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1 Developmental Regulation of bicoid mRNA Stability Is ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC110668/
Thus, bicoid mRNA is localised by random active transport and anterior anchoring. Super-resolution imaging reveals that bicoid mRNA forms 110–120 nm particles ...
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2 bicoid mRNA localises to the Drosophila oocyte ... - eLife
https://elifesciences.org/articles/17537
The localisation of bicoid mRNA depends on its microtubule-independent anchoring at the oocyte anterior.
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3 Bicoid mRNA diffusion as a mechanism of morphogenesis in ...
https://www.sciencedirect.com/science/article/pii/S1631069114002182
During the first 14 nuclear divisions of the developing embryo, bicoid mRNA of maternal origin is translated into protein in the ribosomes and accumulates near ...
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4 bcd - bicoid - WikiGenes
https://www.wikigenes.org/e/gene/e/40830.html
Drosophila bicoid mRNA is synthesized in the nurse cells and transported to the oocyte where microtubules and Exuperantia protein mediate localization to ...
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5 Protein encoded by the exuperantia gene is concentrated at ...
http://genesdev.cshlp.org/content/5/12b/2455.full.pdf
Formation of the anteroposterior gradient of the bicoid (bcd) protein morphogen in Drosophila ... After synthesis in the nurse cells, bcd mRNA is trans-.
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6 Bicoid - Society for Developmental Biology
https://www.sdbonline.org/sites/fly/segment/bicoid1.htm
Its mRNA remains localized at the anterior tip of the oocyte and later in the early embryonic stages. Maternal bcd transcription is regulated by ...
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7 Bicoid mRNA Localization in the Anterior Pole of the Oocyte ...
https://learninglink.oup.com/access/content/barresi-12e-student-resources/barresi-12e-further-development-9-5-bicoid-mrna-localization-in-the-anterior-pole-of-the-oocyte
(A) bicoid mRNA shows a steep gradient (here seen as red to blue) across the anterior portion of the oocyte. (B) When the mRNA is translated, the Bicoid protein ...
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8 Seeing is believing: the Bicoid protein reveals its path
https://hereditasjournal.biomedcentral.com/articles/10.1186/s41065-018-0067-3
1b), followed by synthesis of the protein based on the mRNA gradient (Fig. 1c). One report showed that the mRNA briefly enters the yolk at ...
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9 The anterior determinant bicoid of Drosophila is a derived Hox ...
https://www.pnas.org/doi/10.1073/pnas.96.7.3786
The bicoid mRNA is transferred into the oocyte and becomes localized in the anterior pole region of the egg. After egg deposition and translation of the ...
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10 No significant regulation of bicoid mRNA by Pumilio or Nanos ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194865
Anterior segmentation is controlled by Bcd [1, 2], which is translated from maternally synthesized bcd mRNA that is localized to the ...
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11 3.1: The Curious Case of Bicoid: Models for Making a Gradient ...
https://bio.libretexts.org/Bookshelves/Evolutionary_Developmental_Biology/Evolutionary_Developmental_Biology_(Rivera)/03%3A_Cleavage_and_Gastrulation/3.1%3A_The_Curious_Case_of_Bicoid%3A%09Models_for_Making_a_Gradient-A_Model_Emerges
ARTS model (Active mRNA, Transport, Synthesis): The cytoskeleton actively transports Bicoid mRNA to form an mRNA gradient that gets readout ...
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12 63_wickens_etal_1996.pdf - Biochemistry | UW-Madison
https://biochem.wisc.edu/sites/default/files/people/judith-kimble/pdfs/1990s/63_wickens_etal_1996.pdf
At the anterior, newly synthesized Bicoid protein represses caudal mRNA and ultimately activates zygotic transcription of hunchback; at the posterior, Nanos ...
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13 RNA–RNA interaction is required for the formation of specific ...
https://www.embopress.org/doi/10.1093/emboj/16.7.1751
The formation of the anterior pattern of the Drosophila embryo is dependent on the localization of the mRNA of the morphogen Bicoid (bcd) to the anterior ...
