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1 Genetics, Philadelphia Chromosome - StatPearls - NCBI - NIH
https://www.ncbi.nlm.nih.gov/books/NBK560689/
Philadelphia chromosome is detectable with cytogenetic testing, or a reverse transcriptase PCR test can demonstrate the BCR/ABL transcripts.
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2 BCR-ABL1 Test - Testing.com
https://www.testing.com/tests/bcr-abl1/
This test looks at chromosomes under a microscope to detect structural and/or numerical abnormalities. For example, the Philadelphia chromosome ...
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3 BCR-ABL1 (BCR::ABL1) Qualitative and Quantitative Testing
https://arupconsult.com/ati/bcr-abl1-qualitative-and-quantitative-testing
Supplementary test information for BCR-ABL1 (BCR::ABL1) Qualitative and ... residual disease (MRD) assessment of Philadelphia chromosome positive (Ph+) ALL.
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4 Definition of Philadelphia chromosome - NCI
https://www.cancer.gov/publications/dictionaries/cancer-terms/def/philadelphia-chromosome
An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often ...
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5 Test Details - BCR-ABL RNA PCR Quantitation for Leukemia
https://knightdxlabs.ohsu.edu/home/test-details?id=BCR-ABL+RNA+PCR+Quantitation+for+Leukemia
The quantitative BCR-ABL RNA assay is intended to monitor the level of minimal residual disease in TKI-treated Philadelphia chromosome positive leukemias (CML ...
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6 Quantitative Analysis for BCR-ABL Fusion Transcripts
https://www.uhhospitals.org/for-clinicians/specialties/pathology/genomic-and-molecular-pathology/tests-offered/quantitative-analysis-for-bcr-abl-fusion-transcripts
Philadelphia chromosome was found in about 90 to 95 percent of chronic myeloid leukemia (CML) cases. This translocation also has been found in 25 to 30 percent ...
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7 BCR-ABL1 - Pathology Tests Explained
https://pathologytestsexplained.org.au/learning/test-index/em-bcr-abl1-em
Testing for BCR-ABL1 detects the Philadelphia chromosome, the BCR-ABL1 fusion gene, or BCR-ABL1 transcripts, which are the RNA copies made ...
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8 How the Philadelphia chromosome forms - Mayo Clinic
https://www.mayoclinic.org/diseases-conditions/chronic-myelogenous-leukemia/multimedia/how-the-philadelphia-chromosome-forms/img-20007421
An abnormal chromosome called the Philadelphia chromosome is associated with chronic myelogenous leukemia. Your cells each contain 23 pairs of chromosomes ...
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9 PHLDF - Overview: Philadelphia Chromosome-like Acute ...
https://www.mayocliniclabs.com/test-catalog/overview/609577
This test includes a charge for the probe application, analysis, and professional interpretation of results for 7 probe sets (14 individual fluorescence in ...
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10 Philadelphia Chromosome - an overview | ScienceDirect Topics
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/philadelphia-chromosome
The Philadelphia chromosome or Philadelphia translocation is a specific chromosomal abnormality that is associated with chronic myelogenous leukemia (CML).
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11 t(9;22)/Philadelphia Chromosome | Poplar Health Care
https://poplarhealthcare.com/testdirectory/tests/t922philadelphia-chromosome/
Test Name: t(9;22)/Philadelphia Chromosome · Methodology: FISH · Turn Around Time (TAT): 1-3 Days · CPT Codes*: 88368x1, 88369x2 ...
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12 Testing for gene changes in chronic myeloid leukaemia (CML)
https://www.cancerresearchuk.org/about-cancer/chronic-myeloid-leukaemia-cml/getting-diagnosed/tests/genetic-tests
Doctors can see the Philadelphia chromosome when they look at blood and bone marrow under the microscope. So they use it to help diagnose CML and to monitor ...
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13 Philadelphia chromosome-positive chronic myeloid leukemia
https://www.medicalnewstoday.com/articles/philadelphia-chromosome-positive-chronic-myeloid-leukemia
Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) causes abnormal changes to the chromosomes that lead to high levels of ...
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14 Bcr/abl - Quantitative (philadelphia Chromosome) test online ...
https://www.srlworld.com/test/agra/100001659/bcr-abl-quantitative-philadelphia-chromosome
A BCR-ABL genetic test looks for a genetic mutation (change) on a specific chromosome. BCR-ABL is a mutation that is formed by the combination of two genes, ...
