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1 Genes involved in immune response/inflammation, IGF1 ...
https://pubmed.ncbi.nlm.nih.gov/15621218/
This includes genes encoding components of cytokine signalling, notably IL2RA and IL23R, as well as of innate immunity including autophagy (for example ATG16L1) ...
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2 The landscape of host genetic factors involved in immune ...
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-020-00790-x
Genetic determinants of response to viral infection. Results from our GWAS of antibody response phenotypes were dominated by signals in the HLA ...
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3 Genetics and Immune Disorders - Health Encyclopedia - URMC
https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=134&ContentID=122
Primary immunodeficiency disorders are present at birth. They are often inherited. This means they are linked to genes passed from one generation to another.
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4 Scientists Map Networks of Disease-Associated Immune Genes
https://www.ucsf.edu/news/2022/07/423281/scientists-map-networks-disease-associated-immune-genes
The scientists then studied the impact of disrupting these transcription factors on three immune genes known to play an important role in T cell ...
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5 Genetics and the Immune System
https://primaryimmune.org/news/genetics-and-immune-system
Problems in the genetic code cause primary immunodeficiency, and while we can't identify all the genes connected to the more than 400 ...
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6 Evolution of immune genes is associated with the Black Death
https://www.nature.com/articles/s41586-022-05349-x
The targeted immune genes were manually curated on the basis of their role in immune-related processes, and include innate immune receptors, key ...
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7 Researchers identify over 140 genes linked to immune system ...
https://www.sanger.ac.uk/news_item/researchers-identify-over-140-genes-linked-immune-system-regulation/
The researchers created and analysed 530 genetic variant mouse lines in the study. They found more than 140 genes involved in controlling the ...
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8 Immune genes are hotspots of shared positive selection ...
https://elifesciences.org/articles/41815
We show that functional pathways related to the immune system, recombination, lipid metabolism, and phototransduction are enriched for ...
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9 Genetics May Play Role in Determining Immunity to COVID-19
https://health.ucsd.edu/news/releases/Pages/2021-02-18-genetics-may-play-role-in-determining-immunity-to-covid-19.aspx
UC San Diego researchers report that individual immune response to SARS-CoV-2 may be limited by a set of variable genes that code for cell ...
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10 Black Death may have influenced evolution of genes involved ...
https://www.statnews.com/2022/10/19/black-death-may-have-influenced-evolution-of-genes-involved-in-immune-responses-study-finds/
Because Y. pestis and perhaps other pathogens select for gene variants that increase immune response, those genes are useful in an infectious ...
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11 Gene Lists - InnateDB
https://www.innatedb.com/redirect.do?go=resourcesGeneLists
The list of immunologically related genes in ImmPort is a collection of ~6,000 human genes, which was formed with the goal of retrieving all genes that have ...
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12 Transcriptional Profiles of Genes Related to Stress ... - Frontiers
https://www.frontiersin.org/articles/10.3389/fimmu.2021.639489/full
Transcriptional Profiles of Genes Related to Stress and Immune Response in Rainbow Trout (Oncorhynchus mykiss) Symptomatically or Asymptomatically Infected ...
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13 Genes and Immunity | Harvard Medical School
https://hms.harvard.edu/news/genes-immunity
“In general, there is stronger activation of some genes in people of African ancestry, in particular for a type of response in T helper 17 (Th17) ...
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14 Immune Response Genes in the Regulation of Mammalian ...
https://link.springer.com/chapter/10.1007/978-1-4684-9933-9_10
Immune response genes are operationally defined as antigen-specific genes that control the ability of an animal to raise an i immune response, humoral or ...
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15 Environment, not genes, plays starring role in human immune ...
https://med.stanford.edu/news/all-news/2015/01/environment-not-genes-plays-starring-role-in-immune-variation.html
Mark Davis and his colleagues have discovered that our environment, not our genes, play a greater factor in shaping the human immune system.
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16 Identification of innate immunity genes and pathways using a ...
https://www.pnas.org/doi/10.1073/pnas.0802405105
Using comparative genomics, we identified 11 genes and a protein interaction network that regulate innate immunity. Because these genes regulate multiple immune ...
