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1 People - Alumni - David Baltimore - Whitehead Institute
https://wi.mit.edu/people/alumni/baltimore
Baltimore is now the President Emeritus and Distinguished Professor of Biology at the California Institute of Technology.
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2 David Baltimore – Biographical - NobelPrize.org
https://www.nobelprize.org/prizes/medicine/1975/baltimore/biographical/
This observation led to the development of Gleevec, one of the most successful anti-cancer drugs and the first small molecule to target the activity of an ...
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3 David Baltimore - Wikipedia
https://en.wikipedia.org/wiki/David_Baltimore
David Baltimore (born March 7, 1938) is an American biologist, university administrator, ... anti-cancer drug Imatinib (Gleevec), which deactivates bcr-abl proteins.
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4 Sixty Years of Discovery | Annual Review of Immunology
https://www.annualreviews.org/doi/10.1146/annurev-immunol-042718-041210
David Baltimore. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA; ...
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5 David Steensma, MD on Twitter: "The drug name, Glivec or Gleevec ...
https://twitter.com/davidsteensma/status/1199415185003483136
Dean, but back then working in David Baltimore's lab - and his colleagues definitively showed BCR/ABL was oncogenic by using it to generate leukemia in some ...
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6 The Relevant Biomedical Research - | Harvard Magazine
https://www.harvardmagazine.com/2007/01/the-relevant-biomedical.html
But in the early 1970s, Temin and David Baltimore, who had also worked with Dulbecco ... The crystal structure of kit, showing how Gleevec (imatinib) blocks ...
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7 Gleevec's - Employees Csbsju
https://employees.csbsju.edu/hjakubowski/classes/medew/pdfs/gleevec.pdf
days of the Gleevec story and now an hhmi investigator at the Uni- ... he joined his former boss, David Baltimore, now president of the Cal-.
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8 Fundamental discoveries, academic leadership, and public ...
https://laskerfoundation.org/winners/fundamental-discoveries-academic-leadership-public-advocacy/
The 2021 Lasker~Koshland Award for Special Achievement in Medical Science honors David Baltimore (California Institute of Technology), ...
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9 ARIAD Press Release - Media Corporate IR Net
http://media.corporate-ir.net/media_files/nsd/aria/releases/070703.pdf
key cancer-causing protein responsible for Gleevec's efficacy. Furthermore, unlike Gleevec, AP23464 is designed to block ... Dr. David Baltimore's.
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10 Destroying Dogma: the Discovery of Reverse Transcriptase
https://centennial.rucares.org/index.php?page=destroying_dogma
In 1970 David Baltimore (1938- ) made a profound discovery that contradicted ... groundwork for the development of the successful anti-cancer drug Gleevec.
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11 CV - David Baltimore | Lindau Mediatheque
https://mediatheque.lindau-nobel.org/laureates/baltimore/cv
David Baltimore received the Nobel Prize in Physiology or Medicine at the ... Their work also led to the development of the anti-cancer drug Gleevec.
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12 2006 Judson Daland Prize - American Philosophical Society
https://www.amphilsoc.org/2006-judson-daland-prize
... the HST division) in the laboratory of David Baltimore, George Daley created ... the remarkably effective inhibitor of the fusion gene product, Gleevec.
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13 David Baltimore - Wikipedia - Index of /
https://static.hlt.bme.hu/semantics/external/pages/John_McCarthy/en.wikipedia.org/wiki/David_Baltimore.html
David Baltimore (born March 7, 1938) is an American biologist, ... Gleevec has shown impressive results in treating chronic myelogenous ...
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14 Imatinib Mesylate (Gleevec) | Top Drugs - Oxford Academic
https://academic.oup.com/book/40715/chapter/348465971
Imatinib mesylate (1, Gleevec) is a protein-tyrosine kinase inhibitor for the treatment of ... In 1970, Herbert Abelson, working with David Baltimore, ...
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15 Translational research: are we on the right track? - PMC - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575723/
This search eventually led to the identification of imatinib mesylate ... working with David Baltimore, performed some of the most critical studies ...
