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Google Keyword Rankings for : alpha thalassemia immune system
1
Thalassemia: Complications and Treatment - CDC
https://www.cdc.gov/ncbddd/thalassemia/treatment.html
Because of this, people with thalassemia are said to be “immunocompromised,” which means that some of the body's defenses against infection aren't working. When ...
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https://www.cdc.gov/ncbddd/thalassemia/treatment.html
Because of this, people with thalassemia are said to be “immunocompromised,” which means that some of the body's defenses against infection aren't working. When ...
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2
Alpha thalassemia: MedlinePlus Genetics
https://medlineplus.gov/genetics/condition/alpha-thalassemia/
In people with the characteristic features of alpha thalassemia, a reduction in the amount of hemoglobin prevents enough oxygen from reaching the body's tissues ...
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https://medlineplus.gov/genetics/condition/alpha-thalassemia/
In people with the characteristic features of alpha thalassemia, a reduction in the amount of hemoglobin prevents enough oxygen from reaching the body's tissues ...
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3
Alpha Thalassemia - NORD (National Organization for Rare ...
https://rarediseases.org/rare-diseases/alpha-thalassemia/
Alpha thalassemia is a general term for a group of inherited blood disorders characterized by reduced or absent production of alpha-globin subunits, resulting ...
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https://rarediseases.org/rare-diseases/alpha-thalassemia/
Alpha thalassemia is a general term for a group of inherited blood disorders characterized by reduced or absent production of alpha-globin subunits, resulting ...
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4
Alpha-thalassemia - About the Disease
https://rarediseases.info.nih.gov/diseases/621/alpha-thalassemia/
Alpha-thalassemia is a blood disorder that reduces the body's production of hemoglobin. Affected people have anemia, which can cause pale ...
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https://rarediseases.info.nih.gov/diseases/621/alpha-thalassemia/
Alpha-thalassemia is a blood disorder that reduces the body's production of hemoglobin. Affected people have anemia, which can cause pale ...
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5
Thalassemia - Symptoms and causes - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/thalassemia/symptoms-causes/syc-20354995
Hemoglobin molecules are made of chains called alpha and beta chains that can be affected by mutations. In thalassemia, the production of either ...
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https://www.mayoclinic.org/diseases-conditions/thalassemia/symptoms-causes/syc-20354995
Hemoglobin molecules are made of chains called alpha and beta chains that can be affected by mutations. In thalassemia, the production of either ...
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6
Q&A with Dr. Richard Ward – Thalassemia and Infections
https://www.thalassemia.org/qa-dr-richard-ward-thalassemia-infections/
Research has shown that high amounts of iron overload in your body reduces the levels of some of the proteins of the innate immune system and so ...
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https://www.thalassemia.org/qa-dr-richard-ward-thalassemia-infections/
Research has shown that high amounts of iron overload in your body reduces the levels of some of the proteins of the innate immune system and so ...
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7
Alpha Thalassemia (for Parents) - Nemours KidsHealth
https://kidshealth.org/en/parents/thalassemias.html
Alpha thalassemia is a blood disorder in which the body has a problem producing alpha globin, a component of hemoglobin, the protein in red blood cells that ...
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https://kidshealth.org/en/parents/thalassemias.html
Alpha thalassemia is a blood disorder in which the body has a problem producing alpha globin, a component of hemoglobin, the protein in red blood cells that ...
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8
What is thalassaemia? | Causes and Types - Patient.info
https://patient.info/allergies-blood-immune/thalassaemia-leaflet
Alpha plus thalassaemia trait. This means that you have one missing alpha haemoglobin gene. (Normally there are four of these genes.) This trait ...
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https://patient.info/allergies-blood-immune/thalassaemia-leaflet
Alpha plus thalassaemia trait. This means that you have one missing alpha haemoglobin gene. (Normally there are four of these genes.) This trait ...
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9
Alpha Thalassemia Trait - St. Jude Children's Research Hospital
https://www.stjude.org/treatment/disease/sickle-cell-disease/diagnosing-sickle-cell/alpha-thalassemia-trait.html
Alpha thalassemia affects the amount of hemoglobin in the red blood cells. · Missing one alpha thalassemia gene (silent carriers): (αα/α-), a silent carrier does ...
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https://www.stjude.org/treatment/disease/sickle-cell-disease/diagnosing-sickle-cell/alpha-thalassemia-trait.html
Alpha thalassemia affects the amount of hemoglobin in the red blood cells. · Missing one alpha thalassemia gene (silent carriers): (αα/α-), a silent carrier does ...
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10
Thalassaemia carriers - NHS
https://www.nhs.uk/conditions/thalassaemia/carriers/
If you're a carrier of thalassaemia, it means you carry one of the faulty genes that cause thalassaemia, but you do not have thalassaemia yourself.
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https://www.nhs.uk/conditions/thalassaemia/carriers/
If you're a carrier of thalassaemia, it means you carry one of the faulty genes that cause thalassaemia, but you do not have thalassaemia yourself.
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11
Pathophysiology of thalassemia - UpToDate
https://www.uptodate.com/contents/pathophysiology-of-thalassemia
Alpha and beta thalassemia are inherited hemoglobinopathies in which impaired production of one type of globin chain (alpha chains in alpha ...
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https://www.uptodate.com/contents/pathophysiology-of-thalassemia
Alpha and beta thalassemia are inherited hemoglobinopathies in which impaired production of one type of globin chain (alpha chains in alpha ...
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12
Intrauterine Therapy for Alpha Thalassemia Major
https://fetus.ucsf.edu/intrauterine-therapy-alpha-thalassemia-major/
The immune system of a developing fetus has unique features that make stem cell transplant safer before birth than after birth. This is particularly true when ...
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https://fetus.ucsf.edu/intrauterine-therapy-alpha-thalassemia-major/
The immune system of a developing fetus has unique features that make stem cell transplant safer before birth than after birth. This is particularly true when ...
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13
What to Know About Thalassemia and COVID-19
https://www.verywellhealth.com/thalassemia-and-coronavirus-covid-19-risks-and-complications-5186553
There are four types of alpha thalassemia, and two main types of beta ... hormones that stimulate the immune system to fight infections.