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17 Genetic Analysis of Immune Disorders - Full Text View
https://clinicaltrials.gov/ct2/show/NCT00001467
Numerous rare disorders result from inherited or newly arising mutations in genes involved in the development and function of innate and adaptive immune ...
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18 Gene associated with better immune response, protection ...
https://www.ox.ac.uk/news/2022-10-13-gene-associated-better-immune-response-protection-after-covid-19-vaccination
The HLA gene helps the immune system distinguish the body's own proteins from foreign ones made by the likes of viruses and bacteria. The study ...
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19 How the Black Death changed our immune systems - Science
https://www.science.org/content/article/gene-helped-people-survive-black-death-come-haunt
But that difference—which determines whether the gene produces a full-size or truncated protein—had a big impact on immunity. People who ...
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20 Immune response determined by our genes, study shows
https://www.medicalnewstoday.com/articles/266746
Scientists say they have found evidence that suggests genetics play a role in immune response, affecting our ability to fight off disease.
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21 Exploration of Immune-Related Gene Expression in ...
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2782629
The enriched gene ontology functions for the survival-associated IRGs were mainly related to the immune system, including immunocyte ...
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22 The role of innate immune genes in Alzheimer's disease
https://journals.lww.com/co-neurology/Fulltext/2021/04000/The_role_of_innate_immune_genes_in_Alzheimer_s.13.aspx
Genome-wide association studies (GWAS) have identified many Alzheimer's disease risk genes related to immune response and microglia including the phagocytic ...
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23 Disorders of the Immune System | Johns Hopkins Medicine
https://www.hopkinsmedicine.org/health/conditions-and-diseases/disorders-of-the-immune-system
If you are born with certain genes, your immune system may react to substances in ... what causes autoimmune diseases, but many factors seem to be involved.
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24 Genetics play a significant role in immunity - ScienceDaily
https://www.sciencedaily.com/releases/2017/01/170105082755.htm
Nearly three quarters of immune traits are influenced by genes, new research from King's College London reveals. advertisement ...
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25 COVID-19 Host Genetics & Immune Response Profiling
https://www.illumina.com/areas-of-interest/microbiology/infectious-diseases/host-genetics-immune-response.html
It is crucial to identify genetic variants linked to COVID-19 disease severity, and study immune response differences such as inflammatory cytokine, T cell, and ...
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26 20 Rapid evolution of innate immune response genes
https://academic.oup.com/book/6244/chapter/149891067
The opportunity for arms-race evolution between host and pathogens is one reason why genes involved in immune functions are often rapidly evolving.
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27 Disease Development - Autoimmune Disease
https://pathology.jhu.edu/autoimmune/development
The genes confer what is called "predisposition" or genetic susceptibility. The immune system becomes dysregulated and provides the tools for executing the ...
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28 Immune-related key genes as potential diagnostic biomarkers
https://www.dovepress.com/identification-of-immune-related-key-genes-as-potential-diagnostic-bio-peer-reviewed-fulltext-article-JIR
Hub gene analysis can identify genes that occupy core regulatory positions in PPI networks. We took the top 20 hub genes in the PPI networks of ...
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29 Cancer Cells' Unexpected Genetic Tricks for Evading the ...
https://www.hhmi.org/news/cancer-cells-unexpected-genetic-tricks-evading-immune-system
... mutated tumor suppressor genes that can prevent the immune system ... Hundreds of cancer-linked genes play a different role in causing ...
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30 Researchers identify gene associated with strong immune ...
https://www.news-medical.net/news/20221018/Researchers-identify-gene-associated-with-strong-immune-response-after-COVID-19-vaccination.aspx
The HLA gene helps the immune system distinguish the body's own proteins from foreign ones made by the likes of viruses and bacteria. The study ...
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31 Identification of key genes related to immune cells in patients ...
https://atm.amegroups.com/article/view/98408/html
Weighted gene co-expression network analysis (WGCNA) was used to determine the networks that are associated with the differentially distributed ...