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16 CML
https://www.lls.org/sites/default/files/chapters/noh/Pdf/OH%20BCC%20-%20CML%20-%20Dr%20%20van%20Heeckeren.pdf
David Baltimore PhD (Molecular biologist) ... 2001: FDA Approval of Gleevec for CML ... of imatinib compared to 68% of patients alive at.
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17 Alex Matter: Making Targeted Therapy a Reality - NFCR
https://www.nfcr.org/blog/szent-gyorgyi-prize-matter-gleevec/
Gleevec, also known as Glivec, is the brand name of imatinib mesylate, ... Working with this virus, David Baltimore's group demonstrated the ...
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18 Cracking Down on Cancer: A Profile of Owen Witte
https://www.the-scientist.com/profile/cracking-down-on-cancer-a-profile-of-owen-witte--67314
“I kind of laughed because David Baltimore had won the Nobel Prize about two years prior, and I was sure that the lineup of people trying to ...
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19 Owen Witte, MD - SOFIE
https://sofie.com/team/owen-witte/
... Institute of Technology with Nobel laureate, David Baltimore. ... of the preclinical discoveries that led to the development of Gleevec, ...
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20 Dedicated to discovering why normal cells turn malignant
https://www.ucihealth.org/blog/2018/05/richard-van-etten
One October morning in 1975, American biologist David Baltimore — who was ... That compound eventually became Gleevec, a miracle pill that ...
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21 David Baltimore - The American Association of Immunologists
https://www.aai.org/About/History/Notable-Members/Nobel-Laureates/DavidBaltimore
David Baltimore, California Institute of Technology (Caltech), was awarded the 1975 Nobel Prize for Physiology or Medicine jointly with Renato Dulbecco and ...
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22 Caltech, UCLA Launch Joint Center for Translational Medicine
https://hr.caltech.edu/news/caltech-ucla-launch-joint-center-translational-medicine-1585
... discoveries from research into clinical practice," says David Baltimore, ... targeted drugs Herceptin, Gleevec, Avastin, and Sprycel.
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23 Efficacy and Safety of a Specific Inhibitor of the BCR-ABL ...
https://www.nejm.org/doi/full/10.1056/nejm200104053441401
... Gregory Burke, David Parkinson, Michael Hayes, Ulrike Zoellner, ... Daley GQ, Van Etten RA, Baltimore D. Induction of chronic ...
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24 Gleevec's Glory Days - Howard Hughes Medical Institute
https://www.hhmi.org/sites/default/files/Bulletin/2001/December/dec2001_fulltext.pdf
issue is about Gleevec, an anticancer drug that was approved by the ... he joined his former boss, David Baltimore, now president of the Cal-.
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25 'I Love the Q' | Harvard Medical School
https://hms.harvard.edu/news/i-love-q
... cause and paving the way for the “magic bullet” drug Gleevec. ... David Baltimore was always about asking the important question.
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26 Powerful Anti-Cancer Drug Emerges from Basic Biology
https://www.nytimes.com/2001/05/08/science/powerful-anti-cancer-drug-emerges-from-basic-biology.html
If successful, Gleevec will be among the first fruits of some three ... Some 25 years later, Dr. David Baltimore, now president of Caltech ...
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27 A lily worth gilding - ScienceDirect.com
https://www.sciencedirect.com/science/article/pii/S0092867421009508
And David Baltimore is no ordinary lily. ... became the target for Brian Druker and Nick Lydon's drug imatinib (now Novartis' Gleevec), ...
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28 Treatment for chronic myelogenous leukemia: the long road to ...
https://www.jci.org/articles/view/31691
... Witte and David Baltimore identified the protein product of the BCR-ABL ... Yet another line of research pertinent to the imatinib story ...