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https://www.verywellhealth.com/thalassemia-and-coronavirus-covid-19-risks-and-complications-5186553
There are four types of alpha thalassemia, and two main types of beta ... hormones that stimulate the immune system to fight infections.
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14
Signs of thalassemia - Ada Health
https://ada.com/conditions/thalassemia/
A person who inherits one or two faulty alpha genes will have alpha thalassemia trait, meaning they are a thalassemia carrier, but do not ...
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https://ada.com/conditions/thalassemia/
A person who inherits one or two faulty alpha genes will have alpha thalassemia trait, meaning they are a thalassemia carrier, but do not ...
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15
Evaluation of immune system in patients with transfusion ...
https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.871
Thalassemia syndromes are the most common hemoglobinopathy globally related to blood transfusion and iron overload in the body. Splenectomy, ...
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https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.871
Thalassemia syndromes are the most common hemoglobinopathy globally related to blood transfusion and iron overload in the body. Splenectomy, ...
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16
COVID-19 and Thalassemia - Hematology.org
https://www.hematology.org/covid-19/covid-19-and-thalassemia
Thalassemia patients, especially young adults/adults, have a chronic condition which may be associated with several co-morbidities linked to the underlying ...
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https://www.hematology.org/covid-19/covid-19-and-thalassemia
Thalassemia patients, especially young adults/adults, have a chronic condition which may be associated with several co-morbidities linked to the underlying ...
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17
Thalassemia: Types, symptoms, and treatment
https://www.medicalnewstoday.com/articles/263489
People with hemoglobin H, a form of alpha thalassemia, are more likely to ... a reaction where the person's immune system tries to destroy the new blood.
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https://www.medicalnewstoday.com/articles/263489
People with hemoglobin H, a form of alpha thalassemia, are more likely to ... a reaction where the person's immune system tries to destroy the new blood.
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18
Thalassaemia - Better Health Channel
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/thalassaemia
Alpha-thalassaemia involves genetic changes in two genes (HBA1 and HBA2). Beta-thalassaemia involves changes in one gene (HBB). Alpha-thalassaemia is more ...
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https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/thalassaemia
Alpha-thalassaemia involves genetic changes in two genes (HBA1 and HBA2). Beta-thalassaemia involves changes in one gene (HBB). Alpha-thalassaemia is more ...
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19
Thalassemia Symptoms & Treatment | UPMC - Pittsburgh PA
https://www.upmc.com/services/sickle-cell/conditions/thalassemia
Types of Thalassemia. Alpha thalassemia and beta thalassemia represent the two main types of the disorder. The alpha or beta designation depends on which gene ...
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https://www.upmc.com/services/sickle-cell/conditions/thalassemia
Types of Thalassemia. Alpha thalassemia and beta thalassemia represent the two main types of the disorder. The alpha or beta designation depends on which gene ...
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20
Thalassemia: Causes, Symptoms, Diagnosis, and Treatment
https://www.healthline.com/health/thalassemia
Thalassemia minor is a less serious form of the disorder. There are two main forms of thalassemia that are more serious. In alpha thalassemia, at least one of ...
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https://www.healthline.com/health/thalassemia
Thalassemia minor is a less serious form of the disorder. There are two main forms of thalassemia that are more serious. In alpha thalassemia, at least one of ...
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21
Alpha-thalassemia - References | BMJ Best Practice US
https://bestpractice.bmj.com/topics/en-us/250/references
There are at least 4 different and distinct alpha-thalassemias: silent carrier (1 affected alpha-globin gene), alpha-thalassemia trait (2 affected ...
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https://bestpractice.bmj.com/topics/en-us/250/references
There are at least 4 different and distinct alpha-thalassemias: silent carrier (1 affected alpha-globin gene), alpha-thalassemia trait (2 affected ...
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22
Review Molecular basis of α-thalassemia - ScienceDirect.com
https://www.sciencedirect.com/science/article/pii/S1079979617301493
α-Thalassemia is an inherited, autosomal recessive, disorder characterized by a microcytic hypochromic anemia. It is one of the most common monogenic gene ...
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https://www.sciencedirect.com/science/article/pii/S1079979617301493
α-Thalassemia is an inherited, autosomal recessive, disorder characterized by a microcytic hypochromic anemia. It is one of the most common monogenic gene ...
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23
Immune responses in beta-thalassaemia: heme oxygenase 1 ...
https://www.nature.com/articles/s41598-020-67346-2
β-Thalassaemia disease is thought to be impaired immune response against various type of infections. According to studies on melioidosis, β- ...
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https://www.nature.com/articles/s41598-020-67346-2
β-Thalassaemia disease is thought to be impaired immune response against various type of infections. According to studies on melioidosis, β- ...
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24
Thalassemia - familydoctor.org
https://familydoctor.org/condition/thalassemia/
Alpha thalassemia: Missing or mutated genes related to the alpha globin protein. · Beta thalassemia (also called Cooley anemia): Gene defects ...
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https://familydoctor.org/condition/thalassemia/
Alpha thalassemia: Missing or mutated genes related to the alpha globin protein. · Beta thalassemia (also called Cooley anemia): Gene defects ...
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25
Thalassemia - MDPI
https://mdpi-res.com/d_attachment/ijms/ijms-22-09677/article_deploy/ijms-22-09677-v2.pdf?version=1631073937
of immune system cells resulting from chronic inflammation ... The imbalance in the relative quantity of α-globin and β-globin chains and ...
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https://mdpi-res.com/d_attachment/ijms/ijms-22-09677/article_deploy/ijms-22-09677-v2.pdf?version=1631073937
of immune system cells resulting from chronic inflammation ... The imbalance in the relative quantity of α-globin and β-globin chains and ...
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26
Higher Hospitalization Rate for Lower Airway Infection in ...
https://www.frontiersin.org/articles/10.3389/fped.2020.574014/full
In adults, hemoglobin comprises four protein chains (two α and two β globin chains) that are assembled into a heterotetramer. In α-thalassemia ...
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https://www.frontiersin.org/articles/10.3389/fped.2020.574014/full
In adults, hemoglobin comprises four protein chains (two α and two β globin chains) that are assembled into a heterotetramer. In α-thalassemia ...
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27
Alpha Thalassemia - Family Practice Notebook
https://fpnotebook.com/hemeonc/hemoglobin/AlphThlsm.htm
Alpha Thalassemia Intermedia. Mild to moderate Hemolytic Anemia ; Alpha Thalassemia Major. Non-Immune Hydrops Fetalis in utero (fatal) ...