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15 Treatment and monitoring of Philadelphia chromosome ...
https://jhoonline.biomedcentral.com/articles/10.1186/s13045-019-0729-2
In both CML and Ph-positive (Ph+) ALL, tyrosine kinase inhibitors (TKIs) have significantly improved outcomes. In the TKI era, testing for ...
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16 Molecular Genetic Testing For BCR-ABL1 Fusion Gene
https://www.cincinnatichildrens.org/-/media/cincinnati%20childrens/home/service/d/diagnostic-labs/molecular-genetics/test-disorder/bcr-abl%20quant%20test%20information.pdf?la=en
BCR-ABL1 test can determine the specific type (isoform) of the Philadelphia chromosome present which is important for appropriate diagnosis and treatment.
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17 How I diagnose and manage Philadelphia chromosome-like ...
https://www.haematologica.org/article/view/9116
One screening approach is to search for a specific phenotype using limited sets of genes.34 Alternatively, a panel of FISH probes or polymerase ...
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18 FISH, CML/ALL, bcr/abl, Translocation 9,22 | Test Detail
https://testdirectory.questdiagnostics.com/test/test-detail/12070/fish-cmlall-bcrabl-translocation-922?p=r&cc=MASTER
FISH, CML/ALL, bcr/abl, Translocation 9,22 - This test uses fluorescence in situ hybridization (FISH) to detect molecular rearrangement of the BCR and ABL1 ...
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19 150500: Chronic Myelogenous Leukemia (CML) Profile
https://www.labcorp.com/tests/150500/chronic-myelogenous-leukemia-cml-profile-chromosome-analysis-and-i-bcr-abl-i-fish
Labcorp test details for Chronic Myelogenous Leukemia (CML) Profile: Chromosome Analysis and BCR-ABL, FISH.
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20 Philadelphia chromosome–like acute lymphoblastic leukemia
https://ashpublications.org/blood/article/130/19/2064/36686/Philadelphia-chromosome-like-acute-lymphoblastic
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as BCR-ABL1–like ALL, is a high-risk subset with a gene expression ...
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21 Chronic myeloid leukaemia (CML) tests for diagnosis
https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/chronic-myeloid-leukaemia/cml-symptoms-diagnosis/cml-tests/
In 95% of people with CML, the Philadelphia chromosome can be detected with a cytogenetic test. This would confirm a diagnosis of CML.
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22 Genomics and Hematologic Malignancies
https://www.lls.org/professional-education-webcasts/genomics-and-hematologic-malignancies-beyond-philadelphia
It has been 60 years since the discovery of a chromosomal abnormality in CML; the so-called Philadelphia chromosome. Since then genomics has revolutionized ...
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23 Leukemia - Chronic Myeloid - CML: Diagnosis | Cancer.Net
https://www.cancer.net/cancer-types/leukemia-chronic-myeloid-cml/diagnosis
For a small number of patients, increased blood cell counts may suggest CML, but the Philadelphia chromosome cannot be found on the usual tests even though the ...
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24 Philadelphia chromosome - Wikipedia
https://en.wikipedia.org/wiki/Philadelphia_chromosome
The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 · The presence of this translocation is ...
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25 BCR-ABL1 and the Philadelphia chromosome - Part 2
https://www.youtube.com/watch?v=25yj11Fefwo
Oct 4, 2021
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26 The Philadelphia Chromosome: History and Implications for ...
https://www.foxchase.org/about-us/history/discoveries-fox-chase-research/philadelphia-chromosome/philadelphia-chromosome
The abnormally shortened chromosome was discovered by both Hungerford, of the Fox Chase Cancer Center, and Nowell of the University of Pennsylvania, and was ...
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27 Every case of essential thrombocythemia should be tested for ...
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.20257
ª 2004 Wiley-Liss, Inc. Key words: essential thrombocythemia; Philadelphia chromosome; thrombocytosis; chronic myelogenous leukemia. INTRODUCTION. Essential ...
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28 BCR-ABL - Lab Tests Online-UK
https://labtestsonline.org.uk/tests/bcr-abl
Testing for BCR-ABL detects the Ph chromosome (the derivative chromosome 22) and BCR-ABL fusion gene or its transcripts, the RNA copies made by ...
