.Craig T,.
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66 RX.PA.007.MPC Prophylactic Hereditary Angioedema Products
https://www.marylandphysicianscare.com/wp-content/uploads/2022/03/RX.PA_.007.MPC-Prophylactic-Hereditary-Angioedema-Products-Cinryze-Haegarda-and-Takhzyro.pdf
Hereditary Angioedema (HAE) – a rare disorder characterized by recurrent attacks of ... Lexington, MA: Shire Pharmaceuticals Corp; 2018.
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67 Shire Receives European Approval for TAKHZYRO ...
https://www.pharmaadvancement.com/drug-development/fda-approvals/shire-receives-european-approval-for-takhzyro-lanadelumab-subcutaneous-injection-for-the-preventive-treatment-of-hereditary-angioedema/
The Phase III HELP (Hereditary Angioedema Long-term Prophylaxis) Study™ supporting the approval was recently published in JAMA. The primary ...
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68 Shire plans filing for HAE drug after phase 3 success -
https://pharmaphorum.com/news/shire-plans-filing-hae-drug-phase-3-success/
Shire plans to file its lanadelumab for the rare genetic disorder, hereditary angioedema (HAE), on the back of new phase 3 data showing the ...
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69 Shire's Takhzyro get US FDA approval for preventive ...
http://www.pharmabiz.com/NewsDetails.aspx?aid=110854&sid=2
In the phase III HELP (Hereditary Angioedema Long-term Prophylaxis) Study supporting FDA approval, Takhzyro reduced the number of monthly HAE ...
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70 Shire Receives European Approval for Label Extension of ...
https://www.americanpharmaceuticalreview.com/1315-News/335180-Shire-Receives-European-Approval-for-Label-Extension-of-CINRYZE-to-Prevent-and-Treat-Hereditary-Angioedema-HAE-Attacks-in-Pediatric-Patients-with-HAE/
Shire Receives European Approval for Label Extension of CINRYZE to Prevent and Treat Hereditary Angioedema (HAE) Attacks in Pediatric ...
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71 Shire mAb receives US FDA approval, holding blockbuster ...
https://www.biopharma-reporter.com/Article/2018/08/24/Shire-mAb-receives-US-FDA-approval-holding-blockbuster-expectations
Shire's Takhzyro has been granted approval by the FDA for the treatment of hereditary angioedema.
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72 Shire's angioedema drug Takhzyro claims EU approval
https://www.pmlive.com/pharma_news/shires_angioedema_drug_takhzyro_claims_eu_approval_1268527
Shire has been granted approval by the EMA for rare disease drug Takhzyro, a blockbuster-in-waiting for the rare disease hereditary ...
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73 Shire's Takhzyro gets FDA nod for the treatment of Hereditary ...
https://www.biospectrumindia.com/news/57/11578/shires-takhzyro-gets-fda-nod-for-the-treatment-of-hereditary-angioedema.html
Shire plc, the leading global biotechnology company focused on rare diseases has ... In the Phase III HELP (Hereditary Angioedema Long-term ...
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74 Shire reports positive data from Phase III lanadelumab trial
https://www.clinicaltrialsarena.com/news/shire-reports-positive-data-lanadelumab/
Shire has reported positive results from the Phase III hereditary angioedema long-term prophylaxis (HELP) trial assessing the efficacy and ...
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75 First-of-its-Kind Therapy Approved to Prevent Hereditary ...
https://www.empr.com/home/news/first-of-its-kind-therapy-approved-to-prevent-hereditary-angioedema-attacks/
First-of-its-Kind Therapy Approved to Prevent Hereditary Angioedema Attacks ... Shire announced that the Food and Drug Administration (FDA) has ...
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76 Shire's Takhzyro Gets FDA Nod for Hereditary Angioedema
https://www.zacks.com/stock/news/319550/shires-takhzyro-gets-fda-nod-for-hereditary-angioedema
Shire plc announced that the FDA has approved Takhzyro (lanadelumab-flyo) injection, for prophylaxis to prevent attacks of hereditary ...
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77 New England Journal of Medicine Publishes Phase 1b ...
https://markets.businessinsider.com/news/stocks/new-england-journal-of-medicine-publishes-phase-1b-results-for-shire-s-investigational-treatment-for-hereditary-angioedema-a-rare-genetic-disease-1001775974?miRedirects=1
... for Ongoing Phase 3 Trial Shire plc (LSE: SHP, NASDAQ: SHPG), ... ... for Shire's Investigational Treatment for Hereditary Angioedema, ...
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78 Hereditary Angioedema - CSL Behring
https://www.cslbehring.com/patients/find-your-disease/hereditary-angioedema
Hereditary Angioedema (HAE) is a rare hereditary disease that can cause attacks of swelling, and often pain, in specific parts of the body including the ...
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79 Lanadelumab - MMIT
https://info.mmitnetwork.com/hubfs/RJ%20Drug%20Alerts/RJH_2018_Pipeline_Review_Lanadelumab_FDA.pdf
Prophylaxis of Hereditary Angioedema (HAE) Attacks in patients 12 years ... Shire. Kallikrein inhibitor. Treat acute. HAE attacks. 12 years.
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80 New England Journal of Medicine Publishes Phase ... - Takeda
https://www.takedaleiras.com/newsroom/shire-news-releases/2017/y36ros/
New England Journal of Medicine Publishes Phase 1b Results for Shire's Investigational Treatment for Hereditary Angioedema, a Rare Genetic ...