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https://fpnotebook.com/hemeonc/hemoglobin/AlphThlsm.htm
Alpha Thalassemia Intermedia. Mild to moderate Hemolytic Anemia ; Alpha Thalassemia Major. Non-Immune Hydrops Fetalis in utero (fatal) ...
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28
Thalassemia - Stanford Medicine Children's Health
https://www.stanfordchildrens.org/en/service/stem-cell-transplantation/conditions/thalassemia
The main forms of thalassemia are alpha- (defect in alpha-globin gene production ... when their blood and immune systems are functioning at healthy levels.
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https://www.stanfordchildrens.org/en/service/stem-cell-transplantation/conditions/thalassemia
The main forms of thalassemia are alpha- (defect in alpha-globin gene production ... when their blood and immune systems are functioning at healthy levels.
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29
Pathomechanisms of Immunological Disturbances in β ... - MDPI
https://www.mdpi.com/1422-0067/22/18/9677/htm
β-thalassemia itself results in a constant immune stimulation [8]. Reduced synthesis of β-globin chains translates into an excess amount of α-chains which ...
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https://www.mdpi.com/1422-0067/22/18/9677/htm
β-thalassemia itself results in a constant immune stimulation [8]. Reduced synthesis of β-globin chains translates into an excess amount of α-chains which ...
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30
α+-Thalassemia protects children against disease caused by ...
https://www.pnas.org/doi/10.1073/pnas.94.26.14736
The mechanism of the remarkable protective effect of α+-thalassemia against severe childhood disease remains unclear but must encompass the clear interaction ...
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https://www.pnas.org/doi/10.1073/pnas.94.26.14736
The mechanism of the remarkable protective effect of α+-thalassemia against severe childhood disease remains unclear but must encompass the clear interaction ...
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31
Alpha thalassemia major—new mutations, intrauterine ...
https://ashpublications.org/hematology/article/2009/1/35/19887/Alpha-thalassemia-major-new-mutations-intrauterine
Alpha thalassemia disorders are a group of hereditary anemias caused by absent or decreased production of the α chain of hemoglobin. They are ...
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https://ashpublications.org/hematology/article/2009/1/35/19887/Alpha-thalassemia-major-new-mutations-intrauterine
Alpha thalassemia disorders are a group of hereditary anemias caused by absent or decreased production of the α chain of hemoglobin. They are ...
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32
α+-Thalassemia Protects against Anemia Associated with ...
https://academic.oup.com/jid/article/198/3/401/837242
Background. In hospital-based studies, α+-thalassemia has been found to protect against severe, life-threatening falciparum malaria. α+-Thalassemia does not ...
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https://academic.oup.com/jid/article/198/3/401/837242
Background. In hospital-based studies, α+-thalassemia has been found to protect against severe, life-threatening falciparum malaria. α+-Thalassemia does not ...
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33
Blood Disease Protects Against Malaria In An Unexpected ...
https://www.sciencedaily.com/releases/2008/03/080318094553.htm
Children with an inherited blood disorder called alpha thalassemia make unusually small red blood cells that mostly cause a mild form of ...
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https://www.sciencedaily.com/releases/2008/03/080318094553.htm
Children with an inherited blood disorder called alpha thalassemia make unusually small red blood cells that mostly cause a mild form of ...
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34
Hydrops Fetalis | Boston Children's Hospital
https://www.childrenshospital.org/conditions/hydrops-fetalis
Hydrops fetalis is sometimes used as a synonym for homozygous alpha thalassemia, a lethal or life-threatening disease of mid- and late fetal development ...
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https://www.childrenshospital.org/conditions/hydrops-fetalis
Hydrops fetalis is sometimes used as a synonym for homozygous alpha thalassemia, a lethal or life-threatening disease of mid- and late fetal development ...
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35
Alpha thalassemia - Classes | NCBO BioPortal - SNOMED CT
http://purl.bioontology.org/ontology/SNOMEDCT/68913001
Finding of blood, lymphatics and immune system ... Alpha thalassaemia syndrome. Alpha thalassemia syndrome. alpha thalassaemia.
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http://purl.bioontology.org/ontology/SNOMEDCT/68913001
Finding of blood, lymphatics and immune system ... Alpha thalassaemia syndrome. Alpha thalassemia syndrome. alpha thalassaemia.
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36
The Role of Immune System in Thalassemia Major
https://pdfs.semanticscholar.org/5d55/ce6b9e175580b17a8d2c866f946089fc22cd.pdf
On the other hand, higher levels of TNF-α and IL-1β, IL-6, IL-8, and C-reactive protein proinflammatory cytokines have been observed in the ...
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https://pdfs.semanticscholar.org/5d55/ce6b9e175580b17a8d2c866f946089fc22cd.pdf
On the other hand, higher levels of TNF-α and IL-1β, IL-6, IL-8, and C-reactive protein proinflammatory cytokines have been observed in the ...
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37
Clinical Guidance on COVID- 19 Vaccines for People with ...
http://www.bccdc.ca/Health-Info-Site/Documents/COVID-19_vaccine/Thalassemia_Clinical_Guidance.pdf
Some people with thalassemia are at a higher risk for severe COVID-19 infections ... there is a potential for blunted immune response in individuals who are ...
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http://www.bccdc.ca/Health-Info-Site/Documents/COVID-19_vaccine/Thalassemia_Clinical_Guidance.pdf
Some people with thalassemia are at a higher risk for severe COVID-19 infections ... there is a potential for blunted immune response in individuals who are ...
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38
Treatment for Beta Thalassemia - WebMD
https://www.webmd.com/a-to-z-guides/treat-beta-thalassemia
If you or your child has a blood disorder called beta thalassemia, the goal ... Your spleen helps your immune system get rid of bacteria and ...
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https://www.webmd.com/a-to-z-guides/treat-beta-thalassemia
If you or your child has a blood disorder called beta thalassemia, the goal ... Your spleen helps your immune system get rid of bacteria and ...
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39
In Utero Hematopoietic Stem Cell Transplantation for Alpha ...
https://clinicaltrials.gov/ct2/show/NCT02986698
Alpha Thalassemia Major Hemoglobinopathy; With Thalassemia ... the fetus takes advantage of the developing fetal immune system to induce ...