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29 Chronic Myeloid Leukemia (CML) - Penn Medicine
https://www.pennmedicine.org/cancer/types-of-cancer/leukemia/types-of-leukemia/chronic-myeloid-leukemia
When you are diagnosed, your physicians will request testing to find out if you have the Philadelphia chromosome or Bcr-Abl. New, targeted treatments have been ...
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30 What is CML (Ph+ Chronic Myeloid Leukemia)? - Tasigna
https://www.us.tasigna.com/about-ph-cml/understanding-cml/
Philadelphia chromosome–positive chronic myeloid leukemia (Ph+ CML) · Ph+ CML may seem to come out of nowhere. After a routine blood test, your doctor tells you ...
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31 BCR/ABL1 t(9;22) - NeoGenomics Laboratories
https://neogenomics.com/test-menu/bcrabl1-t922
Philadelphia chromosome, Philadelphia translocation. Methodology. FISH. Test Description. Probes: ABL1 (9q34); ASS1 (9q34; BCR (22q11.2)
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32 Tests for Chronic Myeloid Leukemia - American Cancer Society
https://www.cancer.org/cancer/chronic-myeloid-leukemia/detection-diagnosis-staging/how-diagnosed.html
Some sort of gene testing will be done to look for the Philadelphia chromosome and/or the BCR-ABL gene. This type of test is used to confirm ...
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33 What You Need to Know about Philadelphia Chromosome ALL
https://www.healthline.com/health/leukemia/philadelphia-chromosome-all
Polymerase chain reaction (PCR) test. A PCR test can detect even small amounts of Philadelphia chromosomes not identifiable with other tests.
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34 Simple and reliably sensitive diagnosis and monitoring of ...
https://www.nature.com/articles/2401383
Philadelphia (Ph) chromosome or the bcr/abl fusion gene is the hallmark of chronic myeloid leukemia (CML) and serves as a prognostic marker ...
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35 New Order Codes for BCR-ABL Testing
https://wardelab.com/warde-reports/changes-to-bcr-abl-test-ordering/
On November 16, 2021, Warde Medical Laboratory will begin performing in-house RT-PCR testing for the BCR-ABL molecular rearrangements characteristic of ...
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36 Philadelphia Chromosome-like Acute Lymphoblastic ...
https://rushlab.testcatalog.org/show/PHLDF
This test is intended to be ordered when the entire Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like B-cell ALL) fluorescence in situ ...
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37 BCR-ABL1, Minor (p190), Quantitative
https://ltd.aruplab.com/Tests/Pub/2005016
Use in cases of Philadelphia chromosome positive (Ph+) lymphoblastic leukemia to quantify the BCR-ABL1 ...
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38 BCR-ABL1 Gene Rearrangement, Quantitative, PCR
https://jdos.nicholsinstitute.com/dos/lsa/test/421959
The Philadelphia Chromosome (Ph) is a translocation between chromosome 9 and 22 t(9; 22) (q34; Q11) that is found in more than 90-95% of chronic myeloid ...
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39 BCR-ABL Testing by Polymerase Chain Reaction in Patients ...
https://ascopubs.org/doi/10.1200/JOP.2016.014449
CML results from reciprocal t(9; 22)(q34; q11.2), called the Philadelphia chromosome. The most common molecular finding in CML is a major ...
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40 BCR-ABL TRANSCRIPT QUANT - Dynacare
https://www.dynacare.ca/specialpages/secondarynav/find-a-test/nat/bcr-abl%C2%A0quantitative%C2%A0pcr%C2%A0blood?sr=ONT&st=
BCR-ABL testing is ordered to detect the BCR-ABL rearrangement, also known as the Philadelphia chromosome, to help diagnose and monitor chronic myeloid leukemia ...
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41 Clinical trial puts Philadelphia chromosome-positive leukemia ...
https://www.mdanderson.org/cancerwise/immunotherapy-and-targeted-therapy-clinical-trial-put-philadelphelphia-chromosome-positive-acute-lymphoblastic-leukemia-ALL-patient-in-remission.h00-159461634.html
When a genetic test revealed that Jorge Castillo had a particularly aggressive type of acute lymphoblastic leukemia called Philadelphia ...
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42 Genetic Testing | Children's Hospital of Philadelphia
https://www.chop.edu/treatments/genetic-testing
A chromosomal microarray (or array) is a type of genetic test that can detect changes in the number of genes. It looks for extra or missing portions of a ...