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32 Researchers identify over 140 genes ... - King's College London
https://www.kcl.ac.uk/news/researchers-identify-over-140-genes-linked-to-immune-system-regulation
The researchers created and analysed 530 genetic variant mouse lines in the study. They found more than 140 genes involved in controlling the ...
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33 Functional genetics in inborn errors of immunity
https://www.futuremedicine.com/doi/10.2217/frd-2020-0003
Individuals with defects in genes that encode for molecules involved in complement system also suffer from increased susceptibility to infection ...
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34 Are Autoimmune Diseases Genetic? - GoodRx
https://www.goodrx.com/health-topic/autoimmune/genetic-causes
An autoimmune disease (AID) is a health condition where your body's immune system attacks its own cells and tissues. And though we don't know ...
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35 Study maps immune system genes involved in re - EurekAlert!
https://www.eurekalert.org/news-releases/929820
The results suggest that certain genetic variants found more frequently in the resistant subjects are associated with more efficient activation ...
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36 Immunological Genome Project
https://www.immgen.org/

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37 Genes Involved in Immune System Regulation Identified
https://www.technologynetworks.com/genomics/news/immune-system-regulating-genes-are-identified-313791
Researchers have mapped the most important genes for controlling T helper cells, and identified new regulatory genes that could help ...
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38 Differential immune gene response in gills, skin, and spleen of ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218630
› plosone › article › journal.pone....
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39 Altered expression of genes related to innate antifungal ...
https://www.tandfonline.com/doi/full/10.1080/21505594.2021.1903212
Its expression in cells involved in innate and adaptive immunity is related to anti- and proinflammatory functions, signaling an important role in inflammatory, ...
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40 Genetic variation in 1253 immune and inflammation genes ...
https://ashpublications.org/blood/article/110/13/4455/103230/Genetic-variation-in-1253-immune-and-inflammation
Smaller-scale evaluations suggest that common genetic variation in candidate genes related to immune function may predispose to the development of ...
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41 Discovery of gene associated with 20 autoimmune diseases ...
https://theconversation.com/discovery-of-gene-associated-with-20-autoimmune-diseases-leads-to-promising-drug-trials-131957
Over the past decade, many studies investigating the genetics of autoimmunity have found a common feature: a particular gene, called TYK2. This ...
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42 Sharks show novel evolution of immune, cancer-related genes
https://news.cornell.edu/stories/2017/01/sharks-show-novel-evolution-immune-cancer-related-genes
Two shark immune genes, legumain and Bag1,stand out.Both of these genes have counterparts in humans, where their overexpression is known to be ...
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43 Scientists map key genes regulating immune cells - CORDIS
https://cordis.europa.eu/article/id/124826-scientists-map-key-genes-regulating-immune-cells
The researchers' creation of an atlas of the most important genes involved in regulating Th cell immune response will help to deepen ...
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44 Research Continues to Link Genes to Autoimmune Disease
https://www.ifm.org/news-insights/ai-research-continues-link-genes-autoimmune-disease/
A number of confirmed gene coding regions predispose an individual to autoimmunity; for instance, the human leukocyte antigen (HLA) region is associated with ...
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45 Genetic associations of T cell cancer immune response ...
https://jitc.bmj.com/content/8/2/e000336
IDO1:rs10108662 is the most significant SNP associated with survival, with the variant genotype correlated with higher death risk. IDO1 encodes indoleamine-2,3- ...
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46 Neanderthals boosted our immune system
https://www.mpg.de/9819763/neanderthal-genes-immune-system
The archaic-like variants are associated with an increase in the activity of the TLR genes and with greater reactivity to pathogens. Although ...
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47 IRGM gene: MedlinePlus Genetics
https://medlineplus.gov/genetics/gene/irgm/
The IRGM gene provides instructions for making a protein that plays an important role in the immune system. This protein is involved in a ...
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48 The factors that most affect our immune system - Institut Pasteur
https://www.pasteur.fr/en/research-journal/news/factors-most-affect-our-immune-system
Immune variation and differences in terms of sex and age · Genetic variations and risk of disease · Contenus liés · Subscribe to our newsletter.
