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1 How to build a genome - Nature
https://www.nature.com/articles/d41586-020-00511-9
› technology features
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2 Build A Genome Network - QUBES Hub
https://qubeshub.org/community/groups/bag
Build-a-Genome (BAG). BAG is a course-based undergraduate research experience in which students create synthetic genomes. Pioneered at Johns Hopkins ...
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3 The build-a-genome course - Johns Hopkins University
https://jhu.pure.elsevier.com/en/publications/the-build-a-genome-course-3
Build-a-Genome is an intensive laboratory course at Johns Hopkins University that introduces undergraduates to the burgeoning field of synthetic biology.
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4 How to Build a Genome | Center for Genetics and Society
https://www.geneticsandsociety.org/article/how-build-genome
› article › how-buil...
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5 Build-a-Genome - Johns Hopkins Engineering Online
https://ep.jhu.edu/courses/580420-build-a-genome/
Build-a-Genome. View All Course Homepages for this course. Play background animation. Pause background animation. Course Number. 580.420 ...
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6 Award # 1827204 - RCN-UBE: The Build-a-Genome Network
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1827204
The Build-a-Genome Network will develop and support diverse synthetic biology workflows that can be implemented at the undergraduate level including the ...
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7 Genome build information is an essential part of genomic track ...
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1312-1
Therefore, for files that exclusively provide data in the form of coordinates on a reference genome, such as BED, WIG or GFF, the genome build ...
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8 Introduction to Genome Builds and Transcripts - YouTube
https://www.youtube.com/watch?v=pg6IjH4Oits
ClinGen Resource
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9 Scientists reveal proposal to build human genome from scratch
https://www.science.org/content/article/scientists-reveal-proposal-build-human-genome-scratch
Last year, researchers working to synthesize the genome of a strain of yeast began to eye a much bigger prize: assembling from scratch the 3 billion base ...
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10 Do You Want to Build a Genome? Benchmarking Hybrid ...
https://www.biorxiv.org/content/10.1101/2021.11.07.467652v1
Long read sequencing technologies now allow routine highly contiguous assembly of bacterial genomes. However, because of the lower accuracy ...
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11 The Build-a-Genome Course | Springer Nature Experiments
https://experiments.springernature.com/articles/10.1007/978-1-61779-564-0_20
Build-a-Genome is an intensive laboratory course at Johns Hopkins University that introduces undergraduates to the burgeoning field of synthetic biology.
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12 Human genome reference builds - GRCh38 or hg38 - b37
https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19
In a perfect world, the human reference genome should represent all of humanity faithfully. In practice, this is rather difficult to achieve due to the great ...
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13 The Build-a-Genome Course | SpringerLink
https://link.springer.com/protocol/10.1007/978-1-61779-564-0_20
Build-a-Genome is an intensive laboratory course at Johns Hopkins University that introduces undergraduates to the burgeoning field of ...
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14 How to read the genome and build a human being - YouTube
https://www.youtube.com/watch?v=s6rJLXq1Re0
May 24, 2016
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15 Building a Synthetic Eukaryotic Genome - GenScript
https://www.genscript.com/building-synthetic-eukaryotic-genome.html
First, to improve genomic stability, destabilizing elements such as transposons are removed and tRNA genes are re-located to a separate 'neochromosome'. Second, ...
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16 GIVE: Build your own genome browser - GitHub Pages
https://zhong-lab-ucsd.github.io/GIVE_homepage/
GIVE is an open source programming library that allows anyone without much programming experience to build custom genome browser websites or apps.
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17 Twelve quick steps for genome assembly and annotation in ...
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008325
To sequence an organism's entire genome (WGS), it must be prepared into a sample library from high-quality genomic DNA. A library is a ...
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18 Reference genome - Wikipedia
https://en.wikipedia.org/wiki/Reference_genome
A reference genome is a digital nucleic acid sequence database, assembled by scientists as a representative example of the set of genes in one idealized ...
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19 Invitation to Build-a-Genome network virtual workshop
https://serc.carleton.edu/curenet/news/238350.html
Apply for the third national Build-a-Genome (BAG) workshop! Build-a-Genome was developed by Dr. Jef Boeke as part of the International and ...