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43 BCR-ABL 1 Testing AHS – M2027 - Blue Cross NC
https://www.bluecrossnc.com/document/bcr-abl-1-testing-ahs-%E2%80%93-m2027
Chronic myeloid leukemia (CML) was the first human malignancy in which a specific chromosomal defect, known as the minute or Philadelphia (Ph) ...
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44 What Is Philadelphia Chromosome Positive ALL?
https://www.stbaldricks.org/blog/post/what-is-philadelphia-chromosome-positive-all/
Once a patient is diagnosed with ALL there are specialized tests that are performed to look inside the cancer cells at their specific genes.
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45 Chronic Myeloid Leukemia Tests - ClinLab Navigator
http://www.clinlabnavigator.com/chronic-myeloid-leukemia-tests.html
CML results from clonal expansion of a malignant hematopoietic stem cell carrying the Philadelphia chromosome (Ph). Ph chromosome is produced by a ...
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46 Diagnosing Chronic Myelogenous Leukemia
https://nyulangone.org/conditions/chronic-myelogenous-leukemia/diagnosis
A polymerase chain reaction test can detect the Philadelphia chromosome if a doctor isn't able to identify it via fluorescence in situ hybridization. In this ...
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47 BCR/ABL1 t(9;22) by FISH | Test Menu
https://www.mplnet.com/tests/bcr-abl9q34-t922-1
Test Code. F BCR ABL. Test Synonyms. Philadelphia chromosome, t(9;22)(q34;q11.2). Associations. Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic ...
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48 Tests for Acute Lymphoblastic Leukaemia (ALL)
https://www.cancercouncil.com.au/acute-lymphoblastic-leukaemia/diagnosis/tests-2/
A genetic test called FISH (fluorescence in situ hybridisation) can look for abnormal chromosomes (including the Philadelphia chromosome). A test called PCR ...
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49 Pathlogos - Philadelphia chromosome is definitive test for ...
https://m.facebook.com/pathlogos/photos/philadelphia-chromosome-is-definitive-test-for-diagnosis-of-chronic-myeloid-leuk/850718128736974/?locale2=vi_VN
Philadelphia chromosome is definitive test for diagnosis of chronic myeloid leukemia. The Philadelphia chromosome forms when chromosome 9 (carrying abl)...
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50 Karyotyping - UCSF Health
https://www.ucsfhealth.org/medical-tests/karyotyping
The bone marrow or blood test can be done to identify the Philadelphia chromosome, which is found in 85% of people with chronic myelogenous ...
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51 BCR/ABL/ASS1 t(9;22), CML - Incyte Diagnostics
https://www.incytediagnostics.com/laboratory-services/test-directory/TestDetails/bcrablass1-t922-cml
Updated Test Information: ; BCR/ABL/ASS1 t(9;22), CML · CML, ALL, MPN, Philadelphia chromosome, Philadelphia translocation · Probes: BCR (22q11.23)/ABL (9q34.12)/ ...
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52 Genetic testing used at diagnosis | CML Support
https://cmlsupport.org.uk/content/genetic-testing-used-diagnosis
Some sort of genetic testing will be done to look for the Philadelphia chromosome and/or the BCR-ABL1 gene. The following types of tests can confirm or deny ...
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53 Monitoring Ph+ CML Treatment | SPRYCEL® (dasatinib)
https://www.sprycel.com/monitoring-treatment
Ongoing testing and monitoring is very important to help you and your doctor understand if your Philadelphia chromosome–positive chronic myeloid leukemia ...
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54 Philadelphia Chromosome: Leukemia and Identifying Cancer
https://www.verywellhealth.com/what-is-the-philadelphia-chromosome-2252562
The Philadelphia chromosome is a specific finding in the genes of a person's white blood cells—a finding that has implications for leukemia.
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55 Rare Finding in Acute Lymphocytic Leukemia - Oxford Academic
https://academic.oup.com/labmed/article/44/2/e22/2657853
... with Philadelphia chromosome. Physical Exam Findings: ... Philadelphia chromosome, acute lymphoblastic leukemia, hematology, pre-B-cell.
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56 Philadelphia Chromosome Positive Acute Lymphoblastic ...
https://massivebio.com/philadelphia-chromosome-positive-acute-lymphoblastic-leukemia/
These tests are used to see whether there are any alterations in the cancer that could make it more or less responsive to cancer-fighting ...
