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Google Keyword Rankings for : restless leg syndrome is it genetic
1
Genetics of restless legs syndrome: An update - PubMed
https://pubmed.ncbi.nlm.nih.gov/29033051/
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS in ...
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https://pubmed.ncbi.nlm.nih.gov/29033051/
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS in ...
→ Check Latest Keyword Rankings ←
2
Restless Legs Syndrome
https://rarediseases.org/rare-diseases/restless-legs-syndrome/
In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain ...
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https://rarediseases.org/rare-diseases/restless-legs-syndrome/
In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain ...
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3
Is Restless Leg Syndrome Hereditary & What Can I Do?
https://www.usaveinclinics.com/blog/is-restless-leg-syndrome-hereditary/
Genetics: Is RLS hereditary? Restless legs syndrome and genetics appear to be correlated, as close to 50% of people suffering from RLS have ...
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https://www.usaveinclinics.com/blog/is-restless-leg-syndrome-hereditary/
Genetics: Is RLS hereditary? Restless legs syndrome and genetics appear to be correlated, as close to 50% of people suffering from RLS have ...
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4
MEIS1 and Restless Legs Syndrome: A Comprehensive Review
https://www.frontiersin.org/articles/10.3389/fneur.2019.00935/full
Restless legs syndrome (RLS) is a common sleep-related disorder for which the underlying biological pathways and genetic determinants are ...
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https://www.frontiersin.org/articles/10.3389/fneur.2019.00935/full
Restless legs syndrome (RLS) is a common sleep-related disorder for which the underlying biological pathways and genetic determinants are ...
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5
Restless Legs Syndrome: Confirmation of Linkage to ...
https://jamanetwork.com/journals/jamaneurology/fullarticle/788245
Genetic contributions to RLS have been consistently recognized from population, family, and twin studies. ... Familial aggregation has been particularly well ...
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https://jamanetwork.com/journals/jamaneurology/fullarticle/788245
Genetic contributions to RLS have been consistently recognized from population, family, and twin studies. ... Familial aggregation has been particularly well ...
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6
Causes of Restless Legs Syndrome (RLS)
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
RLS is also related to environmental factors and genes. The single largest known environmental factor is low iron levels, which may occur before birth, during ...
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https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/restless-legs-syndrome/what-is-rls/causes.html
RLS is also related to environmental factors and genes. The single largest known environmental factor is low iron levels, which may occur before birth, during ...
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7
Treatment for Restless Legs Syndrome Focuses on Relieving ...
https://newsnetwork.mayoclinic.org/discussion/treatment-for-restless-legs-syndrome-focuses-on-relieving-the-symptoms/
Restless legs syndrome, or RLS, is not always hereditary. But it does run in some families, and several genetic links have been found for RLS.
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https://newsnetwork.mayoclinic.org/discussion/treatment-for-restless-legs-syndrome-focuses-on-relieving-the-symptoms/
Restless legs syndrome, or RLS, is not always hereditary. But it does run in some families, and several genetic links have been found for RLS.
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8
Progress in the genetics of restless legs syndrome
https://academic.oup.com/sleep/article/45/8/zsac136/6604470
Twin and familial aggregation studies have suggested that genetic factors contribute up to 70% of the risk of developing RLS [3, 4]. Linkage ...
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https://academic.oup.com/sleep/article/45/8/zsac136/6604470
Twin and familial aggregation studies have suggested that genetic factors contribute up to 70% of the risk of developing RLS [3, 4]. Linkage ...
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9
Genetics of restless legs syndrome: An update - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S1087079217301545
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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https://www.sciencedirect.com/science/article/pii/S1087079217301545
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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10
Restless legs syndrome - Causes - NHS
https://www.nhs.uk/conditions/restless-legs-syndrome/causes/
Research has identified specific genes related to restless legs syndrome, and it can run in families. In these cases, symptoms usually occur before the age ...
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https://www.nhs.uk/conditions/restless-legs-syndrome/causes/
Research has identified specific genes related to restless legs syndrome, and it can run in families. In these cases, symptoms usually occur before the age ...
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11
Latest Perspectives in Genetic Risk Factors for Restless Legs ...
https://touchneurology.com/movement-disorders/journal-articles/latest-perspectives-in-genetic-risk-factors-for-restless-legs-syndrome/
The high frequency of positive family history of restless legs syndrome (RLS) in patients with this disease and the observed high concordance ...
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https://touchneurology.com/movement-disorders/journal-articles/latest-perspectives-in-genetic-risk-factors-for-restless-legs-syndrome/
The high frequency of positive family history of restless legs syndrome (RLS) in patients with this disease and the observed high concordance ...