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20 Building a custom high-throughput platform at the Joint ...
https://academic.oup.com/synbio/article/5/1/ysaa023/5956843
Building a custom high-throughput platform at the Joint Genome Institute for DNA construct design and assembly—present and future challenges.
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21 From DNA to FBA: How to Build Your Own Genome-Scale ...
https://www.frontiersin.org/articles/10.3389/fmicb.2016.00907/full
A mathematical model consisting of a microbe's entire metabolic map can be rapidly determined from whole-genome sequencing and annotating the ...
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22 Synthetic Biology: Minimal cells, maximal knowledge - eLife
https://elifesciences.org/articles/45379
By building and studying these very simplified cells – so simple they ... creating a genome from scratch in a laboratory demonstrated the ...
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23 Custom Genomes - Galaxy Community Hub
https://galaxyproject.org/learn/custom-genomes/
Custom Builds · Start with an existing fasta Custom Reference Genome in your history. · Go to the top "User" menu and select "Custom Builds" · Enter in the labels ...
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24 Creating Genome Groups - PATRIC Documentation
https://docs.patricbrc.org/tutorial/genome_groups/creating_genome_groups.html
Clicking on the box in front of Genome Name will select all of the genomes (Red Arrow), or they can be selected individually. Once a genome is selected, the ...
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25 Build-a-Genome Tickets, Sat, Oct 1, 2022 at 9:00 AM | Eventbrite
https://www.eventbrite.com/e/build-a-genome-tickets-426492298947
Eventbrite - Baltimore Under Ground Science Space presents Build-a-Genome - Saturday, October 1, 2022 at Baltimore Under Ground Science ...
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26 A Brief Guide to Genomics
https://www.genome.gov/about-genomics/fact-sheets/A-Brief-Guide-to-Genomics
Genome-based research is already enabling medical researchers to develop improved diagnostics, more effective therapeutic strategies, evidence- ...
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27 Writing-human-genome - C&EN - American Chemical Society
https://cen.acs.org/articles/95/i28/Writing-human-genome.html
Synthetic biologists have been creating the genomes of organisms such as viruses and bacteria for the past 15 years.
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28 10 reasons to build the human genome from scratch - Medium
https://medium.com/@andrewhessel/10-reasons-to-build-the-human-genome-from-scratch-61df68be4a02
The Human Genome Project launched in 1990 with the goal to read genomes. Now scientists are working to write them. The Genome Project-write ...
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29 Build a Custom Reference (cellranger mkref) -Software - Support
https://support.10xgenomics.com/single-cell-gene-expression/software/pipelines/latest/using/tutorial_mr
10x Genomics provides pre-built references for human and mouse genomes to use with Cell Ranger. Researchers can make custom reference genomes for additional ...
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30 Building a new genome database - genomewiki
http://genomewiki.ucsc.edu/index.php/Building_a_new_genome_database
Building a new genome database · 1. Organize your work. · 2. You should have fasta file(s) of your genome sequence and an AGP file describing ...
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31 Inside the effort to create entire genomes from scratch
https://massivesci.com/articles/its-alive-yeast-genome-create-life/
The idea is that building genomes from scratch will answer fundamental questions about why our genomes look the way they do, and eventually, ...
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32 Why are scientists building a synthetic yeast genome? - ABC
https://www.abc.net.au/news/science/2019-09-28/synthetic-yeast-genome/11534242
Every one of us, and indeed every living thing, has our own natural genome. It's encoded by DNA and makes us what we are — it's our complete set ...
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33 Teaching Synthetic Biology, Bioinformatics and Engineering to ...
https://www.researchgate.net/publication/23479793_Teaching_Synthetic_Biology_Bioinformatics_and_Engineering_to_Undergraduates_The_Interdisciplinary_Build-a-Genome_Course
We are pursuing synthesis of Saccharomyces cerevisiae chromosomes in an undergraduate laboratory setting, the Build-a-Genome course, thereby ...
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34 Creating a genome group - Protein Family Sorter | Coursera
https://www.coursera.org/lecture/informatics/creating-a-genome-group-gyHh7
Creating a genome group ... This course provides demonstrations and exercises for performing common genomics-based analysis tasks of bacterial ...
