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1 Human NK Cells and Herpesviruses: Mechanisms of ... - NCBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788305/
(B) NK cells can efficiently kill opsonized Herpesvirus-infected cells through antibody-dependent cellular cytotoxicity (ADCC) via CD16 ...
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2 Herpesvirus Evasion of Natural Killer Cells | Journal of Virology
https://journals.asm.org/doi/10.1128/JVI.02105-17
NK cells are of particular importance in herpesvirus infections, which is illustrated by systemic and life-threatening herpesvirus disease ...
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3 Functional paralysis of human natural killer cells by ... - PLOS
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1007784
VZV is closely related to herpes simplex virus type 1 (HSV-1), with both being human alphaherpesviruses. As these viruses are distinct in the ...
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4 Mechanism of Recognition of Herpes Simplex Virus Type 1 ...
https://www.microbiologyresearch.org/content/journal/jgv/10.1099/0022-1317-69-11-2859?crawler=true
NK cells may recognize a host protein which, when expressed on cell membranes, is enhanced indirectly as a consequence of the infection or directly, because it ...
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5 Natural killer cells in antiviral immunity
https://www.nature.com/articles/s41577-021-00558-3
Natural killer (NK) cells play an important role in innate immune responses to viral infections. Here, we review recent insights into the ...
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6 Modulation of CD112 by the alphaherpesvirus gD protein ...
https://www.pnas.org/doi/10.1073/pnas.1409485111
Natural killer (NK) cells are key players in the innate response to viruses, including herpesviruses. In particular, the variety of viral strategies to modulate ...
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7 Recurrent Facial Herpes Simplex Infections in a 4 year Old ...
https://www.jacionline.org/article/S0091-6749(06)03471-3/abstract
The common feature of NK cell deficiency is an unusual susceptibility to acute and chronic herpes family viral infections. We report a case of functional NK ...
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8 Activation of NK cells in mice following corneal infection with ...
https://iovs.arvojournals.org/article.aspx?articleid=2160463
The role of natural killer cells (NK) in resistance to viral infections is controversial. The authors studied the influence of the Igh-1 locus on in vitro ...
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9 Human natural killer cells fail to kill herpes simplex virus type ...
https://www.sciencedirect.com/science/article/pii/S0143400405803406
Inversely, both HSV-infected and uninfected fibroblast cells demonstrated a competitive inhibition of NK cell lysis of K562 cells. The observed differences ...
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10 Natural Killer Cell Responses during Human γ-Herpesvirus ...
https://mdpi-res.com/d_attachment/vaccines/vaccines-09-00655/article_deploy/vaccines-09-00655-v2.pdf?version=1624013520
Abstract: Herpesviruses are main sculptors of natural killer (NK) cell ... NK cells, the human γ-herpesvirus Epstein–Barr virus (EBV) ...
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11 Re-evaluating the role of natural killer cells in innate ...
https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-56
Severe infections with herpesviruses such as herpes simplex virus type 1 (HSV-1) have been observed in natural killer (NK) cell-deficient ...
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12 The role of natural killer (NK) cells in ... - Wiley Online Library
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-3024.1980.tb00044.x
Interferon increases NK cell activity and NK cells inhibit viral replication. A correlation between resistance to HSV-I infection and NK cell activity of CBA or ...
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13 Combination of herpes-simplex based oncolytic viruses (HSV ...
https://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(19)31669-6/fulltext
Natural killer cells recognize and kill infected, stressed or malignant cells without prior antigen exposure. Patients who lack NK cells are highly susceptible ...
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14 ROLE OF NK CELLS IN PROTECTION OF MICE AGAINST ...
https://www.jimmunol.org/content/jimmunol/138/3/884.full.pdf
NK cells in protection against development of fatal HSV infec- tion in mice. A primary infection with herpes implex virus-1 (HSV-.
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15 Herpes Simplex Virus Antigens Directly Activate NK Cells via ...
https://journals.aai.org/jimmunol/article/188/9/4158/39623/Herpes-Simplex-Virus-Antigens-Directly-Activate-NK
NK cells infiltrate human herpetic lesions, but their role has been underexplored. HSV can stimulate innate immune responses via surface TLR2, ...