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14 The formation of the embryonic axes in Drosophila
https://acsjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1097-0142%2819930515%2971%3A10%3C3189%3A%3AAID-CNCR2820711048%3E3.0.CO%3B2-Y
protein, the functional product of the bicoid gene. This protein is produced at the anterior pole, using the. mRNA as a template.
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15 Gratuitous mRNA localization in the Drosophila oocyte
http://dev.biologists.org/content/develop/121/9/3013.full.pdf
bicoid (bcd), oskar (osk) and gurken (grk) mRNAs. bcd and osk mRNAs are localized to the ... Drosophila oocyte, K10 mRNA is synthesized in nurse cells.
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16 In Vivo Analysis of Drosophila bicoid mRNA ... - ResearchGate
https://www.researchgate.net/publication/11879823_In_Vivo_Analysis_of_Drosophila_bicoid_mRNA_Localization_Reveals_a_Novel_Microtubule-Dependent_Axis_Specification_Pathway
Drosophila bicoid mRNA is synthesized in the nurse cells and transported to the oocyte where microtubules and Exuperantia protein mediate ...
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17 DNA Specificity of the Bicoid Activator Protein Is Determined ...
https://brentlab.fredhutch.org/content/dam/stripe/brent/files/11.pdf
bicoid mRNA is synthesized in nurse cells during oogenesis and transported into the developing oocyte where it is localized in the anterior (Ber- leth et al., ...
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18 Restricted Distribution of mRNA Produced from a Single ...
https://rupress.org/jcb/article-pdf/119/5/1063/1063836/1063.pdf
the distributions of three different mRNAs produced by sin- gle nuclei in hybrid myotubes and ... have been implicated in the transport of bicoid mRNA in.
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19 Formation of the bicoid morphogen gradient: an mRNA ...
https://journals.biologists.com/dev/article/136/4/605/65444/Formation-of-the-bicoid-morphogen-gradient-an-mRNA
The Bicoid (Bcd) protein gradient is generally believed to be established in pre-blastoderm Drosophila embryos by the diffusion of Bcd ...
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20 Chapter 21 Flashcards - Quizlet
https://quizlet.com/174051183/chapter-21-flash-cards/
bicoid mRNA is translated at the anterior pole of the fertilized egg. Which body part develops in regions with a low concentration of Bicoid protein?
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21 FlyBase Reference Report: Cha et al., 2001, Cell 106(1): 35--46
http://flybase.org/reports/FBrf0137189.html
Drosophila bicoid mRNA is synthesized in the nurse cells and transported to the oocyte where microtubules and Exuperantia protein mediate localization to ...
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22 A Function for Kinesin I in the Posterior Transport of oskar ...
https://www.science.org/doi/10.1126/science.289.5487.2120
In Drosophila oocytes, the anterior localization of bicoid mRNA and the posterior localization of oskar mRNA are key events in establishing the ...
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23 The Bicoid Morphogen Gradient Matures - Devoto Lab
http://sdevoto.web.wesleyan.edu/218/readings/ephrussi_StJohnston2004.pdf
review recent results on bicoid mRNA localization and ... During oogenesis, bicoid mRNA is produced in the nurse cells and transported in a ...
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24 bicoid mRNA localization in Drosophila late ...
https://search.proquest.com/openview/e1c508e40453ee616911cc6d27729f0c/1?pq-origsite=gscholar&cbl=18750
Localization of bicoid (bcd) mRNA (RNA), the anterior determinant, is required to establish a morphogenetic gradient of Bcd protein in the early embryo, which ...
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25 The Formation of the Bicoid Morphogen Gradient Requires ...
https://tglab.princeton.edu/wp-content/uploads/2010/12/journal.pbio_.1000596.pdf
We determine that .90% of all bicoid mRNA is continuously present within the ... gradient formation via constant anterior protein synthesis, coupled.
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26 Bicoid | The Embryo Project Encyclopedia
https://embryo.asu.edu/pages/bicoid
The gradient is established in the anterior pole by the production of bicoid protein from bicoid mRNA, and extends greater than sixty ...