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29 A Study of Ponatinib Versus Imatinib in Adults With Acute ...
https://clinicaltrials.gov/ct2/show/NCT03589326
› show › NCT03589326
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30 Press Releases - Gilead Sciences
https://www.gilead.com/news-and-press/press-room/press-releases/2017/3/kite-announces-appointment-of-renowned-cancer-researcher-owen-n-witte-md-to-its-board-of-directors
... including Gleevec® (imatinib) and Imbruvica® (ibrutinib). ... working in the lab of Nobel Laureate, David Baltimore , Ph.D. He also ...
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31 21st-century oncology: a tangled web - The Lancet
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(13)62660-4.pdf
has been the astonishing success of imatinib for chronic myelogenous leukaemia (CML). ... Nobel Prize winner David Baltimore reproduced CML.
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32 Owen Witte | Warren Alpert Foundation Prize
https://warrenalpert.org/prize-recipients/owen-witte
He currently holds the UCLA David Saxon Presidential Chair in Developmental Immunology. ... Institute of Technology with Nobel laureate, David Baltimore.
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33 Imatinib Mesylate (Gleevec) - Basicmedical Key
https://basicmedicalkey.com/imatinib-mesylate-gleevec/
In 1970, Herbert Abelson, working with David Baltimore, isolated a transforming gene from a specific variant of the Moloney leukemia virus.
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34 How Irv Weissman learned to figure things out | News Center
https://med.stanford.edu/news/all-news/2016/01/how-irv-weissman-learned-to-figure-things-out.html
... longtime friends David Baltimore, PhD, and Leroy Hood, MD, PhD. ... anti-cancer medication Gleevec that would give a higher return on ...
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35 January 21, 2005 - Johns Hopkins Medicine
https://www.hopkinsmedicine.org/Press_releases/2005/01_21_05.html
... studying why the wonder-drug Gleevec doesn't work for everyone, ... 10:45 - 11:30 David Baltimore, California Institute of Technology
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36 Moral conundrum in medical research - Frontline - The Hindu
https://frontline.thehindu.com/other/article30194823.ece
Interview with David Baltimore, co-recipient of the Nobel Prize in ... anti-cancer drug] Gleevec because it had a huge impact on people.
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37 Druker and Other Leukemia Pill Creators Honored by Harvard ...
https://news.ohsu.edu/2001/05/01/druker-and-other-leukemia-pill-creators-honored-by-harvard-medical-school-faculty
The Alpert Foundation recognizes David Baltimore, Ph.D., ... have led to the drug being submitted for FDA approval (as Gleevec) this year as ...
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38 A legacy of tyrosine - ASBMB
https://www.asbmb.org/asbmb-today/people/051120/a-legacy-of-tyrosine
Work by David Baltimore and by Owen Witte's group at the ... which was renamed imatinib and later marketed as Gleevec, entered human trials.
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39 Schlissel, Mark - Researchers @ Brown
https://vivo.brown.edu/display/msschlis
... postdoctoral research as a Bristol-Myers Cancer Research Fellow under David Baltimore at the Massachusetts Institute of Technology, Whitehead Institute.
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40 home0002 - Dr. David Baltimore (born 1938) - Google Sites
https://sites.google.com/housatonicits.com/home0002/research/david-baltimore-b1938
David Baltimore (born March 7, 1938) is an American biologist, ... of the anti-cancer drug Imatinib (Gleevec), which deactivates bcr-abl proteins.
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41 Harvard Medical School
http://www.bumc.bu.edu/gms/files/2013/09/10-29-13-Seminar-Bio.pdf
working with Nobelist Dr. David Baltimore, Dr. Daley demonstrated that the BCR/ABL ... Gleevec resistance and informed novel combination ...
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42 Chao Feature | University of California, Irvine
https://www.som.uci.edu/features/feature-chao-052914.asp
... of Nobel laureate David Baltimore at the Massachusetts Institute of Technology. ... for it with drugs such as Gleevec that target the abnormal protein.
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43 Preserving some sanity - Genome Biology
https://genomebiology.biomedcentral.com/track/pdf/10.1186/gb-2011-12-1-102.pdf
Gleevec and other Bcr-Abl kinase inhibitors thanks to the discovery by David Baltimore and others that survival of.