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https://clinicaltrials.gov/ct2/show/NCT02986698
Alpha Thalassemia Major Hemoglobinopathy; With Thalassemia ... the fetus takes advantage of the developing fetal immune system to induce ...
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40
Vitamin and mineral supplementation for β-thalassemia during ...
https://www.future-science.com/doi/10.2144/fsoa-2020-0110
Aim: Low levels of immune-related micronutrients have been identified in β-thalassemia samples. Moreover, the excess amount of iron, ...
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https://www.future-science.com/doi/10.2144/fsoa-2020-0110
Aim: Low levels of immune-related micronutrients have been identified in β-thalassemia samples. Moreover, the excess amount of iron, ...
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41
Intrauterine Therapy for Alpha Thalassemia Major
https://thalassemia.com/services-intrauterine-therapy.aspx
Hemoglobin Bart's (Hydrops Fetalis or Alpha Thalassemia Major) is a devastating, usually fatal disease. It is common in many ethnic groups, including China, ...
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https://thalassemia.com/services-intrauterine-therapy.aspx
Hemoglobin Bart's (Hydrops Fetalis or Alpha Thalassemia Major) is a devastating, usually fatal disease. It is common in many ethnic groups, including China, ...
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42
Haemoglobinopathies and resistance to malaria
https://www.tandfonline.com/doi/pdf/10.1179/135100003225002998
mild malaria in children carrying α-thalassaemia.10,11 One explanation for these observations is ... posed that the immune response to malaria parasites is.
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https://www.tandfonline.com/doi/pdf/10.1179/135100003225002998
mild malaria in children carrying α-thalassaemia.10,11 One explanation for these observations is ... posed that the immune response to malaria parasites is.
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43
What is Alpha and Beta Thalassemia? - Anavara
https://anavara.com/treatment/alpha-and-beta-thalassemia/
Haemoglobins function as the body's-manufactured proteins carrying oxygen to and fro to the human body system. Though an uncommon disease, thalassemia mostly ...
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https://anavara.com/treatment/alpha-and-beta-thalassemia/
Haemoglobins function as the body's-manufactured proteins carrying oxygen to and fro to the human body system. Though an uncommon disease, thalassemia mostly ...
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44
Alpha-Thalassemia (A-THAL) - MalaCards
https://www.malacards.org/card/alpha_thalassemia_2
Deletion of both copies of each of the two alpha-globin genes causes alpha(0)- thalassemia, also known as homozygous alpha thalassemia. Due to the complete ...
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https://www.malacards.org/card/alpha_thalassemia_2
Deletion of both copies of each of the two alpha-globin genes causes alpha(0)- thalassemia, also known as homozygous alpha thalassemia. Due to the complete ...
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45
Alteration of monocyte subsets and their functions in ...
https://link.springer.com/article/10.1007/s12185-022-03484-9
The primary endpoint was monocyte-derived TNF-α expression. ... Azizi H. The role of immune system in thalassemia major: a narrative review.
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https://link.springer.com/article/10.1007/s12185-022-03484-9
The primary endpoint was monocyte-derived TNF-α expression. ... Azizi H. The role of immune system in thalassemia major: a narrative review.
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46
Thalassemia - CDHO
https://www.cdho.org/Advisories/CDHO_Factsheet_Thalassemia.pdf
[which is also known as α thalassemia major, hemoglobin Bart hydrops fetalis, ... damage, and various immune system abnormalities.
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https://www.cdho.org/Advisories/CDHO_Factsheet_Thalassemia.pdf
[which is also known as α thalassemia major, hemoglobin Bart hydrops fetalis, ... damage, and various immune system abnormalities.
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47
Thalassemia and immune system dysfunction-review article
https://www.researchgate.net/publication/233728849_Thalassemia_and_immune_system_dysfunction-review_article
Immune defects in β-TM comprise the innate and the adaptive immune systems including aberrations in cell-mediated immunity, neutrophil ...
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https://www.researchgate.net/publication/233728849_Thalassemia_and_immune_system_dysfunction-review_article
Immune defects in β-TM comprise the innate and the adaptive immune systems including aberrations in cell-mediated immunity, neutrophil ...
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48
Malaria and Thalassemia in the Mediterranean Basin
https://www.ashclinicalnews.org/features/blood-beyond-borders-malaria-thalassemia-mediterranean-basin/
The proposed mechanisms through which the alpha and beta hemoglobin mutations guard against malaria are categorized as either immune-related or ...
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https://www.ashclinicalnews.org/features/blood-beyond-borders-malaria-thalassemia-mediterranean-basin/
The proposed mechanisms through which the alpha and beta hemoglobin mutations guard against malaria are categorized as either immune-related or ...
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49
A Case of Concurrent Sickle Cell Trait, Alpha Thalassemia ...
https://www.longdom.org/open-access/a-case-of-concurrent-sickle-cell-trait-alpha-thalassemia-and-g6pd-deficiency-in-a-pediatric-patient-61494.html
Alpha thalassemia is a blood disorder that reduces the production of haemoglobin. G6PD deficiency is a genetic disorder that most often affects males. It ...
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https://www.longdom.org/open-access/a-case-of-concurrent-sickle-cell-trait-alpha-thalassemia-and-g6pd-deficiency-in-a-pediatric-patient-61494.html
Alpha thalassemia is a blood disorder that reduces the production of haemoglobin. G6PD deficiency is a genetic disorder that most often affects males. It ...
→ Check Latest Keyword Rankings ←
50
Stem Cell Transplant for Sickle Cell Disease or Thalassemia ...
https://www.research.chop.edu/stem-cell-transplant-for-sickle-cell-disease-or-thalassemia-major
... years to 25 years of age with sickle cell disease or beta thalassemia major, ... time it takes for the new stem cells to establish a new immune system.
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https://www.research.chop.edu/stem-cell-transplant-for-sickle-cell-disease-or-thalassemia-major
... years to 25 years of age with sickle cell disease or beta thalassemia major, ... time it takes for the new stem cells to establish a new immune system.