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81 Management of Children With Hereditary Angioedema Due to ...
https://publications.aap.org/pediatrics/article/138/5/e20160575/60483/Management-of-Children-With-Hereditary-Angioedema
Hereditary angioedema (HAE) is a potentially life-threatening inherited disease characterized by attacks of skin swelling, severe abdominal ...
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82 Shire Reports Regulatory Milestones for Investigational ...
https://www.econotimes.com/Shire-Reports-Regulatory-Milestones-for-Investigational-Hereditary-Angioedema-HAE-Treatment-Lanadelumab-1228083
Shire Reports Regulatory Milestones for Investigational Hereditary Angioedema (HAE) Treatment Lanadelumab. Thu, Mar 29, 2018 6:01 AM. Increase text size.
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83 Hereditary angioedema | British Society for Immunology
https://www.immunology.org/public-information/bitesized-immunology/immune-dysfunction/hereditary-angioedema
Hereditary angioedema (HAE) affects approximately 1 in 50,000 of the population and does not show ethnic variation in frequency. HAE is inherited in an ...
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84 Hereditary Hemochromatosis Market to Expand at a Significant
https://www.openpr.com/news/2826475/hereditary-hemochromatosis-market-to-expand-at-a-significant
Some of the prominent names operating in the global hereditary angioedema market are Pharming Group NV, Shire plc, CSL Limited, Ionis ...
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85 Hereditary Angioedema (HAE) Quick Review - YouTube
https://www.youtube.com/watch?v=6C9dcCL795g
Medicosis Perfectionalis
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86 Hereditary angioedema HAE - Health Navigator NZ
https://www.healthnavigator.org.nz/health-a-z/h/hereditary-angioedema-hae/
Hereditary angioedema (HAE) is a rare, ongoing and potentially life-threatening condition that causes episodes of swelling in the tissues of different parts ...
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87 What is HAE? HAE Attack Info. | Ruconest® (C1 esterase ...
https://www.ruconest.com/what-is-hae/
Hereditary angioedema, also known as HAE, is a genetic condition that can cause severe swelling in different parts of your body. Hereditary angioedema (HAE) ...
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88 Hereditary Angioedema: Causes, Symptoms, and Treatment
https://www.ankitparakh.com/hereditary-angioedema-causes-symptoms-and-treatment/
Hereditary angioedema (HAE) is caused by a low level or improper function of a protein called the C1 inhibitor. There are three types of ...
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89 Back to business – PharmaLive (2022) - Mergelwind
https://mergelwind.com/article/back-to-business-pharmalive
In 2019 the company was in the midst of acquiring Shire; in 2020 Takeda was ... The hereditary angioedema brand Takhzyro recorded sales of $870 million in ...
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90 First Angioedema Treatment Center Opens at UC San Diego ...
https://health.ucsd.edu/news/releases/pages/2014-11-24-hereditary-angioedema-center.aspx
The best understood form of hereditary angioedema (HAE) is caused by a lack of a blood protein, known as a C1-inhibitor, which helps to prevent ...
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91 Angioedema, An Issue of Immunology and Allergy Clinics of ...
https://books.google.com/books?id=Si4tDwAAQBAJ&pg=PA617&lpg=PA617&dq=hereditary+angioedema+shire&source=bl&ots=GDbeHB0gya&sig=ACfU3U2C8JxfniGCqKO4k5632zYwuPoSYA&hl=en&sa=X&ved=2ahUKEwiZ7t2jjOD7AhWjElkFHdLsAZgQ6AF6BQjPAhAD
Patients with hereditary angioedema have benefited greatly from approval of novel ... He provides educational programs for Pharming, CSL Behring, and Shire.
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92 Urticaria and Angioedema: A Comprehensive Review of
https://books.google.com/books?id=BcWPDwAAQBAJ&pg=PA213&lpg=PA213&dq=hereditary+angioedema+shire&source=bl&ots=98c4OYPYcm&sig=ACfU3U0l7BdW-7e3qxk1ct0hI5OPtjD3zQ&hl=en&sa=X&ved=2ahUKEwiZ7t2jjOD7AhWjElkFHdLsAZgQ6AF6BQjOAhAD
First, icatibant acetate (Firazyr®, Shire HGT, Zug, Switzerland) [70, 71], ... In hereditary angioedema (HAE) with mutation in F12 gene (FXII-HAE), ...
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93 Urticaria, An Issue of Immunology and Allergy Clinics
https://books.google.com/books?id=Vh7QAgAAQBAJ&pg=PT48&lpg=PT48&dq=hereditary+angioedema+shire&source=bl&ots=ZKBIz8mqDG&sig=ACfU3U0E-7e0YWbhwv0shfOcP4cSxpS68w&hl=en&sa=X&ved=2ahUKEwiZ7t2jjOD7AhWjElkFHdLsAZgQ6AF6BQjCAhAD
Hereditary angioedema with normal C1inhibitor activity in women. Lancet. ... The author has received consultancyfeesfrom CSL Behring, Shire,and ViroPharma.
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94 Manual of Allergy and Clinical Immunology for Otolaryngologists
https://books.google.com/books?id=vj4qCgAAQBAJ&pg=PA172&lpg=PA172&dq=hereditary+angioedema+shire&source=bl&ots=63jek6X2ZY&sig=ACfU3U0M29RQloBy8P8WDhRSkPkahksq4g&hl=en&sa=X&ved=2ahUKEwiZ7t2jjOD7AhWjElkFHdLsAZgQ6AF6BQjGAhAD
... Icatibant (Firazyr, Shire Plc.) works by selectively blocking the bradykinin ... Diagnostic Criteria for Hereditary Angioedema with Normal C1-Inhibitor ...
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