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49 Gene therapy - Mayo Clinic
https://www.mayoclinic.org/tests-procedures/gene-therapy/about/pac-20384619
Several types of cancer have been linked to problems with the p53 gene. ... Doctors could use gene therapy to train your immune system to ...
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50 Human Gene Set: IMMUNE_SYSTEM_PROCESS - GSEA
https://www.gsea-msigdb.org/gsea/msigdb/cards/IMMUNE_SYSTEM_PROCESS
Genes annotated by the GO term GO:0002376. Any process involved in the development or functioning of the immune system, an organismal system for calibrated ...
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51 Genetic testing in patients with a suspected primary ...
https://www.uptodate.com/contents/genetic-testing-in-patients-with-a-suspected-primary-immunodeficiency-or-autoinflammatory-syndrome
Some autoinflammatory syndromes, particularly those caused by activating variants in genes involved in the innate immune system, ...
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52 Why Bad Immunity Genes Survive | NSF
https://www.nsf.gov/news/news_summ.jsp?cntn_id=123040
Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system ...
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53 Genes | Free Full-Text | Transcriptome Meta-Analysis ... - MDPI
https://www.mdpi.com/2073-4425/10/12/1005
In sepsis, the host immune response is depressed and unable to cope with ... Our criteria are to unravel sepsis-associated signature genes from gene ...
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54 Gene Expression and Signaling in the Immune System | CSHL
https://meetings.cshl.edu/meetings.aspx?meet=IMMUNE&year=22
We are looking forward to a broad-based meeting, and abstracts are welcomed on all scientific topics related to immune system gene expression and signaling.
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55 The role of host genetics in the immune response to SARS ...
https://onlinelibrary.wiley.com/doi/full/10.1111/imr.12897
Such genetic association studies and the insights they provide are critical to identifying the HLA alleles that may be associated with ...
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56 Candidate Genes of Allergic Dermatitis Are Associated with ...
https://www.hindawi.com/journals/jhe/2022/8745722/
In addition, ssGSEA and ImmPort database were used to identify AD-related immune response abnormalities. In this study, a total of 60 common genes were ...
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57 It's not just the germs — it's also the genes
https://www.asbmb.org/asbmb-today/science/111520/it-s-not-just-the-germs-it-s-also-the-genes
And yet again, facets of the immune system appear to be involved — notably, a set of signaling molecules called interferons.
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58 Immune system‑associated genes increase malignant ...
https://www.spandidos-publications.com/10.3892/ijo.2020.4998
Immune system‑associated genes increase malignant progression and can be used to predict clinical outcome in patients with hepatocellular ...
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59 How Genes Affecting the Immune System - Indus Health Plus
https://www.indushealthplus.com/genetic-dna-testing/how-to-improve-immunity.html
A Major part of your immune system is influenced by your genes. By understanding your genes you can increase the immunity and prevent diseases.
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60 Immune System Genomics | Broad Institute
https://www.broadinstitute.org/immunology/immune-system-genomics
... studies of the human immune system than ever before possible. ... This revolution in the genetic and epigenetic analysis of human disease is quickly ...
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61 Genetic variants and MIS-C in children
https://answers.childrenshospital.org/mis-c-genetic-variants/
Tipping the immune system toward inflammation ... The affected genes are involved in biochemical pathways in the body that are related to ...
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62 Ancient DNA shows people with certain genes were more ...
https://news.uchicago.edu/story/ancient-dna-shows-people-certain-genes-were-more-likely-survive-black-death
“Having the functional version of the gene appears to create an advantage, likely by enhancing the ability of our immune system to sense the ...
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63 Gene therapy offers potential cure to children born without an ...
https://newsroom.ucla.edu/releases/gene-therapy-for-children-born-without-immune-system
... has restored immune function in more than 95% of patients in ... and were considered to be related to routine procedures performed in ...
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64 Immunity is in your genes: What your DNA can tell you about ...
https://endodna.com/2020/06/21/immunity-is-in-your-genes-what-your-dna-can-tell-you-about-your-immune-health/
DNA variations are linked to different immune responses, according to scientific studies. · Depending on your unique genotype, you could be ...