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51
Thalassaemia: An Inherited Blood Disorder - HealthXchange.sg
https://www.healthxchange.sg/children/baby-0-24-months/thalassaemia-inherited-blood-disorder
In thalassaemia, there is a problem in the formation of alpha-globin or beta-globin chains. This leads to your red blood cells not being formed correctly ...
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https://www.healthxchange.sg/children/baby-0-24-months/thalassaemia-inherited-blood-disorder
In thalassaemia, there is a problem in the formation of alpha-globin or beta-globin chains. This leads to your red blood cells not being formed correctly ...
→ Check Latest Keyword Rankings ←
52
Alpha thalassemia Related Genes And Facts | Bosterbio
https://www.bosterbio.com/diseases/alpha-thalassemia
Information and facts about alpha-thalassemia. ... Gene Conversion, Immune Response, Interphase, Localization, Meiosis, Methylation, Mitosis, Pathogenesis, ...
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https://www.bosterbio.com/diseases/alpha-thalassemia
Information and facts about alpha-thalassemia. ... Gene Conversion, Immune Response, Interphase, Localization, Meiosis, Methylation, Mitosis, Pathogenesis, ...
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53
Thalassaemia
https://www.stgeorges.nhs.uk/wp-content/uploads/2015/03/Thalassaemia-information-from-patient-co-uk.pdf
So, the blood system goes into overproduction mode which can cause more ... The main types of thalassaemia are called alpha thalassaemia and beta ...
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https://www.stgeorges.nhs.uk/wp-content/uploads/2015/03/Thalassaemia-information-from-patient-co-uk.pdf
So, the blood system goes into overproduction mode which can cause more ... The main types of thalassaemia are called alpha thalassaemia and beta ...
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54
THE COVID–19 PANDEMIC AND HAEMOGLOBIN DISORDERS
https://thalassaemia.org.cy/wp-content/uploads/2020/03/COVID-19-pandemic-and-haemoglobin-disorders_V2.pdf
Angastiniotis Michael, Paediatrician, Medical Advisor at the Thalassaemia ... immune systems, older people, and those with long-term conditions like ...
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https://thalassaemia.org.cy/wp-content/uploads/2020/03/COVID-19-pandemic-and-haemoglobin-disorders_V2.pdf
Angastiniotis Michael, Paediatrician, Medical Advisor at the Thalassaemia ... immune systems, older people, and those with long-term conditions like ...
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55
Thalassemia Benefits - News Medical
https://www.news-medical.net/health/Thalassemia-Benefits.aspx
According to the research, children with mild alpha-thalassemia have natural protection against the anemia associated with malaria.
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https://www.news-medical.net/health/Thalassemia-Benefits.aspx
According to the research, children with mild alpha-thalassemia have natural protection against the anemia associated with malaria.
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56
Alpha thalassaemia screen | Sonic Genetics
https://www.sonicgenetics.com.au/our-tests/all-tests/alpha-thalassaemia-screen/
There are two alpha globin genes (HBA1 and HBA2) which produce proteins which contribute to haemoglobin. Patients normally have four copies of the HBA gene, ...
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https://www.sonicgenetics.com.au/our-tests/all-tests/alpha-thalassaemia-screen/
There are two alpha globin genes (HBA1 and HBA2) which produce proteins which contribute to haemoglobin. Patients normally have four copies of the HBA gene, ...
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57
Whole-exome sequencing analysis of amniotic fluid cells in 5...
https://journals.lww.com/md-journal/Fulltext/2022/11250/Whole_exome_sequencing_analysis_of_amniotic_fluid.19.aspx
Abnormalities of the innate immune system associated with thalassemia were reported including reduced absorption and phagocytic ability of ...
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https://journals.lww.com/md-journal/Fulltext/2022/11250/Whole_exome_sequencing_analysis_of_amniotic_fluid.19.aspx
Abnormalities of the innate immune system associated with thalassemia were reported including reduced absorption and phagocytic ability of ...
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58
Information for people with thalassemia - COVID-19 Vaccine
https://www.gov.nl.ca/covid-19/vaccine/clinically-extremely-vulnerable/thalassemia/
However, the way the vaccines work means that there is a strong chance that your immune system will learn to protect you, to some extent, ...
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https://www.gov.nl.ca/covid-19/vaccine/clinically-extremely-vulnerable/thalassemia/
However, the way the vaccines work means that there is a strong chance that your immune system will learn to protect you, to some extent, ...
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59
Beta-Thalassemia minor and SARS-CoV-2, prevalence ...
https://www.medrxiv.org/content/10.1101/2022.07.25.22278009v2.full
Beta-thalassemia patients involve three cell protection systems during erythropoiesis ... In β-thalassemia, iron control (and therefore the control of heme) is a ...
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https://www.medrxiv.org/content/10.1101/2022.07.25.22278009v2.full
Beta-thalassemia patients involve three cell protection systems during erythropoiesis ... In β-thalassemia, iron control (and therefore the control of heme) is a ...
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60
Streamlined Assay Improves Prenatal Detection of Alpha ...
https://www.labmedica.com/molecular-diagnostics/articles/294782837/streamlined-assay-improves-prenatal-detection-of-alpha-thalassemia.html
Alpha-Thalassemia is a group of recessively inherited hemoglobin (Hb) disorders that result from decreased or absent synthesis of α-globin ...
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https://www.labmedica.com/molecular-diagnostics/articles/294782837/streamlined-assay-improves-prenatal-detection-of-alpha-thalassemia.html
Alpha-Thalassemia is a group of recessively inherited hemoglobin (Hb) disorders that result from decreased or absent synthesis of α-globin ...
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61
Immunologic Abnormalities in β-Thalassemia
https://www.walshmedicalmedia.com/open-access/immunologic-abnormalities-in-thalassemia-2155-9864.1000224.pdf
State of immune system in β-thalassemia. The first information about ... Decrease of synthesis β-globin chains leads to an excess of α-chains.
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https://www.walshmedicalmedia.com/open-access/immunologic-abnormalities-in-thalassemia-2155-9864.1000224.pdf
State of immune system in β-thalassemia. The first information about ... Decrease of synthesis β-globin chains leads to an excess of α-chains.
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62
Novel genetic therapeutic approaches for modulating the ...
https://www.spandidos-publications.com/10.3892/br.2020.1355
Using multiplex PCR, α-globin gene deletions were identified. Female β-thalassemia patients carrying α-globin wild type genotype (αα/αα) had ...