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16 Impaired neonatal natural killer-cell activity to herpes simplex ...
https://link.springer.com/article/10.1007/BF00918701
Human adult natural killer (NK) cells were recently demonstrated to inhibit herpes simplex virus (HSV) replicationin vitro. In this study we compared the ...
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17 Medline ® Abstract for Reference 72 of 'NK cell deficiency ...
https://www.uptodate.com/contents/nk-cell-deficiency-syndromes-clinical-manifestations-and-diagnosis/abstract/72
These data suggest that natural killer cells probably play an important role in human resistance to herpesvirus infection and that deficiencies of this system ...
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18 Natural Killer Cell Functional Defects in Pediatric Patients With ...
https://academic.oup.com/jid/article/207/3/458/876349
Natural killer (NK) cells play a critical role in the host defense against herpesviruses. Although herpesviruses are ubiquitous in human populations, ...
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19 Natural Killer Cell Deficiencies in a Consecutive Series of ...
https://journals.sagepub.com/doi/pdf/10.1177/039463201102400128
cohort of consecutive patients affected by severe herpes simplex infections. These findings suggest a role for NK cell deficiencies as a predisposing factor ...
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20 Anti-Interf eron Antibody Inhibits Natural Killer Cell Activity in ...
https://www.karger.com/Article/Pdf/150158
Herpes simplex virus type 2. Anti-interferon antibody. Natural killer cells. Summary. We reported previously that the administration of anti-α/β murine ...
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21 Taking the 'killer' out of natural killer cells - ScienceDaily
https://www.sciencedaily.com/releases/2019/06/190613143531.htm
In this way, VZV paralyses natural killer cells from functionally responding to target cells. The closely related virus, herpes simplex virus ...
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22 1544.pdf - Rockefeller University Press
https://rupress.org/jem/article-pdf/157/5/1544/1093427/1544.pdf
virus type 1; IFN, interferon; KOSdG, cells infected with herpes simplex virus type l, strain KOS, in the presence of 2dG; NK, natural killer; PBML, ...
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23 Human T Cell Clones and Nk Cells to Herpes Viruses
https://grantome.com/grant/NIH/R01-AI023249-01
Herpes viruses, including herpes simplex viruses (HSV), Epstein-Barr virus (EBV), herpes varicella-zoster (HVZ) and cytomegalovirus (CMV) may cause cancer ...
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24 New Study Reveals The Mechanism by which Viruses Cause ...
https://blog.creative-bioarray.com/new-study-reveals-the-mechanism-by-which-viruses-cause-nk-cell-spasm/
Herpes simplex virus type I is also effective in infecting NK cells and making natural killer cells unresponsive to target cell stimulation.
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25 Human NK Cells and Herpesviruses - Semantic Scholar
https://www.semanticscholar.org/paper/Human-NK-Cells-and-Herpesviruses%3A-Mechanisms-of-and-Chiesa-Maria/2843eb8744ef0e7171731dae2fd1f852b01172fe
Human Herpesvirus 6B Downregulates Expression of Activating Ligands during Lytic Infection To Escape Elimination by Natural Killer Cells · Human ...
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26 Herpes Simplex Virus-Infected Cells Disarm Killer Lymphocytes
https://www.jstor.org/stable/2354218
fibroblasts infected with herpes simplex viruses (HSVs) po- tently inhibit the lytic activity of natural killer cells and interleukin 2-activated killer ...
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27 Individual NK Cell Clones Lyse Both Tumor
https://www.liebertpub.com/doi/pdf/10.1089/vim.1990.3.217
Cell Targets and Herpes Simplex Virus-Infected ... We also showed that lysis of HSV-1 infected targets by NK cloned cells was independent of interferons in.
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28 Role of natural killer cells during herpes virus infection in a ...
https://www.uu.nl/sites/default/files/student_project_role_of_natural_killer_cells.pdf
Role of natural killer cells during herpes virus infection in a non mammalian host. Background: Herpesviruses are an ancient family of viruses that have ...
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29 Soluble Fc-Disabled Herpes Virus Entry Mediator Augments ...
https://lasid.org/soluble-fc-disabled-herpes-virus-entry-mediator-augments-activation-and-cytotoxicity-of-nk-cells-by-promoting-cross-talk-between-nk-cells-and-monocytes-innate-immunity-and-inflammation/
CD160 is highly expressed by NK cells and is associated with cytolytic effector activity. Herpes virus entry mediator (HVEM) activates NK cells for cytokine ...