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57 BCR/ABL p190, Quant by RT PCR - UW Laboratory Test Guide
https://testguide.labmed.uw.edu/view/QP190?tabs=no
The Philadelphia chromosome (Ph) is the product of the reciprocal translocation between the ABL1 gene on chromosome 9, and the BCR gene on ...
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58 When the Philadelphia Chromosome Strikes
https://strandls.com/philadelphia-chromosome-strikes/
The BCR-ABL1 mutation also known as the Philadelphia chromosome or Philadelphia translocation (Ph) is a genetic abnormality in chromosome 22. There is a ...
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59 BCR/ABL1 PCR - Sonic Genetics
https://www.sonicgenetics.com.au/our-tests/all-tests/bcrabl1-pcr/
This BCR-ABL quantitative PCR test detects the e13a2 (b2a2) and e14a2 (b3a2) fusion transcripts (aka 'M-bcr' transcripts, which result in the P210 protein ...
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60 Use of PCR Testing in Chronic Myeloid Leukemia
https://www.hematologyandoncology.net/archives/december-2015/use-of-pcr-testing-in-chronic-myeloid-leukemia/
EJ CML is characterized by the 9;22 translocation. Two genes, BCR and ABL1, combine to create the BCR-ABL1 oncogene, a driver event in CML. This abnormality is ...
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61 Acute Lymphoblastic Leukemia - Genomic Testing Cooperative
https://genomictestingcooperative.com/acute-lymphoblastic-leukemia/
Philadelphia chromosome-positive (Ph1) ALL is one of the subtypes of ALL that is characterized by t(9;22)(q34;q11) and produces ...
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62 Molecular Diagnosis of the Philadelphia Chromosome in ...
https://www.tandfonline.com/doi/pdf/10.3109/10428198909042452
DETECTION OF THE PHILADELPHIA. CHROMOSOME. Use of the bcr test for the clinical diagnosis of CML and Ph' + ALlL. As nearly all CML patients have chromosome ...
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63 Chronic myeloid leukemia: cytogenetics and molecular ...
https://jmhg.springeropen.com/articles/10.1186/s43042-022-00248-2
On a cytogenetic level, it is characterized by the presence of the Philadelphia chromosome, originating from a balanced reciprocal translocation ...
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64 Chronic Myeloid Leukemia Screening and Diagnosis
https://cancer.osu.edu/for-patients-and-caregivers/learn-about-cancers-and-treatments/cancers-conditions-and-treatment/cancer-types/chronic-myeloid-leukemia/screening-and-diagnosis
Gene testing determines whether or not a patient has the Philadelphia chromosome. This chromosome is found in 95 percent of CML patients, and it causes the ...
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65 Genetic Testing - CML (Chronic myeloid leukemia) - IVAMI
https://www.ivami.com/en/genetic-testing-human-gene-mutations-diseases-neoplasias-and-pharmacogenetics/5034-genetic-testing-chronic-myelogenous-leukemia-chronic-myeloid-leukemia-genes-bcr-abl1-chromosome-9-and-chromosome-22
Genetic Testing - Chronic Myelogenous Leukemia (Chronic myeloid leukemia) - Genes BCR, ABL1, chromosome 9 and chromosome 22.
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66 Karyotyping Information | Mount Sinai - New York
https://www.mountsinai.org/health-library/tests/karyotyping
This test can: ... This test may be done: ... The bone marrow or blood test can be done to identify the Philadelphia chromosome, which is found in 85% of people ...
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67 Genetics, Philadelphia Chromosome Article - StatPearls
https://www.statpearls.com/articlelibrary/viewarticle/114117/
[2] Philadelphia chromosome is the hallmark of chronic myeloid leukemia ... Philadelphia chromosome is detectable with cytogenetic testing, ...
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68 BCR/ABL - Quantitative (Philadelphia Chromosome)
https://rtdiagnostics.net/bcrabl-quantitative-philadelphia-chromosome-
BCR –ABL is a gene Sequence located in the abnormal Chromosome on people with Leukemia. This test examines the gene sequence to detect Chronic Myelogenous ...
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69 BCR::ABL1 – FISH (Dx)
https://cancergeneticslab.ca/hematological/cml/cml-fish-dx/
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm, predominantly affecting granulocytes, whereas Philadelphia positive acute ...