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https://www.spandidos-publications.com/10.3892/br.2020.1355
Using multiplex PCR, α-globin gene deletions were identified. Female β-thalassemia patients carrying α-globin wild type genotype (αα/αα) had ...
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63
About SCD | SCTPN - Sickle Cell/Thalassemia Patients Network
https://sctpn.net/about-scd/
α-thalassemia is a quantitative disorder. Red blood cells (RBC) break down (hemolysis) every day, and the bone marrow is unable to produce enough RBCs to ...
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https://sctpn.net/about-scd/
α-thalassemia is a quantitative disorder. Red blood cells (RBC) break down (hemolysis) every day, and the bone marrow is unable to produce enough RBCs to ...
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64
Pediatric Blood & Bone Marrow Conditions We Treat
https://www.nicklauschildrens.org/medical-services/cancer-institute/conditions-we-treat
Alpha thalassemia is an abnormality in the production of alpha chains which ... where the body's own immune system begins to attack important tissues and ...
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https://www.nicklauschildrens.org/medical-services/cancer-institute/conditions-we-treat
Alpha thalassemia is an abnormality in the production of alpha chains which ... where the body's own immune system begins to attack important tissues and ...
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65
SYnAbs innovative monoclonal antibodies targeting ...
https://www.synabs.be/2022/01/13/synabs-innovative-monoclonal-antibodies-targeting-hemoglobinopathia-diseases/
Alpha-thalassemia is very common. It mainly affects populations from Asia (Cambodia, Laos, Burma, Thailand in particular), in its intermediate ...
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https://www.synabs.be/2022/01/13/synabs-innovative-monoclonal-antibodies-targeting-hemoglobinopathia-diseases/
Alpha-thalassemia is very common. It mainly affects populations from Asia (Cambodia, Laos, Burma, Thailand in particular), in its intermediate ...
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66
Biochemical and Hematological Study with the ... - Gale
https://go.gale.com/ps/i.do?id=GALE%7CA573094537&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=09737510&p=AONE&sw=w
Seventy patients involved 48 beta thalassemia patients and 22 alpha thalassemia ... There are many disorders in the immune system of [beta]-thalassemia ...
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https://go.gale.com/ps/i.do?id=GALE%7CA573094537&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=09737510&p=AONE&sw=w
Seventy patients involved 48 beta thalassemia patients and 22 alpha thalassemia ... There are many disorders in the immune system of [beta]-thalassemia ...
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67
Alpha-thalassemia - Human Phenotype Ontology
https://hpo.jax.org/app/browse/disease/ORPHA:846
Alpha-thalassemia is an inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture ...
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https://hpo.jax.org/app/browse/disease/ORPHA:846
Alpha-thalassemia is an inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture ...
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68
Alpha Thalassemia Genetics Question Made Simple - YouTube
https://www.youtube.com/watch?v=_HGoPTjvES8
Dr Aishwarya Kelkar Medical Lectures
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https://www.youtube.com/watch?v=_HGoPTjvES8
Dr Aishwarya Kelkar Medical Lectures
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69
Update on the Diagnosis and Management of Thalassemia
https://www.hematologyandoncology.net/archives/january-2014/update-on-the-diagnosis-and-management-of-thalassemia/
Loss of 3 genes causes mild to severe anemia that can be exacerbated by fever and/or various infections. Loss of all 4 α-globin genes, which occurs most ...
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https://www.hematologyandoncology.net/archives/january-2014/update-on-the-diagnosis-and-management-of-thalassemia/
Loss of 3 genes causes mild to severe anemia that can be exacerbated by fever and/or various infections. Loss of all 4 α-globin genes, which occurs most ...
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70
Pediatric Severe Combined Immunodeficiency (SCID)
https://childrensnational.org/visit/conditions-and-treatments/blood-marrow/severe-combined-immunodeficiency
The disease causes a child to have very weak immune system. The best treatment for this disease is a bone marrow transplant. Parents of children with SCID ...
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https://childrensnational.org/visit/conditions-and-treatments/blood-marrow/severe-combined-immunodeficiency
The disease causes a child to have very weak immune system. The best treatment for this disease is a bone marrow transplant. Parents of children with SCID ...
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71
Alpha Thalassemia Market to Reflect Impressive Expansion ...
https://www.medgadget.com/2018/09/alpha-thalassemia-market-to-reflect-impressive-expansion-during-2018-2023-growing-at-gagr-of-8-8-asserts-mrfr-unleashing-market-insights-till-2023.html
Alpha thalassemia is a blood disorder that causes abnormal production of hemoglobin in an affected person. It is a genetic disorder inherited ...
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https://www.medgadget.com/2018/09/alpha-thalassemia-market-to-reflect-impressive-expansion-during-2018-2023-growing-at-gagr-of-8-8-asserts-mrfr-unleashing-market-insights-till-2023.html
Alpha thalassemia is a blood disorder that causes abnormal production of hemoglobin in an affected person. It is a genetic disorder inherited ...
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72
Hematological Parameter Evaluation in Different Types of ...
http://apps.amdi.usm.my/journal/index.php/jbcs/article/view/142
Alpha thalassemia is a common genetic disorder with more than 20% of the world population to be a carrier of some form of α–thalassemia, as estimated by The ...
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http://apps.amdi.usm.my/journal/index.php/jbcs/article/view/142
Alpha thalassemia is a common genetic disorder with more than 20% of the world population to be a carrier of some form of α–thalassemia, as estimated by The ...
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73
The Effect of α +-Thalassaemia on the Incidence of Malaria ...
https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030158
We studied the α+-thalassaemia-specific incidence of malaria and other common ... of the immune response to vaccination after acute malaria.
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https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030158
We studied the α+-thalassaemia-specific incidence of malaria and other common ... of the immune response to vaccination after acute malaria.
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74
Immunosuppression in Thalassemia - Robert Grady - Grantome
https://grantome.com/grant/NIH/R01-HL035533-02
We have been investigating the relationship between transfusional iron overload and immune function in patients with -thalassemia major.
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https://grantome.com/grant/NIH/R01-HL035533-02
We have been investigating the relationship between transfusional iron overload and immune function in patients with -thalassemia major.