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30 A herpesvirus encoded Qa-1 mimic inhibits natural killer cell ...
https://elifesciences.org/articles/38667
by X Wang · 2018 · Cited by 5 —
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31 The role of NK cells in fighting the virus infection and sepsis
https://www.medsci.org/v18p3236.htm
Natural killer (NK) cells are an important kind of innate immune cell and have been defined as “cytotoxic innate lymphoid cells (ILCs) with the capability of ' ...
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32 General rules regulating natural killer (NK) cell activity during...
https://www.researchgate.net/figure/General-rules-regulating-natural-killer-NK-cell-activity-during-herpes-simplex-virus_fig1_323124933
| General rules regulating natural killer (NK) cell activity during herpes simplex virus type 1 (HSV1) infection. NK cells express both inhibitory and ...
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33 The Role of Natural Killer Cells in Viral Infections
http://arconsultant.com/wp-content/uploads/2018/06/The-role-of-natural-killer-cells-in-viral-infections.pdf
in humans have suggested a vital role of NK cells in the host defence against human immunodeficiency virus, herpesviruses, hepatitis B and C and other ...
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34 Defects in interleukin-2 stimulation of neonatal natural killer ...
https://www.jpeds.com/article/S0022-3476(88)80229-4/abstract
Human recombinant IL-2-stimulated adult and cord blood NKC to herpes simplex virus-infected cells in a time-dependent and dose-dependent fashion.
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35 Herpes Simplex Virus Induces the Early Activation of NK Cell ...
https://openimmunologyjournal.com/VOLUME/3/PAGE/36/ABSTRACT/
In the course of a Herpes Simples Virus type-1 (HSV-1) infection, the bidirectional cross-talk between Natural Killer (NK) cells and Dendritic Cells (DCs) ...
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36 1 Ruxolitinib partially reverses functional NK cell deficiency in ...
https://www.biorxiv.org/content/10.1101/157271v1.full.pdf
papilloma virus.23-27, 30 Severe herpes viral infection with decreased NK cell. 122 natural cytotoxicity has been reported in patients with ...
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37 Assessing the binding of nectin-1 and CD96 in human cells to ...
https://rdw.rowan.edu/cgi/viewcontent.cgi?article=1006&context=buss
Role of nectin-1 in cell adhesion and NK cells . 1. Introduction. Nectin-1 is an adhesion protein that also serves as a receptor for herpes simplex virus.
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38 Herpes infections: Natural killer cells activate hematopoiesis
https://www.eurekalert.org/news-releases/583656
The new findings reveal a hitherto unsuspected link between natural killer (NK) cells and hematopoiesis. NK cells play an important role in ...
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39 The role of natural killer cells in fight against viral infections ...
https://www.news-medical.net/news/20210617/The-role-of-natural-killer-cells-in-fight-against-viral-infections-including-SARS-CoV-2.aspx
During a viral infection, the host cells may become vulnerable to NK cell-mediated recognition through the upregulation of self-encoded ...
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40 Imprint of human cytomegalovirus infection on the NK cell ...
https://ashpublications.org/blood/article/104/12/3664/89064/Imprint-of-human-cytomegalovirus-infection-on-the
Altogether, these data support that HCMV infection selectively shapes the natural killer cell receptor (NKR) repertoire of NK and T cells from healthy ...
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41 Herpes Simplex Virus Induces the Early ... - Bentham Open
https://benthamopen.com/ABSTRACT/TOIJ-3-36
Our results indicate that HSV TLRligands modulate the early NK: DC interaction and may be a mechanism used by these innate immune cells to ...
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42 Natural Killer (NK) Cell Activity of Mice Treated with ... - J-Stage
https://www.jstage.jst.go.jp/article/kurumemedj1954/37/4/37_4_229/_pdf
37, p. 229-234,. 1990. Natural Killer (NK) Cell Activity of Mice Treated with. Herpes Simplex Virus Type-2, Sarcoma-180 Cells,. Cyclosporine and Cimetidine.