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44 Moving at the speed of science - Cancer Network
https://www.cancernetwork.com/view/moving-speed-science
... MD, at Stanford and David Baltimore, PhD, at the Massachusetts ... was the “big one” that led to the development of imatinib (Gleevec).
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45 Chronic myeloid leukemia: reminiscences and dreams
https://www.haematologica.org/article/view/7703
However, imatinib is far from perfect, with only approximately 60% of ... working with the Nobel laureate David Baltimore, showed that ...
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46 Gleevec | Leaders in Pharmaceutical Business Intelligence ...
https://pharmaceuticalintelligence.com/tag/gleevec/
Posts about Gleevec written by sjwilliamspa and 2012pharmaceutical. ... David A. Cheresh. ... Leukemia (Baltimore), 16: 2190-2196, 2002. CrossRefMedline.
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47 Imatinib induces durable hematologic and cytogenetic ...
https://ashpublications.org/blood/article/99/6/1928/53574/Imatinib-induces-durable-hematologic-and
Imatinib induced hematologic response in 82% of patients and sustained hematologic ... Dr David Parkinson and Dr Greg Burke provided invaluable support, ...
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48 The Joy of Discovery - The Medicine Maker
https://themedicinemaker.com/business-regulation/the-joy-of-discovery
David Baltimore, Nobel Laureate, President Emeritus and Robert Andrews Millikan ... It eventually led to the “miracle drug” Gleevec.
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49 Treatment for chronic myelogenous leukemia ... - Europe PMC
https://europepmc.org/articles/PMC1934577/
Treatment for chronic myelogenous leukemia: the long road to imatinib. ... Subsequent studies from groups led by Owen Witte and David Baltimore identified ...
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50 Bcr-Abl Expression Levels Determine the Rate of ...
https://aacrjournals.org/cancerres/article/65/19/8912/518309/Bcr-Abl-Expression-Levels-Determine-the-Rate-of
David J. Barnes; ... Imatinib mesylate (Gleevec), an inhibitor of the Bcr-Abl tyrosine kinase, is a well tolerated and highly effective ...
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51 Translational research: are we on the right track?
https://the-asci.org/static/asci_files/addresses/asci2008.pdf
of imatinib (Gleevec) in chronic myeloid leukemia. ... patients we treated with imatinib in the phase I study. ... Daley and David Baltimore (10).
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52 gleevec definitions - RhymeZone
https://www.rhymezone.com/r/d=gleevec
Gleevec is a revolutionary small-molecule drug that prevents and stops the growth of cancer cells in. ... —David Baltimore [Similar quotes, lyrics].
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53 Imatinib Mesylate (STI571)-Induced Cell Edge Translocation of ...
https://molpharm.aspetjournals.org/content/75/1/75.full.pdf?with-ds=yes
ABBREVIATIONS: CML, chronic myelogenous leukemia; STI571 [imatinib mesylate; Gleevec (US) or Glivec ... mutant, abl-KD, were provided by David Baltimore.
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54 Dr. David A. Tuveson: Decoding a Complex Disease
https://leadingdiscoveries.aacr.org/dr-david-a-tuveson-decoding-a-complex-disease/
At the time, new therapies were beginning to show activity in clinical trials, including imatinib (Gleevec) for patients with chronic myelogenous leukemia and ...
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55 About David Baltimore: American biologist (1938-) - PeoplePill
https://peoplepill.com/people/david-baltimore
David Baltimore (born March 7, 1938) is an American biologist, ... of the anti-cancer drug Imatinib (Gleevec), which deactivates bcr-abl proteins.
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56 How a Chicken Helped Solve the Mystery of Cancer
https://www.mskcc.org/news/how-chicken-helped-solve-mystery
... along with David Baltimore from the Massachusetts Institute of Technology, ... The first such targeted therapy was imatinib (Gleevec®), ...