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27 Absence of bicoid mRNA from a Drosophila ... - StudySmarter
https://www.studysmarter.us/textbooks/biology/campbell-biology-11th/regulation-of-gene-expression/q18-7tyu-absence-of-bicoid-mrna-from-a-drosophila-egg-leads-/
› ... › Ch 18
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28 Different genetic requirements for anterior RNA ... - jstor
https://www.jstor.org/stable/2361558
maternally synthesized mRNA known previously to be local- ized to the anterior cortex of both the oocyte and the early embryo is the bicoid mRNA whose ...
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29 Synthetic deconstruction of hunchback regulation by Bicoid
https://www.biorxiv.org/content/10.1101/2021.09.06.459125v2.full
This high variability was consistent with smFISH data measuring the variability of hb mRNA amounts in nuclei (Little et al., 2013) and reflected ...
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30 Localization, anchoring and translational control of oskar ...
https://www.tandfonline.com/doi/pdf/10.4161/fly.3.1.7751
bicoid and nanos mRNA during Drosophila oogenesis ... osk mRNA is produced in the nurse cells and transported into the.
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31 Mechanism of Dimerization of Bicoid mRNA
https://www.jbc.org/article/S0021-9258(20)75041-6/fulltext
Mechanism of Dimerization of Bicoid mRNA. INITIATION AND STABILIZATION*. Céline Wagner ... Plasmid Construction and RNA Synthesis.
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32 bicoid mRNA localises to the Drosophila ... - ScienceOpen
https://www.scienceopen.com/document_file/bc9652cc-96d0-4483-8f7b-ac8dfb2a2b45/PubMedCentral/bc9652cc-96d0-4483-8f7b-ac8dfb2a2b45.pdf
By contrast, osk mRNA is translated when it reaches the ... another motor protein called Dynein moves bicoid mRNA along microtubules.
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33 the bicoid gene in Drosophila embryos - YouTube
https://www.youtube.com/watch?v=sCyf3uoHRag
Jul 20, 2019
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34 The cytoskeleton and mRNA localization
https://www.einsteinmed.edu/labs/robert-singer/publications/SL9201.pdf
proteins are synthesized in specific cellular regions. The spatial information on the mRNA may be ... bicoid mRNA in the anterior region of Drosq2ika em-.
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35 MCB 141 midterm answ
https://mcb.berkeley.edu/courses/mcb141/exams/Midterm1/keys/141Midterm1_2008_key.pdf
Into some freshly laid mutant embryos (laid by females homozygous mutant for a bicoid lack of function mutation) you inject synthetic bicoid mRNA into the ...
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36 Eukaryotic gene expression can be regulated at any stage
http://www.lamission.edu/lifesciences/lecturenote/Chapter%2018%20-%20Lecture/Chapter%2018%20-%20Lecture.ppt
No RNA made. Active. repressor. mRNA. Protein. DNA. DNA. mRNA 5 ... high): abundant lac mRNA synthesized ... Bicoid mRNA in mature unfertilized egg.
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37 Changes in bicoid mRNA anchoring highlight conserved ...
https://europepmc.org/articles/PMC2581475
Intracellular mRNA localization directs protein synthesis to particular subcellular domains to establish embryonic polarity in a variety of organisms.
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38 Maternal effect genes | Utkal University
https://utkaluniversity.ac.in/wp-content/uploads/2022/06/Maternal-effect-genes.pdf
performed mRNAs and proteins that are synthesized and laid down in the egg by the mother ... Bicoid mRNA contain a sequence in its 3'UTR that interact with.
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39 mRNA diffusion explains protein gradients in Drosophila early ...
https://hal.archives-ouvertes.fr/hal-00591235/document
In this model, we consider that bicoid mRNA diffuses along the antero-posterior axis of the embryo and the protein is produced in.
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40 Distinguishing direct from indirect roles for bicoid mRNA ...
https://www.hubrecht.eu/app/uploads/2018/02/Rabouille_2010_Distinguishing-direct-from-indirect-roles-for-bicoid-mRNA-localization-factors.pdf
Translation of bicoid (bcd) mRNA that is localized at the anterior of the newly fertilized embryo results in a morphogenetic protein gradient that specifies ...