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65 immune system diseases Genetics & Genomics News
https://www.genomeweb.com/disease-areas/immune-system-diseases
Researchers profiled DNA sequences in hundreds of ancient Europeans to find immune gene- and autoimmune disease-related variants under selection during the ...
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66 Genes that Aided Black Death Survival Linked to Autoimmunity
https://www.the-scientist.com/news-opinion/genes-that-aided-black-death-survival-linked-to-autoimmunity-70662
“A hyperactive immune system may have been great in the past but in the environment today it might not be as helpful,” study coauthor Hendrik ...
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67 DNA Methylation patterns of immune response-related genes ...
https://www.scielo.br/j/bor/a/34YhKTPhSWG3HVmZPKBMfdv/?lang=en
Therefore, the present study aimed to identify methylation patterns in the immune-related genes of patients with IERR. We hypothesize that the epigenetic status ...
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68 A genetic cause of autoimmune disease
https://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/learn-about-genomics/dna-base/collection1/lrba-gene-and-autoimmune-disease
Variants in the LRBA gene can have a devastating effect on our immune system, potentially leading to autoimmune disease.
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69 Loneliness May Warp Our Genes, And Our Immune Systems
https://www.npr.org/sections/health-shots/2015/11/29/457255876/loneliness-may-warp-our-genes-and-our-immune-systems
Loneliness has been linked to everything from heart disease to Alzheimer's disease. Depression is common among the lonely.
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70 Excavating the genes that help tumours escape the immune ...
https://cancergrandchallenges.org/news/excavating-genes-help-tumours-escape-immune-system
Tumours in different tissues escape the immune system through multiple mechanisms. For example, some lung and blood cancers are known to hide ...
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71 Deregulation of Immune Response Genes in Patients With ...
https://www.gastrojournal.org/article/S0016-5085(14)01142-1/abstract
Patients with Epstein-Barr virus–associated gastric carcinoma (EBVaGC) have a better prognosis than those with gastric cancer not associated ...
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72 Genes link autism and immunity | Spectrum
https://www.spectrumnews.org/news/genes-link-autism-and-immunity/
Based on samples collected from dozens of children, California researchers found a group of 11 genes, all related to the innate immune system ― ...
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73 Immune system - Wikipedia
https://en.wikipedia.org/wiki/Immune_system
B cells are involved in the humoral immune response, whereas T cells are involved in cell-mediated immune response. Killer T cells only recognize antigens ...
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74 Immune Cell Gene Signatures for Profiling ... - AACR Journals
https://aacrjournals.org/cancerimmunolres/article/6/11/1388/468810/Immune-Cell-Gene-Signatures-for-Profiling-the
For visualization of the results, genes pertaining to cell subsets ... Despite an established association between the immune system and survival in melanoma ...
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75 Selection of Human Immune-Related Genes Was Driven by ...
https://neurosciencenews.com/immune-disease-black-death-21678/
“Having the functional version of the gene, appears to create an advantage, likely by enhancing the ability of our immune system to sense the ...
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76 Genetic traits of Black Death survivors linked to autoimmune ...
https://www.theguardian.com/society/2022/oct/19/gene-black-death-survivors-linked-autoimmune-diseases
“A hyperactive immune system may have been great in the past but in the environment today it might not be as helpful.”.
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77 What Happens When the Immune System Does Not Work ...
https://www.chop.edu/centers-programs/vaccine-education-center/human-immune-system/what-happens-when-immune-system-does-not-work-properly
Genetic variations · Severe combined immune deficiency (SCID), which results from problems with T cell development. · X-linked agammaglobulinemia, which results ...
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78 Genes in immune pathways associated with abnormal white ...
https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/genes-in-immune-pathways-associated-with-abnormal-white-matter-integrity-in-firstepisode-and-treatmentnaive-patients-with-schizophrenia/FCDADCC4A82E7E1043DB8B3A7D8E08F9
Functional enrichment analysis for genes in each module revealed that the yellow module was enriched with highly co-expressed, innate immune response genes.
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79 Genetic Architecture of Adaptive Immune System Identifies ...
https://www.babraham.ac.uk/sites/default/files/media/files/30332657.pdf
LARP1B and SP4 Are Involved in B Cell Differentiation. sjKREC excision circles allow quantification of newly formed. B cells at the DNA level.