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75
Blood Disorders | OSF Children's Hospital
https://www.osfhealthcare.org/childrens/services/cancer/conditions-we-treat/blood-disorders/
Alpha thalassemia – People whose hemoglobin does not produce enough alpha protein have alpha thalassemia. It is commonly found in Africa, the Middle East, India ...
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https://www.osfhealthcare.org/childrens/services/cancer/conditions-we-treat/blood-disorders/
Alpha thalassemia – People whose hemoglobin does not produce enough alpha protein have alpha thalassemia. It is commonly found in Africa, the Middle East, India ...
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76
What is Disease Tolerance? - AZoLifeSciences
https://www.azolifesciences.com/article/What-is-Disease-Tolerance.aspx
A study looking into the impact of alpha thalassemia, ... When a pathogen invades our body, it is the immune system's job to detect, target, ...
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https://www.azolifesciences.com/article/What-is-Disease-Tolerance.aspx
A study looking into the impact of alpha thalassemia, ... When a pathogen invades our body, it is the immune system's job to detect, target, ...
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77
A PROSPECTIVE STUDY OF THE INFLUENCE OF α ...
https://publications.aap.org/pediatrics/article/95/6/844/59358/A-PROSPECTIVE-STUDY-OF-THE-INFLUENCE-OF
... INFLUENCE OF α-THALASSAEMIA ON MORBIDITY FROM MARLARIA AND IMMUNE ... in vitro cellular immune response to specific malarial antigens.
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https://publications.aap.org/pediatrics/article/95/6/844/59358/A-PROSPECTIVE-STUDY-OF-THE-INFLUENCE-OF
... INFLUENCE OF α-THALASSAEMIA ON MORBIDITY FROM MARLARIA AND IMMUNE ... in vitro cellular immune response to specific malarial antigens.
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78
ATR-X Syndrome | Encyclopedia MDPI
https://encyclopedia.pub/6861
It's made up of alpha globin and beta globin. Normally each person has four genes for alpha globin, Alpha thalassemia happens when one or more of the genes that ...
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https://encyclopedia.pub/6861
It's made up of alpha globin and beta globin. Normally each person has four genes for alpha globin, Alpha thalassemia happens when one or more of the genes that ...
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79
Beta thalassemia and role of herbals and hematopoietic stem ...
https://medcraveonline.com/HTIJ/beta-thalassemia-and-role-of-herbals-and-hematopoietic-stem-cells-in-its-remedy.html
The intensiveness of β-thalassemia is associated with the extent of alpha and non-alpha globin chains imbalance. ... Its three main formsare β- ...
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https://medcraveonline.com/HTIJ/beta-thalassemia-and-role-of-herbals-and-hematopoietic-stem-cells-in-its-remedy.html
The intensiveness of β-thalassemia is associated with the extent of alpha and non-alpha globin chains imbalance. ... Its three main formsare β- ...
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80
Immune response and reactogenicity after ... - The Lancet
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00272-3/fulltext
The α error for statistical significance in primary analysis was corrected to 0·025 as per Bonferroni to adjust for multiple comparisons.
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https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00272-3/fulltext
The α error for statistical significance in primary analysis was corrected to 0·025 as per Bonferroni to adjust for multiple comparisons.
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81
The α-Thalassemias | NEJM
https://www.nejm.org/doi/10.1056/NEJMra1404415
These inherited disorders of hemoglobin synthesis are characterized by a reduced production of globin chains of hemoglobin. ... Worldwide, the ...
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https://www.nejm.org/doi/10.1056/NEJMra1404415
These inherited disorders of hemoglobin synthesis are characterized by a reduced production of globin chains of hemoglobin. ... Worldwide, the ...
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82
Heart & Blood Vessels - Connecticut Children's
https://www.connecticutchildrens.org/health-library/for-parents/medical/heart/
Alpha thalassemia is a blood disorder in which the body has a problem producing alpha globin, a component of hemoglobin, the protein in red blood cells that ...
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https://www.connecticutchildrens.org/health-library/for-parents/medical/heart/
Alpha thalassemia is a blood disorder in which the body has a problem producing alpha globin, a component of hemoglobin, the protein in red blood cells that ...
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83
Human Gene HBB (ENST00000647020.1) from GENCODE V41
https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_chrom=chr11&hgg_gene=ENST00000647020.1&hgg_start=5225464&hgg_end=5227071&hgg_type=knownGene
In the severe forms of beta-thalassemia, the excess alpha globin chains accumulate in the developing erythroid precursors in the marrow. Their deposition leads ...
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https://genome.ucsc.edu/cgi-bin/hgGene?db=hg38&hgg_chrom=chr11&hgg_gene=ENST00000647020.1&hgg_start=5225464&hgg_end=5227071&hgg_type=knownGene
In the severe forms of beta-thalassemia, the excess alpha globin chains accumulate in the developing erythroid precursors in the marrow. Their deposition leads ...
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84
Sickle cell disease and thalassaemia - NaTHNaC
https://travelhealthpro.org.uk/factsheet/98/sickle-cell-disease-and-thalassaemia
Both alpha and beta thalassaemia are classified further according to ... Current advice is that anyone with a weakened immune system is at ...
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https://travelhealthpro.org.uk/factsheet/98/sickle-cell-disease-and-thalassaemia
Both alpha and beta thalassaemia are classified further according to ... Current advice is that anyone with a weakened immune system is at ...
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85
Estimating the burden of α-thalassaemia in Thailand using a ...
https://elifesciences.org/articles/40580
Severe forms of α-thalassaemia, haemoglobin H disease and haemoglobin Bart's hydrops fetalis, are an important public health concern in ...
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https://elifesciences.org/articles/40580
Severe forms of α-thalassaemia, haemoglobin H disease and haemoglobin Bart's hydrops fetalis, are an important public health concern in ...
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86
Inherited Disorders of Hemoglobin and Plasmodium ...
https://www.intechopen.com/chapters/73837
Some studies [90, 102, 103, 104] investigated α-thalassaemia showed protection against severe malaria, malarial anemia and additionally, protection from ...
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https://www.intechopen.com/chapters/73837
Some studies [90, 102, 103, 104] investigated α-thalassaemia showed protection against severe malaria, malarial anemia and additionally, protection from ...