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57 Oncogenes and the Revolution in Cancer Research
https://journals.sagepub.com/doi/pdf/10.1177/1947601909356102
and David Baltimore in 1970 turned the central dogma of ... So David Baltimore requested a sample of ... Development of Gleevec, Iressa, and.
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58 Proto-oncogenes to Oncogenes to Cancer - Nature
https://www.nature.com/scitable/topicpage/proto-oncogenes-to-oncogenes-to-cancer-883/
... in the laboratories of David Baltimore, Howard Tenin, and Renato Dulbecco. ... However, more long-term clinical studies using imatinib to treat CML ...
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59 Imatinib Mesylate as Add-on Therapy for Pulmonary Arterial ...
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.112.000765
Imatinib in Pulmonary Arterial Hypertension, a Randomized, Efficacy Study ... Paul Corris, David Kiely, Andrew Peacock, Joanna Pepke-Zaba; ...
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60 History of The Jackson Laboratory
https://www.jax.org/about-us/history
The Nobel Prize in Physiology or Medicine 1975: David Baltimore (member, ... colleagues discover a reason why some patients do not respond well to Gleevec, ...
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61 2010 Honorees - The Hope Funds for Cancer Research
http://www.hope-funds.org/honorees/2010-honorees/
... a seminal textbook that he co-wrote with David Baltimore and Harvey Lodish. ... Two examples are the use of Gleevec and Sutent in gastrointestinal ...
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62 Madison Health: HealthDay News
https://www.madison-health.com/healthdayarticle.php?id=5315
The first generic version of the cancer drug Gleevec (imatinib mesylate) has ... editing to change human inheritance," conference leader David Baltimore, ...
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63 CML Learning Programme - EBMT
https://www.ebmt.org/sites/default/files/migration_legacy_files/document/Chronic%20Myeloid%20Leukaemia%20%28CML%29%20Learning%20Programme_Module%201.ppt
With imatinib (and other TKI treatments) the survival in CML has improved from a median of 3 ... E. Cannani, David Baltimore and Owen Witte.
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64 Executive Summary of a Book: Magic Cancer Bullet
https://www.discoverymedicine.com/Benjamin-Yang/2009/05/23/executive-summary-of-a-book-magic-cancer-bullet/
In 1986 and 1987, Dr. David Baltimore, then at the Whitehead ... After 18 months of treatment with Gleevec, 89% of the patients had not ...
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65 Leadership Focus on Advancing Cancer Research and ...
https://jnm.snmjournals.org/content/jnumed/62/9/1178.full.pdf
ogy at the UCLA David Geffen School of Medicine. From 2001 ... like Gleevec. ... ago, David Baltimore, PhD, put T-cell receptor genes into hemato-.
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66 Decrypted - SciXplore - WordPress.com
https://scixplore.wordpress.com/simplified-research-papers/
David Baltimore spent the majority of his early life investigating the ... the development of Gleevec, a drug that revolutionized the treatment of CML.
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67 Constitutional Values: The Trials of Gleevec and Judicialized ...
https://read.dukeupress.edu/books/book/2331/chapter/920071/Constitutional-ValuesThe-Trials-of-Gleevec-and
It elaborates the legal history of an anticancer drug, Gleevec, ... David C. ,. Patel. Sonya S. , and. Markowitz. Lauri E. ... Baltimore, MD.
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68 Editors and Staff | Journal of Experimental Medicine
https://rupress.org/jem/pages/editors-and-staff
David Baltimore at MIT studying early B cell development. Next, she completed her postdoctoral fellowship with Dr. Norbert Perrimon where she developed high- ...
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69 Tumor lysis syndrome: Pathogenesis, clinical manifestations ...
https://www.uptodate.com/contents/tumor-lysis-syndrome-pathogenesis-clinical-manifestations-definition-etiology-and-risk-factors/print
Medicine (Baltimore) 1981; 60:218. ... lysis syndrome after starting treatment with Gleevec in a patient with chronic myelogenous leukemia.