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70 Philadelphia Chromosome (BCR/ABL Qualitative) | Pathkind
https://www.pathkindlabs.com/diagnostic/philadelphia-chromosome-bcr-abl-qualitative
Philadelphia Chromosome (BCR/ABL Qualitative) · For Patients · Clinical History · Sample Cut off : 8:00 AM (Sun, Wed), Report : Mon, Thurs 7:30 PM (NOTE:TAT will ...
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71 Chronic Myelogeneous Leukemia - Johns Hopkins Medicine
https://www.hopkinsmedicine.org/kimmel_cancer_center/cancers_we_treat/leukemia_program/chronic_myelogenous_leukemia.html
The diagnosis is usually confirmed by finding the Philadelphia chromosome in the cells. In some cases, special molecular tests are required to detect an ...
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72 Chromosomal Abnormalities and Genetic Alterations in CML
https://www.onclive.com/view/chromosomal-abnormalities-and-genetic-alterations-in-cml
The 1 most commonly used is a test known as polymerase chain reaction amplification, which amplifies the BCR-ABL transcripts specifically.
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73 Clinical Trials - Dana-Farber Cancer Institute
https://www.dana-farber.org/clinical-trials2/detail/17-737/
INTERNATIONAL PHASE 3 TRIAL IN PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA (PH+ ALL) TESTING IMATINIB IN COMBINATION WITH TWO DIFFERENT ...
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74 Philadelphia chromosome-positive B-lymphoblastic ...
https://journals.lww.com/md-journal/Fulltext/2021/06110/Philadelphia_chromosome_positive_B_lymphoblastic.70.aspx
FISH testing showed the BCR/ABL positive cells were 13.6%. Karyotype analysis showed the 46, XY, t(9;22)(q34;q11).
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75 Cryptic BCR-ABL fusion gene as variant rearrangement in ...
https://www.oncotarget.com/article/15369/text/
At diagnosis, about 5% of Chronic Myeloid Leukemia (CML) patients lacks Philadelphia chromosome (Ph), despite the presence of the BCR/ABL ...
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76 Detection of BCR-ABL Positive Cells in an Asymptomatic Patient
https://www.hindawi.com/journals/crim/2010/939706/
Luppi et al., “Chronic myelogenous leukemia with typical clinical and morphological features can be Philadelphia chromosome negative and “bcr negative”,” ...
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77 Dasatinib in Imatinib-Resistant Philadelphia Chromosome ...
https://www.nejm.org/doi/full/10.1056/nejmoa055229
The BCR-ABL tyrosine kinase inhibitor imatinib is effective in Philadelphia chromosome–positive (Ph-positive) leukemias, but relapse occurs, ...
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78 Medline ® Abstract for Reference 45 of 'Clinical manifestations ...
https://www.uptodate.com/contents/clinical-manifestations-pathologic-features-and-diagnosis-of-b-cell-acute-lymphoblastic-leukemia-lymphoma/abstract/45
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) ... available diagnostic testing modalities, and current clinical treatment ...
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79 Philadelphia Chromosome (BCR/ABL) (Leukemia) Biomarker ...
https://www.contractlaboratory.com/directory/laboratories/by-testing-type.cfm?Philadelphia-Chromosome-(BCR/ABL)--(Leukemia)-Biomarker-Testing-Laboratories&i=1349
Testing and Scientific Research Areas · Laboratory Directory · Laboratories by Testing Types · Philadelphia Chromosome (BCR/ABL) (Leukemia) Biomarker Testing ...
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80 The Clinical Significance of BCR-ABL1 Mutations in Patients ...
https://www.astctjournal.org/article/S2666-6367(22)00156-7/fulltext
The outcomes of Philadelphia chromosome–positive chronic myeloid leukemia ... Fisher's exact test and the Mann–Whitney U test were used to ...
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81 Karyotyping | UF Health, University of Florida Health
https://ufhealth.org/karyotyping
The bone marrow or blood test can be done to identify the Philadelphia chromosome, which is found in 85% of people with chronic myelogenous ...
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82 AALL1631 - Clinical Trials - UI Health Care
https://clinicaltrials.uihealthcare.org/studies/aall1631-international-phase-3-trial-philadelphia-chromosome-positive-acute-lymphoblastic
Home · Studies · AALL1631 : International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ ALL Testing Imatinib in Combination ...
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83 Treatment of Philadelphia Chromosome-Positive Acute ... - MDPI
https://www.mdpi.com/2072-6694/14/7/1805/htm
Philadelphia-chromosome positive acute lymphoblastic leukemia (Ph+ ALL) is the most common subtype of B-ALL in adults and its incidence increases with age. It ...