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41 Localization of bicoid mRNA in Late Oocytes Is ... - CORE
https://core.ac.uk/download/pdf/82780249.pdf
investigation of microtubule-dependent mRNA localiza- tion. Synthesized in the ovarian nurse cells, bcd mRNA enters the oocyte through cytoplasmic bridges ...
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42 Mathematical approaches in studying bicoid gene
https://link.springer.com/content/pdf/10.1007/s40484-015-0058-6.pdf
During the oogenesis bcd mRNA which is synthesised in the nurse cells is localised at the anterior end of the egg. [4]. After fertilization, translation of ...
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43 Seeing is believing: the Bicoid protein reveals its path
https://d-nb.info/1172383278/34
1b), followed by synthesis of the protein based on the mRNA gradient. (Fig. 1c). One report showed that the mRNA briefly en- ters the yolk at nuclear cycle 4 [ ...
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44 mRNA poly(A)-tail changes specified by deadenylation ...
https://dash.harvard.edu/bitstream/handle/1/29002511/4988829.pdf?sequence=1&isAllowed=y
Moreover, appending synthetic poly(A) tails of increasing lengths to the bicoid mRNA promotes the translation of this mRNA, ...
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45 Microtubule-based motor-mediated mRNA localization in ...
https://portlandpress.com/biochemsoctrans/article/39/5/1197/86358/Microtubule-based-motor-mediated-mRNA-localization
mRNAs are synthesized in the nurse cell nuclei. ... Localization of bicoid mRNA in late oocytes is maintained by continual active transport.
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46 Weil TT et al. (2008), Changes in bicoid mRNA anchoring ...
https://www.xenbase.org/literature/article.do?method=display&articleId=38148
Weil TT , Parton R , Davis I , Gavis ER . ... Intracellular mRNA localization directs protein synthesis to particular subcellular domains to ...
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47 Answered: In a fly egg, the nurse cells are… | bartleby
https://www.bartleby.com/questions-and-answers/in-a-fly-egg-the-nurse-cells-are-killed-before-they-can-produce-bicoid-mrna.-what-will-happen-group-/ed56c3f3-a5e5-4d9e-be22-569fb238b24a
Find answers to questions asked by students like you. Show more Q&Aadd. Q: The bicoid protein in a larval fly is produced by mRNA that originally came ...
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48 1.2 n&v MH NEW - The University of Utah
https://bastiani.biology.utah.edu/courses/3230/db%20lecture/Lectures/FlyMaternal/BicoidLocalizationNature07.pdf
efficient synthesis of part of a naturally occur- ... The authors devised their synthetic strategy1 ... for instance, the bicoid mRNA is moved to the.
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49 bicoid RNA localization requires the trans-Golgi network - KOPS
https://kops.uni-konstanz.de/bitstream/handle/123456789/47202/Cai_2-6dbl8e7biwvv7.pdf?sequence=1&isAllowed=y
Background: The formation of the bicoid (bcd) mRNA gradient is a crucial step for Bcd protein ... SDD model, synthesis, diffusion and uniform degradation;.
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50 Modelling the Bicoid gradient
https://personal.math.ubc.ca/~nagata/sci1/bicoid.pdf
synthesis of Bicoid protein at the anterior pole of the embryo (from an mRNA source that is either point-like or graded), diffusion from.
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51 bicoid RNA localization requires specific binding of an ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA185449167&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=00280836&p=HRCA&sw=w
bicoid messenger RNA localizes to the anterior of the Drosophila egg, where it is translated to form a morphogen gradient of Bicoid protein that patterns ...
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52 RNA world (article) | Natural selection - Khan Academy
https://www.khanacademy.org/science/ap-biology/natural-selection/origins-of-life-on-earth/a/rna-world
Once the egg is fertilized, the bicoid mRNA is translated to make a protein. Bicoid protein switches on genes that make head-making proteins and switches ...