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35 Building Synthetic Genomes: Life from Scratch? - NPR
https://www.npr.org/templates/story/story.php?storyId=18417061
Scientists in the lab of genome pioneer Craig Venter have built an artificial copy of a bacterium's genome. The new work, reported in the ...
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36 Scientists Created Bacteria With a Synthetic Genome. Is This ...
https://www.nytimes.com/2019/05/15/science/synthetic-genome-bacteria.html
The Cambridge team is just one of many racing in recent years to build synthetic genomes. The list of potential uses is a long one. One ...
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37 Why would scientists want to build human genomes from ...
https://www.newscientist.com/article/2088703-why-would-scientists-want-to-build-human-genomes-from-scratch/
Synthetic bacterial genomes have already been created, but the human genome is thousands of times larger, making it much harder to synthesise.
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38 Salk Research Professor Todd Michael receives $2 million to ...
https://www.salk.edu/news-release/salk-research-professor-todd-michael-receives-2-million-to-build-a-genome-repository-for-the-cassava-plant/
His team, which includes scientists from Cornell University, will then develop software to visualize all the cassava genomes together in ...
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39 These Scientists Want To Build A Human Genome From Scratch
https://www.buzzfeednews.com/article/nidhisubbaraman/synthetic-human-genome
With this lofty pitch for the “Human Genome Project-Write,” the group hopes to attract major funders and collaborators to synthesize the human ...
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40 Designer Yeast: Building the First Synthetic Eukaryotic Genome
https://med.nyu.edu/research/boeke-lab/research/designer-yeast
0. As a proof of concept, the project was initially fueled by an army of undergraduates at Johns Hopkins University in the "Build A Genome" course where ...
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41 Mapping reads to a reference genome - Homer
http://homer.ucsd.edu/homer/basicTutorial/mapping.html
Step 1 - Build Index (takes a while, but only do this once): ... After installing bowtie2, the reference genome must first be "indexed" so that reads may be ...
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42 New DNA Synthesis Method Could Soon ... - Singularity Hub
https://singularityhub.com/2018/07/10/new-dna-synthesis-method-could-soon-build-a-genome-in-a-day/
New DNA Synthesis Method Could Soon Build a Genome in a Day ... Synthetic biologists are the computer programmers of biology. Their code? DNA. The ...
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43 Alternative transcriptome analysis to build the genome ...
https://www.sciencedirect.com/science/article/pii/B9780128205952000047
In principle, the expression of a large number of alternative transcripts enables a finite genome to build an infinite phenome because almost every gene ...
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44 This CAD Program Can Design New Organisms
https://spectrum.ieee.org/genome-editing-cad
Those fragments of synthesized DNA can then be sent to a foundry for assembly, and finally to a lab where the designed genomes can be tested in cells. Based on ...
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45 Whole-Genome Synthesis Will Transform Cell Engineering
https://www.scientificamerican.com/article/whole-genome-synthesis-will-transform-cell-engineering/
Whole-genome synthesis is an extension of the booming field of synthetic biology. Researchers use software to design genetic sequences that they ...
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46 A Building Block for a Model Organism System Database
https://genome.cshlp.org/content/12/10/1599.full.html
It is important to note that with respect to genomic data, the key role of the model organism databases is to connect genomic features to the classical biology ...
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47 Genome Project-write - Wiki | Golden
https://golden.com/wiki/Genome_Project-write-PJ64BA
Synthetic genome recoding is the process of changing the three-letter DNA sequences called codons which encode amino acids, building blocks of proteins. This is ...
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48 Genome Mapping - Learn Genetics Utah
https://learn.genetics.utah.edu/content/cotton/genome
A genome contains all of the instructions for building and operating an organism. Having a genome map helps us do things like diagnose and treat diseases, ...
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49 Tophat2 : Download, build reference genome and align the ...
http://www.sthda.com/english/wiki/tophat2-download-build-reference-genome-and-align-the-reads-to-the-reference-genome
Assess sequence quality control with ShortRead · Prepare your sample metadata informations · Align the reads to reference genome using tophat2 · Use R to create ...