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43 role of natural killer t cells (nkt) cells in immui{ity to herpes ...
https://digital.library.adelaide.edu.au/dspace/bitstream/2440/59216/2/02whole.pdf
3.2.2 Pathogenesis and clinical manifestations of primary HSV-l infection in Js18 GKO mice ..' 104. 3.2.3 The role of diverse NKT cells (Type lI) in control ...
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44 A combinational therapy of EGFR-CAR NK cells and oncolytic ...
https://dash.harvard.edu/bitstream/handle/1/29408262/5053686.pdf?sequence=1
therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases.” Oncotarget 7 (19): 27764-27777.
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45 A combinational therapy of EGFR-CAR NK cells ... - Oncotarget
https://www.oncotarget.com/article/8526/text/
A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases. Bookmark and Share.
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46 Journal of Neuroimmunology
https://www.jni-journal.com/article/S0165-5728(12)00216-0/pdf
Altered natural killer cells' response to herpes virus infection in multiple ... purified NK cells affected directly KIR2DL2 modulation and cell activation.
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47 Human herpesvirus 6A and 6B and NK cells in - AKJournals
https://akjournals.com/abstract/journals/030/65/2/article-p119.xml
The interactions between HHV-6 and NK cells have been scarcely studied, but it has become clear that NK cells are not only crucial in immune ...
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48 Full article: Recalcitrant Herpes Zoster Ophthalmicus in a ...
https://www.tandfonline.com/doi/full/10.1080/09273948.2020.1795205
Natural killer cells are a vital part of the innate immune response. These cells are especially important in the body's protection from viral ...
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49 The portal for rare diseases and orphan drugs - Orphanet
https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=437552
... immunodeficiency with defective spontaneous natural killer cell cytotoxicity ... herpes simplex virus, human papillomavirus), deficient spontaneous ...
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50 Natural Killer Cell Responses during Human γ ... - ProQuest
https://search.proquest.com/openview/86d4d8c4680f2f0717c02f668c86e3a8/1?pq-origsite=gscholar&cbl=2032320
Herpesviruses are main sculptors of natural killer (NK) cell repertoires. While the β-herpesvirus human cytomegalovirus (CMV) drives the accumulation of ...
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51 Treatment of Relapsing HPV Diseases by Restored Function ...
https://www.nejm.org/doi/full/10.1056/NEJMoa2102715
Allogeneic hematopoietic-cell transplantation led to restoration of NK cytotoxicity, with normalization of the skin microbiome and ...
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52 The role of natural killer (NK) cells in resistance to herpes ...
https://cris.bgu.ac.il/en/publications/the-role-of-natural-killer-nk-cells-in-resistance-to-herpes-simpl
Interferon increases NK cell activity and NK cells inhibit viral replication. A correlation between resistance to HSV‐I infection and NK ...
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53 Natural Killer Cell Evaluation and Research Clinic (NEAR)
https://www.columbiadoctors.org/childrens-health/pediatric-specialties/immunodeficiency-disorders/natural-killer-cell-evaluation-and-research-clinic-near
Suspected or diagnosed NK cell deficiency (NKD), classical NK cell deficiency (CNKD), ... Herpes simplex virus (HSV) – causes cold sores, genital herpes ...
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54 natural killer cell deficiency associated
http://www.fma.org.tw/jfma/PDF/2002-101/Issue%2001/A11.pdf
We report a case of NK cell deficiency with severe atopic dermatitis in infancy, bronchial asthma and recurrent herpes zoster infection in early childhood,.
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55 HUMAN HERPESVIRUS 6A AND 6B AND NK CELLS
http://real.mtak.hu/80911/1/030.65.2018.010.pdf
Both viral species are predominantly lymphotropic, infecting T lymphocytes and other lymphoid cells, including natural killer (NK) cells. The ...
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56 NK cells play a major role in the host-rejection of both tumours ...
https://www.facebook.com/PathologyDiscussionForum/videos/natural-killer-cellnk-cells-play-a-major-role-in-the-host-rejection-of-both-tumo/274792646726729/
adaptive immune response is generating antigen- specific cytotoxic T cells that can clear the infection. Patients deficient in NK cells prove to ...
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57 Herpes Simplex Virus - The Evasion Of Early Host Antiviral ...
https://www.oapublishinglondon.com/pop/herpes-simplex-virus/
Natural killer (NK) cells, on the other hand, are innate immunity cells capable of identifying and eliminating virus-infected cells that either ...