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84 Leukocyte Alkaline Phosphatase and the Philadelphia ...
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/573447
CHRONIC myelogenous leukemia (CML) is the only malignancy in which a specific and consistent chromosome abnormality has been consistently documented.1 This ...
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85 chromosome analysis, hematologic malignancy, pediatrics
https://www.geisingermedicallabs.com/catalog/details.cfm?tid=442
... for medical laboratory test CHROMOSOME ANALYSIS, HEMATOLOGIC MALIGNANCY, ... Leukemia (ALL),Chronic Myelogenous Leukemia (CML),Philadelphia Chromosome.
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86 BCR-ABL One-Step Detection Kit | EntroGen, Inc.
http://entrogen.com/web3/bcr-abl-one-step-detection-kit/
› web3 › bcr-abl-one-step-detectio...
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87 Prevalence of atypical BCR-ABL1 transcript types in adult ...
http://www.htct.com.br/en-prevalence-atypical-bcr-abl1-transcript-types-articulo-S2531137921000936
The BCR-ABL1 oncogene is the molecular hallmark of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ...
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88 Incidence of bcr‑abl fusion transcripts in healthy individuals
https://www.spandidos-publications.com/10.3892/mmr.2014.1951
Bcr‑abl fusion transcripts, resulting from translocation t(9;22), are hallmarks of Philadelphia chromosome positive (Ph+) leukemias.
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89 Research of the Philadelphia Chromosome in Chronic ...
https://www.intechopen.com/chapters/75070
The Philadelphia chromosome t(9;22)(q34;q11) is the first cytogenetic abnormality that has been associated with a malignant process. It is found in 89 to 95% of ...
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90 CML (Karyotype) Test - Test Results, Normal Range, Cost And ...
https://www.lybrate.com/lab-test/cml-karyotype
This test is a more sensitive way to find CML than the standard cytogenetic tests that recognize the Philadelphia chromosome. ... PCR tests may also be used to ...
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91 What Is the Role of HSCT in Philadelphia-Chromosome ...
https://www.frontiersin.org/articles/10.3389/fped.2021.807002/full
Philadelphia-chromosome–positive (Ph+) acute lymphoblastic leukaemia (ALL) and, more recently, also Philadelphia-chromosome–like (Ph-like; also known as BCR-ABL ...
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92 2913 Low Level BCR-ABL1 Gene Fusion Detected By RT ...
https://ash.confex.com/ash/2020/webprogram/Paper139359.html
The Philadelphia chromosome t(9;22), a reciprocal translocation between chromosomes 9 and 22, results in the gene fusion BCR-ABL1, ...
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93 00428 BCR-ABL1 Testing in Chronic Myelogenous Leukemia ...
https://www.bcbsla.com/-/media/Medical%20Policies/2020/08/03/17/33/BCRABL1TestinginChronicMyelogenousLeukemiaandAcuteLymphoblasticLeukemia.pdf
monitoring of Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL) treatment response and remission to be eligible for ...
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94 BCR-ABL Test - DoveMed
https://www.dovemed.com/common-procedures/procedures-laboratory/bcr-abl-test/
The BCR-ABL Tests are used to look for the BCR-ABL fusion gene and Philadelphia chromosome, or the product of the abnormal gene. These tests may ...
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95 Is Philadelphia Chromosome Curable? - eMedicineHealth
https://www.emedicinehealth.com/is_philadelphia_chromosome_curable/article_em.htm
How Is Philadelphia Chromosome Diagnosed? · Blood cell counts. Complete blood count (CBC); Bone marrow test; Blood chemistry tests · Genetic tests.
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96 Philadelphia Chromosome (BCR/ABL Quantitative) in Gopalgunj
https://redcliffelabs.com/gopalgunj/tests/philadelphia-chromosome-bcr-abl-quantitative
Philadelphia Chromosome (BCR/ABL Quantitative) in Gopalgunj ; Fasting No fasting Required ; Get Reports in 7 days ; Home Collection Available ; Age Group 0-99 years.
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97 International Phase 3 Trial in Philadelphia Chromosome ...
https://www.kucancercenter.org/cancer-clinical-trials/find-trial/clinical-trial-results/nct03007147
International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Ph+ALL Testing Imatinib in Combination with Two Different Cytotoxic ...
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