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50 GitHub - buds-lab/the-building-data-genome-project
https://github.com/buds-lab/the-building-data-genome-project
Introducing the Building Data Genome Project ... It is an open data set from 507 non-residential buildings that includes hourly whole building electrical meter ...
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51 New computer software to advance genome design capabilities
https://www.eurekalert.org/news-releases/666446
"The CAD technology provides an important tool to make genome engineering and biological discovery more accessible to a wider spectrum of ...
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52 Scientists plan to build human genome from scratch « Kurzweil
https://www.kurzweilai.net/scientists-plan-to-build-human-genome-from-scratch
Leading genomics experts have announced Genome Project-write (HGP-write), which aims to synthesize entire genomes of humans and other species ...
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53 Scientists Create E. Coli Bacteria With Completely Synthetic ...
https://www.smithsonianmag.com/smart-news/scientists-create-e-coli-bacteria-completely-synthetic-genome-180972214/
To “recode” a genome, scientists must manipulate the 64 codons, or three-letter combinations of the DNA molecules A, T, C and G—short for ...
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54 Scientists Create Artificial Genome That Can Reproduce
https://futurism.com/the-byte/scientists-create-artificial-genome-reproduce
› the-byte › scientists-create-artifici...
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55 How Synthetic Biology Will Help Me Live Forever | WIRED
https://www.wired.com/story/live-forever-synthetic-human-genome/
Researchers want to synthesize an optimized human genome that can be stored ... His plan is to design and build long chains of human DNA, ...
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56 Build a genome - Synthetic Yeast 2.0
http://syntheticyeast.org/build-a-genome/
› build-a-genome
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57 The Genome Foundry ushers Canada into the era of ...
https://www.universityaffairs.ca/news/news-article/the-genome-foundry-ushers-canada-into-the-era-of-automated-genetic-engineering/
The development opens the door to understanding and building entire genomes, comprised of tens of thousands of genes, faster than ever ...
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58 Why are scientists building a synthetic yeast genome?
https://research.csiro.au/synthetic-biology-fsp/why-are-scientists-building-a-synthetic-yeast-genome/
On the other hand, a synthetic genome is one that scientists have completely redesigned on a computer. Then they can chemically synthesised the ...
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59 Synthetic Genomes | Annual Review of Biochemistry
https://www.annualreviews.org/doi/abs/10.1146/annurev-biochem-013118-110704
The techniques and technologies relating to how to design, build, and deliver big DNA at the genome scale are reviewed here. A fuller understanding of these ...
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60 150 Scientists Just Met in Secret to Discuss Creating a ...
https://www.sciencealert.com/150-scientists-just-met-in-secret-to-discuss-creating-a-synthetic-human-genome
The project, called HGP-Write: Testing Large Synthetic Genomes in Cells, aims to "synthesise a complete human genome in a cell line within a ...
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61 buildindex: Build Index for a Reference Genome in Rsubread
https://rdrr.io/bioc/Rsubread/man/buildindex.html
To build a full index for human/mouse genome, buildindex function requires 15GB memory. When using a full index to map reads to human/mouse genome, align and ...
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62 Scientists create 'designer yeast' in major step toward ...
https://www.washingtonpost.com/news/speaking-of-science/wp/2017/03/09/scientists-create-designer-yeast-in-major-step-toward-synthetic-life/
Craig Venter Institute created a bacterial cell controlled by a synthesized genome by copying the DNA of one bacterium into another. Last year ...
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63 DNA Synthesis Science Program - DOE Joint Genome Institute
https://jgi.doe.gov/our-science/science-programs/synthetic-biology/
The JGI has developed a suite of build-optimization software tools (BOOST) to streamline the design-build transition in synthetic biology engineering workflows.
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64 Illumina | Sequencing and array-based solutions for genetic ...
https://www.illumina.com/
Illumina sequencing and array technologies fuel advancements in life science research, translational and consumer genomics, and molecular diagnostics.
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65 Reading the Neandertal Genome Build Your Own ... - Hu Li Lab
http://hulilab.org/files/science_runnersup.pdf
› files › science_runnersup
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66 How do you map a genome? - YourGenome
https://www.yourgenome.org/facts/how-do-you-map-a-genome/
Genome mapping is used to identify and record the location of genes and ... are passed on was applied to develop the first human genome map.