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58 Herpesviridae - Wikipedia
https://en.wikipedia.org/wiki/Herpesviridae
Human herpesvirus typesEdit ; HHV-4, Epstein–Barr virus (EBV) Lymphocryptovirus, γ (Gamma), B cells and epithelial cells ; HHV-5, Cytomegalovirus (CMV), β (Beta) ...
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59 NK Cell (Natural Killer Cell) Simplified: How it kills virus ...
https://www.youtube.com/watch?v=EkxpYtz8o-o
Apr 11, 2020
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60 Fundamental Immunology - Page 427 - Google Books Result
https://books.google.com/books?id=x0gpapT-Y2kC&pg=PA427&lpg=PA427&dq=herpes+nk+cells&source=bl&ots=XOcjI0B0Zb&sig=ACfU3U2QUmErKV6lZe7cvULmza1NT7ViPQ&hl=en&sa=X&ved=2ahUKEwjC1d2aouP7AhUwlWoFHQNEDssQ6AF6BQjMAhAD
Natural Killer Cells in Host Defense Against Pathogens While NK cells reportedly ... for severe or recurrent virus infections, particularly herpes viruses.
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61 Herpes Simplex Viruses 1 & 2 - Draw It to Know It
https://www.drawittoknowit.com/course/immunology/glossary/immunology-microbiology/herpes-simplex-viruses-1-2
— The ability to spread directly from cell-to-cell, which avoids immune cells and molecules; — HSV has antibody and complement receptors that ...
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62 How Herpes Simplex Virus Spreads
https://www.hsvherpes.com/howimmunistatworks.html
NK cells are activated in response to interferons or macrophage-derived cytokines. They serve to contain viral infections while the adaptive immune response is ...
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63 Sylvain Latour To cite this version - Archive ouverte HAL
https://hal.archives-ouvertes.fr/hal-03864240/document
few) T cells but normal B and NK cells. ... cytomegalovirus; HHV-8: human gamma herpes virus 8; TEMRA: terminally differentiated effector ...
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64 KEGG PATHWAY Database
https://www.genome.jp/kegg/pathway.html
Cellular Processes 5. Organismal Systems ... 04650: Natural killer cell mediated cytotoxicity ... 05167 N: Kaposi sarcoma-associated herpesvirus infection ...
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65 The Coronavirus, Epstein-Barr Virus and Chronic Fatigue ...
https://www.healthrising.org/blog/2022/11/27/epstein-barr-virus-reactivation-chronic-fatigue-syndrome/
Epstein-Barr virus (EBV) and other herpesvirus reactivation have been ... and/or that NK cells and T-cells exist in a state of exhaustion.
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66 Meet the Unsung Immune Cell that Could Change ...
https://www.mskcc.org/news/meet-unsung-immune-cell-could-change-immunotherapy
NK cells are naturally equipped to kill cells that lack these self-identifying molecules, which in most cases means virally infected cells.
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67 Medscape Video
https://www.medscape.com/video
... natural killer (NK) cells, including NK checkpoint inhibition and CAR NK ... NYU Langone Medical Center experts discuss the complex nature of herpes ...
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68 Search result for 'pregabalin for neuropathic pain in diabetes'
https://www.dovepress.com/search_results.php?search_word=pregabalin+for+neuropathic+pain+in+diabetes
Stress as Trigger Factor of HSV-1 Reactivation Causing Recurrent ... Poon JL, Wang Q, Mitchell BD, Peck EY, Babrowicz J, Raibulet NK, Child CJ, Beusterien K.
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70 Herpes - Page 18 - Google Books Result
https://books.google.com/books?id=poxhDwAAQBAJ&pg=PA18&lpg=PA18&dq=herpes+nk+cells&source=bl&ots=GzH75hyF4E&sig=ACfU3U07qNjCY6dgdSZkoYeF8rA1Rg3k_g&hl=en&sa=X&ved=2ahUKEwjC1d2aouP7AhUwlWoFHQNEDssQ6AF6BQi8AhAD
There are several factors that determine how virulent the herpes virus is. ... Two major types of cells that fight the HSV virus are natural killer (NK) ...
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