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70 Imatinib treatment duration is related to decreased estimated ...
https://www.annalsofoncology.org/article/S0923-7534(19)38353-X/pdf
Patients and methods: One hundred five CML patients on imatinib therapy ... the Baltimore Longitudinal Study taking antihypertensives and/.
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71 Nonadherence to Imatinib in 25% of CML Patients Leads to ...
https://www.medscape.com/viewarticle/715040
Imatinib is used for front-line treatment in CML, ... come from a clinical trial involving 87 patients, which was conducted by David Marin, ...
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72 Economy 1992; The Year in Science - Charlie Rose
https://charlierose.com/videos/22499
Charlie Rose
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73 David Baltimore | Biography, Nobel Prize, & Facts | Britannica
https://www.britannica.com/biography/David-Baltimore
David Baltimore, (born March 7, 1938, New York, New York, U.S.), American virologist who shared the Nobel Prize for Physiology or Medicine in 1975 with ...
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74 Data aids Novartis push to replace Gleevec with Tasigna
https://www.fiercepharma.com/pharma/data-aids-novartis-push-to-replace-gleevec-tasigna
That's great news for Novartis: Gleevec is its second best-selling drug with ... More 'contamination issues' haunt Emergent in Baltimore, this time at its ...
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75 Targeted Treatment in Sarcoma Patients
https://www.hematologyandoncology.net/archives/december-2011/targeted-treatment-in-sarcoma-patients/
David M. Loeb, MD, PhD. Download PDF. David M. Loeb, MD, PhD ... Baltimore, Maryland ... Imatinib is a good example of this type of targeted therapy.
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76 Viral oncology's complicated path—from cancer as contagion ...
https://cancerhistoryproject.com/article/viral-oncologys-complicated-path-from-cancer-as-contagion-to-todays-immunotherapy/
David Baltimore, who at that point has already won his Nobel Prize for the ... The way that Baltimore decides to end that exchange is by saying, ...
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77 DNA Interactive Site Map
http://www.dnai.org/sitemap/
1970s · David Baltimore, Howard Martin Temin, Stanley Norman Cohen, Herbert W. Boyer, ... The Philadelphia chromosome, Bud's story, How Gleevec™ works.
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78 UC regents appoint Dr. Owen Witte University Professor
https://www.uclahealth.org/news/uc-regents-appoint-dr-owen-witte-university-professor
... of Technology in the lab of Nobel laureate Dr. David Baltimore. ... which treats several types of leukemia and lymphoma, and Gleevec, ...
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79 What Can Be the Why? | Frontiers Fall 2011
https://cancer.osu.edu/about/publications-and-reports/magazines-and-publications/frontiers/2011/fall/what-can-be-the-why
David Baltimore at the Massachusetts Institute of Technology, working independently of Temin and Dulbecco, also discovered reverse transcriptase.
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80 John Goldman obituary | Medical research | The Guardian
https://www.theguardian.com/science/2014/jan/13/john-goldman
When the highly targeted anti-leukaemia drug imatinib (marketed under ... laureate David Baltimore at the Whitehead Institute in Cambridge, ...
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81 Hitting the Target: How Druker's Persistence Helped Launch a ...
https://www.onclive.com/view/hitting-the-target-how-drukers-persistence-helped-launch-a-new-mode-of-attack
And, imatinib has been approved for the treatment of additional tumor ... was at the Dana-Farber Cancer Institute when David Baltimore, PhD, ...
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82 The Philadelphia Chromosome: A Genetic Mystery, a Lethal ...
https://www.amazon.com/Philadelphia-Chromosome-Improbable-Invention-Lifesaving-ebook/dp/B00BBF8FL4
That scientist, David Hungerford, had no way of knowing that he had stumbled upon the ... came together to lead to the discovery of Gleevec fit together.
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83 Ariad Pharmaceuticals Inc 2003 Current Report 8-K - SEC Report
https://sec.report/Document/0001157523-03-002771/
Furthermore, unlike Gleevec, AP23464 is designed to block additional leukemia ... Dr. David Baltimore's research group discovered the cancer-causing ...