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67 Scientists Discuss Building Synthetic Genome - Business Insider
https://www.businessinsider.com/scientists-discuss-building-synthetic-genome-2016-5
Synthesizing genomes involves building them from the ground up — chemically combining molecules to create DNA. Similar work by Craig Venter in ...
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68 STAR manual 2.7.0a
https://physiology.med.cornell.edu/faculty/skrabanek/lab/angsd/lecture_notes/STARmanual.pdf
3.3 Using shared memory for the genome indexes. ... To compile STAR from sources run make in the source directory for a Linux-like ...
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69 Genome Code Builds the Case for Creation
https://reasons.org/explore/blogs/the-cells-design/genome-code-builds-the-case-for-creation
Chromosomes. DNA and proteins interact to make chromosomes. · The Genome Code · Genomic Code Challenges the Junk DNA Concept · The ENCODE Project.
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70 Building a genome engineering toolbox in nonmodel ...
https://onlinelibrary.wiley.com/doi/10.1002/bit.26727
In a bioengineering context, evolutionary methods include the creation of genome-scale libraries of mutations or strains overexpressing genomic ...
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71 How Do Scientists Assemble A Genome? - UC Davis
https://www.ucdavis.edu/curiosity-gap/how-do-scientists-assemble-genome
A genome contains all the genetic information needed to create and maintain an individual. Sequencing a genome helps scientists better ...
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72 10 reasons to build the human genome from scratch
https://churchandstate.org.uk/2019/11/10-reasons-to-build-the-human-genome-from-scratch/
Being able to write the complete genome of a cell will make it easier to program and optimize these factories for high-efficiency ...
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73 Genome engineering: writing a better genome | BioTechniques
https://www.future-science.com/doi/10.2144/000113934
The practical portion of the course involves reconstructing a yeast chromosome, base by base, from chemical building blocks. It's part of a ...
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74 Souped up genome makes bacteria impervious to viral attack
https://www.statnews.com/2021/06/03/with-souped-up-synthetic-genome-scientists-make-bacteria-impervious-to-viral-attack/
coli's genome, creating a bacteria, dubbed Syn61, that lived and squirmed and formed colonies despite using 61 codons rather than nature's 64.
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75 World's first living organism with fully redesigned DNA created
https://www.theguardian.com/science/2019/may/15/cambridge-scientists-create-worlds-first-living-organism-with-fully-redesigned-dna
Researchers create altered synthetic genome, in move with potential medical benefits.
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76 First Replicating Cell Driven by Synthetic Genome Created by ...
https://www.genengnews.com/topics/genome-editing/first-replicating-cell-driven-by-synthetic-genome-created-by-venter-institute/
“The DNA software builds its own hardware,” the researchers write in the published Science paper, titled, “Creation of a Bacterial Cell ...
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77 The Sc2.0 UK Genome Engineering Resource (SUGER)
https://www.eng.ed.ac.uk/research/projects/sc20-uk-genome-engineering-resource-suger
While synthetic biology has many facets, a sub-discipline termed “synthetic genomics” seeks to build genomes of various types. The Craig Venter ...
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78 New DNA Synthesis Method Could Soon Build a Genome in a ...
https://chemistry.berkeley.edu/news/new-dna-synthesis-method-could-soon-build-genome-day
New DNA Synthesis Method Could Soon Build a Genome in a Day. July 10, 2018. Shelly Fan. DNA strand A new method from the lab of Jay Keasling promises to ...
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79 Researchers Develop Algorithm, Assay to Assess Genome ...
https://healthitanalytics.com/news/researchers-develop-algorithm-assay-to-assess-genome-structure
New technology allows researchers to analyze the three-dimensional structure of the human genome, which may help shed light on the ...
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80 Scientists create first 3-D map of human genome - Phys.org
https://phys.org/news/2012-01-scientists-d-human-genome.html
The technique adds a crucial piece of the puzzle for scientists trying to understand the genome — the cornerstone of life — in normal and ...