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53 Bicoid mrna localization Related Genes And Facts | Bosterbio
https://www.bosterbio.com/pathways/bicoid-mrna-localization
Quite a number of genes have been found to play important roles in Bicoid Mrna Localization, such as ATN1, ATP6V0A1, CYP4V2, EGF, EGFR, MCAT, Pabpc1, RFC1, RFC2 ...
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54 Patterning Development in the Early Embryo: The Role of Bicoid
https://www.ibiology.org/development-and-stem-cells/bicoid/
00:03:03.25 like bicoid arises, you have a localized RNA, synthesis, and then movement 00:03:10.19 of the protein. And most of our knowledge and all the ...
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55 Absence of bicoid mRNA from a Drosophila egg leads to the ...
https://www.numerade.com/questions/absence-of-bicoid-mrna-from-a-drosophila-egg-leads-to-the-absence-of-anterior-larval-body-parts-and-/
However, it doesn't need to be made in this cell. In fact, chances are that this is from the mother creating the sill rather than, Ah, something that trance ...
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56 Homeotic protein bicoid - Wikipedia
https://en.wikipedia.org/wiki/Homeotic_protein_bicoid
Dubuis and Thomas Gregor. (Bottom) Bicoid–GFP protein (green) and FISH-labeled bicoid mRNA (red) in the anterior tip of a fixed transgenic Drosophila embryo.
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57 Explore Drosophila development and embryonic protein ...
http://www.dnaftb.org/37/problem.html
The A/P axis is set up by a protein called BICOID that is expressed in a anterior-to-posterior gradient. What will happen to an embryo that doesn't have any ...
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58 Essential Developmental Biology - Page 234 - Google Books Result
https://books.google.com/books?id=SwtQEAAAQBAJ&pg=PA234&lpg=PA234&dq=where+is+bicoid+mrna+synthesized&source=bl&ots=YUJtLv2i0m&sig=ACfU3U1mK43Q8bCV9sVkaZYKxuCZkQlWKw&hl=en&sa=X&ved=2ahUKEwi6jbiDkuH7AhX0iP0HHU7xBg0Q6AF6BAgvEAM
Furthermore, eggs lacking bicoid can be rescued towards a normal phenotype by injection of bicoid mRNA. The position at which the injection is made ...
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59 Gene Control, Second Edition - Page 339 - Google Books Result
https://books.google.com/books?id=uKDHBgAAQBAJ&pg=PA339&lpg=PA339&dq=where+is+bicoid+mrna+synthesized&source=bl&ots=MJaypbMV_2&sig=ACfU3U15Qh3yH9PZpPISLKhustWb24FeFQ&hl=en&sa=X&ved=2ahUKEwi6jbiDkuH7AhX0iP0HHU7xBg0Q6AF6BAgyEAM
Interestingly, computer models have now been produced which can predict the ... Unlike the Bicoid mRNA however, the Caudal mRNA is uniformly distributed ...
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60 Building Brains: An Introduction to Neural Development
https://books.google.com/books?id=yec5DwAAQBAJ&pg=PA81&lpg=PA81&dq=where+is+bicoid+mrna+synthesized&source=bl&ots=Ey40jaJG12&sig=ACfU3U0QazTwOU1Q_CdwmmLApjKDf-c-lA&hl=en&sa=X&ved=2ahUKEwi6jbiDkuH7AhX0iP0HHU7xBg0Q6AF6BAgxEAM
A major morphogen is encoded by the bicoid gene; bicoid mRNA is synthesized in the mother's nurse cells and then deposited in the maturing egg, ...
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61 Introduction to Genetics: A Molecular Approach
https://books.google.com/books?id=byoWBAAAQBAJ&pg=PA381&lpg=PA381&dq=where+is+bicoid+mrna+synthesized&source=bl&ots=ct3sW9tHJS&sig=ACfU3U2rmClo-GwPN37aZyiq5k-a_v6FNw&hl=en&sa=X&ved=2ahUKEwi6jbiDkuH7AhX0iP0HHU7xBg0Q6AF6BAgwEAM
Introduction to Genetics | Brown | Figure F1833 anterior posterior bicoid mRNA is injected into the egg Bicoid proteins are synthesized in the anterior ...
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