→ Check Latest Keyword Rankings ←
87
Myocarditis in β-Thalassemia Major | Circulation - AHA Journals
https://www.ahajournals.org/doi/full/10.1161/01.cir.91.1.66
Infectious myocarditis, possibly related to a high prevalence of infections due to abnormalities of the immune system, can cause acute or chronic left ...
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https://www.ahajournals.org/doi/full/10.1161/01.cir.91.1.66
Infectious myocarditis, possibly related to a high prevalence of infections due to abnormalities of the immune system, can cause acute or chronic left ...
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88
Anemia:- Part 4 - Thalassemia, α-thalassemia and β ...
https://labpedia.net/anemia-part-4-thalassemia-alpha-thalassemia-beta-thalassemia-discussion-and-workup/
α-thalassemia is a group of genetic disorders with defective α-chain synthesis. Chromosome 16 carries 2 α genes, and the total number of α-gene ...
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https://labpedia.net/anemia-part-4-thalassemia-alpha-thalassemia-beta-thalassemia-discussion-and-workup/
α-thalassemia is a group of genetic disorders with defective α-chain synthesis. Chromosome 16 carries 2 α genes, and the total number of α-gene ...
→ Check Latest Keyword Rankings ←
89
Comprehensive hemoglobinopathy programs
https://pediatrics.northwell.edu/departments-services/pediatric-hematology-oncology/programs-services/comprehensive-hemoglobinopathy-programs
There are two main types of thalassemia, beta thalassemia and alpha thalassemia. The most severe type of thalassemia is beta thalassemia major. Children with ...
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https://pediatrics.northwell.edu/departments-services/pediatric-hematology-oncology/programs-services/comprehensive-hemoglobinopathy-programs
There are two main types of thalassemia, beta thalassemia and alpha thalassemia. The most severe type of thalassemia is beta thalassemia major. Children with ...
→ Check Latest Keyword Rankings ←
90
Pregnancy in women with thalassemia - Dove Medical Press
https://www.dovepress.com/pregnancy-in-women-with-thalassemia-challenges-and-solutions-peer-reviewed-fulltext-article-IJWH
The α-globin chain synthesis begins in fetal life. The responsible genes – four in total – are situated in two genetic loci in chromosome 16.
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https://www.dovepress.com/pregnancy-in-women-with-thalassemia-challenges-and-solutions-peer-reviewed-fulltext-article-IJWH
The α-globin chain synthesis begins in fetal life. The responsible genes – four in total – are situated in two genetic loci in chromosome 16.
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91
Screened Disorders
https://www.dshs.texas.gov/newborn/screened_disorders.aspx
Sickle Beta Zero Thalassemia (Hb S/Th) is a condition in which the ... The body's immune system is made up of different parts that work ...
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https://www.dshs.texas.gov/newborn/screened_disorders.aspx
Sickle Beta Zero Thalassemia (Hb S/Th) is a condition in which the ... The body's immune system is made up of different parts that work ...
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92
Beta thalassaemia notes - Pulsenotes | Library
https://app.pulsenotes.com/medicine/haematology/notes/beta-thalassaemia
Alpha thalassaemia: reduced or absent production of the alpha globin ... which refers to development of an immune response to red blood cell antigens.
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https://app.pulsenotes.com/medicine/haematology/notes/beta-thalassaemia
Alpha thalassaemia: reduced or absent production of the alpha globin ... which refers to development of an immune response to red blood cell antigens.
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93
Retrospective analysis of thalassemia patients in secondary ...
https://www.advbiores.net/article.asp?issn=2277-9175;year=2022;volume=11;issue=1;spage=53;epage=53;aulast=Assadi
In alpha-thalassemia (α-thalassemia), there is a decrease in the making of α-globin chains, and this results in a reduced red cell (erythrocyte) ...
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https://www.advbiores.net/article.asp?issn=2277-9175;year=2022;volume=11;issue=1;spage=53;epage=53;aulast=Assadi
In alpha-thalassemia (α-thalassemia), there is a decrease in the making of α-globin chains, and this results in a reduced red cell (erythrocyte) ...
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94
Identification of four common α-thalassemia gene deletions ...
https://www.degruyter.com/document/doi/10.1515/pterid-2013-0034/html
α-Thalassemia (α-thal) is one of the most common genetic disorders in the world. It is characterized by the absence or reduced expression of ...
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https://www.degruyter.com/document/doi/10.1515/pterid-2013-0034/html
α-Thalassemia (α-thal) is one of the most common genetic disorders in the world. It is characterized by the absence or reduced expression of ...
→ Check Latest Keyword Rankings ←
95
Biochemical and Hematological Study with the Appreciation of ...
https://microbiologyjournal.org/biochemical-and-hematological-study-with-the-appreciation-of-some-immunological-parameters-in-thalassemia-patients-at-kerbala-province/
Seventy patients involved 48 beta thalassemia patients and 22 alpha thalassemia ... There are many disorders in the immune system of b-thalassemia patients ...
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https://microbiologyjournal.org/biochemical-and-hematological-study-with-the-appreciation-of-some-immunological-parameters-in-thalassemia-patients-at-kerbala-province/
Seventy patients involved 48 beta thalassemia patients and 22 alpha thalassemia ... There are many disorders in the immune system of b-thalassemia patients ...
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96
Cardiac aspects of ß-Thalassemia
https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-5/Cardiac-aspects-of-Thalassemia-Title-Cardiac-aspects-of-Thalassemia
Myocardial iron overload is a common finding in ß-thalassemia. ... high incidences of infections due to abnormalities of the immune system.
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https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-5/Cardiac-aspects-of-Thalassemia-Title-Cardiac-aspects-of-Thalassemia
Myocardial iron overload is a common finding in ß-thalassemia. ... high incidences of infections due to abnormalities of the immune system.
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97
Baby born in world's first in utero stem cell transplant trial
https://www.universityofcalifornia.edu/news/baby-born-worlds-first-utero-stem-cell-transplant-trial
The trial is looking to treat alpha thalassemia, a fetal anemia ... With current advances in the understanding of the fetal immune system, ...
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https://www.universityofcalifornia.edu/news/baby-born-worlds-first-utero-stem-cell-transplant-trial
The trial is looking to treat alpha thalassemia, a fetal anemia ... With current advances in the understanding of the fetal immune system, ...
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