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84 Dana-Farber Leadership Profiles | Boston, MA
https://www.dana-farber.org/about-us/leadership/
... at Dana-Farber Cancer Institute; and the David G. Nathan Professor of Pediatrics. ... including imatinib (Gleevec) in patients with the sarcoma known as ...
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85 Ariad's Day in Court | Science | AAAS
https://www.science.org/content/blog-post/ariad-s-day-court
But among the inventors on the NF-B patent are David Baltimore, ... the 20% workforce reduction) and the "10X better than Gleevec" '464' yet ...
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86 Management of Chronic Myeloid Leukemia in Advanced Phase
https://www.frontiersin.org/articles/10.3389/fonc.2019.01132/full
In a retrospective cohort of 809 patients treated with imatinib, ... Marks SM, Baltimore D, McCaffrey R. Terminal transferase as a predictor ...
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87 IMATINIB Drug Record - DGIdb
https://www.dgidb.org/drugs/IMATINIB
David et al., 2007, Durable responses to imatinib in patients with PDGFRB fusion gene-positive and BCR-ABL-negative chronic myeloproliferative disorders., ...
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88 [PDF] Influence of late treatment on how chronic myeloid leukemia ...
https://oa.mg/work/10.1590/s1807-59322009000800004
George Q. Daley, R A Van Etten, David Baltimore ... Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia.
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89 2004 National Health Research Forum
https://www.researchamerica.org/national-health-research-forum/2004-national-health-research-forum/
“For example, Dr. Brian Druker who is credited with developing Gleevec, received his early grants from the ACS. And, Dr. David Baltimore laid the groundwork ...
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90 Crystal Structures of ABL-Related Gene (ABL2) in Complex ...
https://pubs.acs.org/doi/10.1021/jm101506n
The structures of the ABL2 kinase domain in complex with imatinib and ... Goff, S. P.; Gilboa, E.; Witte, O. N.; Baltimore, D. Structure of ...
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91 MITF Offers Clues to Therapy of Various Malignancies
http://www.tandfonline.com/doi/pdf/10.4161/cbt.5.7.3156
together,” said David E. Fisher, M.D., Ph.D., a pediatric oncologist ... Sawyers said it's possible that Gleevec and Sprycel might be used.
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92 Early Administration of Imatinib Mesylate Reduces Plexiform ...
https://scholarworks.iupui.edu/bitstream/handle/1805/25855/nihms-1628720.pdf?sequence=1&isAllowed=y
Yang2,3, Kent A. Robertson1,2, David A. Ingram2, Jaishri O. Blakeley4, D. Wade Clapp2,* ... The Johns Hopkins University School of Medicine, Baltimore,.
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93 (PDF) Imatinib Mesylate — A New Oral Targeted Therapy
https://www.researchgate.net/publication/11492545_Imatinib_Mesylate_-_A_New_Oral_Targeted_Therapy
PDF | This review discusses the development and uses of imatinib mesylate, a protein tyrosine ... David G Savage at Columbia University.
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94 PRESS RELEASE: Cellzome: Powerful 'Finger-Printing ...
https://www.fiercebiotech.com/biotech/press-release-cellzome-powerful-finger-printing-technology-identifies-novel-targets-for
Gleevec's inhibition of DDR1 suggests fibrosis as a potential new indication. David Simmons, Chief Scientific Officer added:.
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95 David Baltimore - Alchetron, The Free Social Encyclopedia
https://alchetron.com/David-Baltimore
David Baltimore (born March 7, 1938) is an American biologist, ... Gleevec has shown impressive results in treating chronic myelogenous ...
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96 Targeted Therapies: A New Generation of Cancer Treatments
https://www.aafp.org/pubs/afp/issues/2008/0201/p311.html
DAVID E. GERBER, MD ... Some drugs (e.g., sorafenib [Nexavar], sunitinib [Sutent], imatinib [Gleevec], dasatinib [Sprycel]) have multiple ...
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