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81 "Digital Genome Engineering: Unlocking the Potential of ...
https://www.inscripta.com/blog/digital-genome-engineering-unlocking-the-potential-of-synthetic-biology-symposium-highlights
This did not stop us, however, as we decided to partner with Build With Biology to put on a half-day virtual symposium “Digital Genome ...
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82 Genotyping chip data lift-over to reference genome build ...
https://www.protocols.io/view/genotyping-chip-data-reference-genome-build-lift-o-nqtddwn
Genotyping chip data lift-over to reference genome build GRCh38/hg38 V.1. DOI. dx.doi.org/10.17504/protocols.io.nqtddwn.
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83 Scientists propose project to build synthetic human genome
https://www.reuters.com/article/science-genome/scientists-propose-project-to-build-synthetic-human-genome-idINL1N18U1LU
The project, which arose from a meeting of scientists last month at Harvard University, aims to build such a synthetic genome and test it in ...
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84 Hopkins undergraduates build novel genome
https://www.jhunewsletter.com/article/2014/04/hopkins-undergraduates-build-novel-genome-67229
With the help of Hopkins undergraduate students in the “Build-A-Genome” class, scientists have created the world's first synthetic yeast ...
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85 International Tomato Genome Sequencing Project
https://solgenomics.net/organism/Solanum_lycopersicum/genome
The International Tomato Annotation Group (ITAG) annotates the genome builds generated by this combined sequencing approach.
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86 GenomeTools
http://genometools.org/
The GenomeTools genome analysis system is a free collection of bioinformatics tools (in the realm of genome informatics) combined into a single binary.
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87 Should Scientists Create a Synthetic Human Genome?
https://www.thehastingscenter.org/news-in-context/should-scientists-create-a-synthetic-human-genome/
On June 2, a group of leading scientists announced their intention to build an entire human genome from scratch. While the fabricated genome ...
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88 Swiss Synthetic Biologists Make Bacterial Genome Using ...
https://www.labiotech.eu/more-news/synthetic-biology-eth-zurich/
Synthetic biology researchers at ETH Zurich are the first to construct a simplified artificial bacterial genome with the help of computer ...
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89 Setting up a genome for analysis — plastid documentation
https://plastid.readthedocs.io/en/latest/examples/a1_genome_setup.html
Obtain a genome sequence & matching annotation. Choose a curator. Download files ; Convert file formats. Extract genome sequence from GFF3. Make an indexed ...
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90 Early Access to 'Build 38' for Improved Clinical Genome Analysis
https://fabricgenomics.com/early-access-to-build-38/
It repairs incorrect assemblies from Build 37, removes some incorrectly assigned pathogenic alleles, adds centromere sequences and improves the reference genome ...
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91 Creating and Using Genome Assemblies in SVS Tutorial
https://www.goldenhelix.com/learning/knowledge-base/creating-and-using-genome-assemblies-in-svs-tutorial/
To create a genome assembly for any species you need a listing of the assembled chromosomes and/or scaffolds along with their corresponding lengths for the ...
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92 build Genome version
https://support.bioconductor.org/p/38146/
Hi, I want to known that is the build genome version used in affymetrix CDF packages (e.g. : hgu133plu2cdf). I guess in bioconductor 2.7, the gemome build ...
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93 Reference genome: defining human difference
https://www.genomicseducation.hee.nhs.uk/blog/reference-genome-defining-human-difference/
The current human reference genome build, known as GRCh38, is used worldwide, but whose genome is it based on and how reliable is it?
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94 The Human Genome Project—discovering the human blueprint
https://www.science.org.au/curious/people-medicine/human-genome-project
The human genome is the complete set of instructions required to create a human being. Our DNA what makes us all human – yet different.
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95 Manual - Bowtie 2
https://bowtie-bio.sourceforge.net/bowtie2/manual.shtml
When the genome is longer, bowtie2-build builds a "large" index using 64-bit numbers. Small indexes are stored in files with the .bt2 extension, and large ...
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96 MGI-Mouse Genome Informatics-The international database ...
http://www.informatics.jax.org/
... integrated genetic, genomic, and biological data for researching human health and disease. ... MGI is updated to the reference genome Build 39.
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