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80 Genetic Variance is Key to Individual Immune Response
https://www.genengnews.com/topics/omics/genetic-variance-is-key-to-individual-immune-response/
Genetic differences in immune response demonstrate interaction of genetics and environment linked to disease risk.
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81 Your Immune System Is Made, Not Born - Scientific American
https://www.scientificamerican.com/article/your-immune-system-is-made-not-born/
Genetics had almost no effect on how well individuals responded to the flu vaccine, judged by antibodies produced against the injected material.
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82 Do the Genes of the Innate Immune Response Contribute to ...
https://www.karger.com/Article/Fulltext/365195
Drosophila is being used to investigate the mechanisms involved in neurodegeneration, and all genomic studies on this issue have generated gene ...
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83 Genome-wide Analysis of Immune System Genes by ...
https://journals.aai.org/jimmunol/article/190/11/5578/87156/Genome-wide-Analysis-of-Immune-System-Genes-by
The immune system is our central defense against bacterial and viral pathogens. As such, misregulation of certain genes that are critical ...
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84 Do Your Genes Know What's Making You Sick? - The Atlantic
https://www.theatlantic.com/health/archive/2022/01/immune-test-mysterious-infection/621158/
Testing for immune-system changes, rather than for the presence of a ... of that gene, which is involved in an inflammatory response against ...
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85 Genetics and Immune Disorders - Spectrum Health Lakeland
https://www.spectrumhealthlakeland.org/lakeland-ear-nose-and-throat/ent-health-library/Content/134/122/
Genes also affect the way the immune system works or how it responds to threats. Primary immunodeficiency disorders are present at birth.
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86 What Is the Genetic Influence on the Severity of COVID 19?
https://www.medscape.com/viewarticle/984716
Their research found genetic variants related to immune response that were associated with susceptibility to infection and progression to ...
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87 What makes our immune system work? - Science Node
https://sciencenode.org/feature/Human%20vaccine%20project.php
In a new study from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system: the genes encoding the ...
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88 On DNA Day, A Salute to the “Magic” Genes That Give Us a ...
https://www.amgen.com/stories/2020/04/on-dna-day-a-salute-to-the-magic-genes-that-give-us-a-fighting-chance-against-viruses
There is a constant war between our immune system and the microbial world, and this special ability of our T cells and B cells has evolved to ...
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89 Understanding How COVID-19 Vaccines Work - CDC
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/how-they-work.html
To trigger an immune response, many vaccines put a weakened or ... viral vectors have also been studied for gene therapy, to treat cancer, and for molecular ...
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90 Immune System (for Parents) - Nemours KidsHealth
https://kidshealth.org/en/parents/immune.html
How Does the Immune System Work? · Innate immunity: Everyone is born with innate (or natural) immunity, a type of general protection. · Adaptive immunity: ...
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91 What Is Cancer? - NCI
https://www.cancer.gov/about-cancer/understanding/what-is-cancer
These changes are also called genetic changes. A DNA change can cause genes involved in normal cell growth to become oncogenes. Unlike normal ...
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92 Insights into the Genetic Basis of Autoimmune Disease
https://www.youtube.com/watch?v=OO1m2x9qXdE
Apr 20, 2016
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93 Gene Mutation May Explain Brain Cell Plaque Buildup in ...
https://nyulangone.org/news/gene-mutation-may-explain-brain-cell-plaque-buildup-alzheimers-disease
The buildup of such clumps, also called plaque, sets off an immune response that can kill brain cells and may lead to the dementia associated ...
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94 The gene hunt to explain why some young, healthy people die ...
https://www.rockefeller.edu/news/28008-gene-hunt-explain-young-healthy-people-die-covid-19/
Severe pneumonia caused by influenza, for example, has been linked to errors in genes that regulate production of immune signaling proteins, ...
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95 The Immune System - CancerQuest
https://www.cancerquest.org/cancer-biology/immune-system
Of importance to us: The genetic changes that make normal cells into cancer cells ... The exact steps involved in the generation of an immune response are ...
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