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12
Restless Legs Syndrome (RLS): Causes, Symptoms, Diagnosis
https://my.clevelandclinic.org/health/diseases/9497-restless-legs-syndrome
Restless legs syndrome (RLS) has been found to be a genetic syndrome in some cases, meaning that parents with RLS can pass it down to their ...
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https://my.clevelandclinic.org/health/diseases/9497-restless-legs-syndrome
Restless legs syndrome (RLS) has been found to be a genetic syndrome in some cases, meaning that parents with RLS can pass it down to their ...
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13
Restless Legs Syndrome - 23andMe
https://www.23andme.com/topics/health-predispositions/restless-legs-syndrome/
Genetics does play a role in restless legs syndrome. In addition, people with a family history of RLS have a higher chance of developing RLS themselves.
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https://www.23andme.com/topics/health-predispositions/restless-legs-syndrome/
Genetics does play a role in restless legs syndrome. In addition, people with a family history of RLS have a higher chance of developing RLS themselves.
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14
Large genome-wide association study identifies three novel ...
https://www.nature.com/articles/s42003-020-01430-1
RLS is a complex polygenic sensorimotor disorder strongly influenced by lifestyle. This study increases the number of known independent RLS- ...
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https://www.nature.com/articles/s42003-020-01430-1
RLS is a complex polygenic sensorimotor disorder strongly influenced by lifestyle. This study increases the number of known independent RLS- ...
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15
Genetic Association Study of Restless Legs Syndrome in ...
https://www.karger.com/Article/Fulltext/500416
RLS has a well-defined phenotype, increased prevalence in the iron-deficient population and dramatic therapeutic response to dopamine-based ...
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https://www.karger.com/Article/Fulltext/500416
RLS has a well-defined phenotype, increased prevalence in the iron-deficient population and dramatic therapeutic response to dopamine-based ...
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16
MEIS1 and BTBD9: genetic association with restless leg ...
https://jmg.bmj.com/content/48/7/462
Restless legs syndrome (RLS) in end stage renal disease (ESRD) is a common form of symptomatic RLS and is associated with increased mortality and reduced ...
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https://jmg.bmj.com/content/48/7/462
Restless legs syndrome (RLS) in end stage renal disease (ESRD) is a common form of symptomatic RLS and is associated with increased mortality and reduced ...
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17
Restless legs syndrome study identifies 13 new genetic risk ...
https://www.cam.ac.uk/research/news/restless-legs-syndrome-study-identifies-13-new-genetic-risk-variants
A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform ...
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https://www.cam.ac.uk/research/news/restless-legs-syndrome-study-identifies-13-new-genetic-risk-variants
A new study into the genetics underlying restless legs syndrome has identified 13 previously-unknown genetic risk variants, while helping inform ...
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18
Gene Linked to Restless Leg Syndrome Found - ABC News
https://abcnews.go.com/Health/Healthday/story?id=4507985&page=1
"There is a strong familial and genetic basis to restless legs syndrome," said the author of an accompanying editorial, Dr. John Winkelman, medical director of ...
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https://abcnews.go.com/Health/Healthday/story?id=4507985&page=1
"There is a strong familial and genetic basis to restless legs syndrome," said the author of an accompanying editorial, Dr. John Winkelman, medical director of ...
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19
Genetics of restless legs syndrome | SpringerLink
https://link.springer.com/article/10.1007/s11910-008-0033-y
by J Winkelmann · 2008 · Cited by 83 —
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https://link.springer.com/article/10.1007/s11910-008-0033-y
by J Winkelmann · 2008 · Cited by 83 —
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20
Restless legs syndrome is in the genes
http://www.whsc.emory.edu/soundscience/archives/rye.html
“Restless legs is a genetic trait,” says Rye. “Nature loads the gun. Nuture pulls the trigger. Something happens to trigger it. It could be a neuropathy, it ...
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http://www.whsc.emory.edu/soundscience/archives/rye.html
“Restless legs is a genetic trait,” says Rye. “Nature loads the gun. Nuture pulls the trigger. Something happens to trigger it. It could be a neuropathy, it ...
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21
Causes and Risk Factors of Restless Legs Syndrome
https://www.verywellhealth.com/restless-legs-syndrome-causes-5069908
The most common cause of restless legs syndrome (RLS) is familial RLS, also known as primary RLS. Primary RLS is heritable and almost two-thirds ...
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https://www.verywellhealth.com/restless-legs-syndrome-causes-5069908
The most common cause of restless legs syndrome (RLS) is familial RLS, also known as primary RLS. Primary RLS is heritable and almost two-thirds ...
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22
Linking restless legs syndrome with Parkinson's disease
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Family history, with an autosomal dominant mode of inheritance may be present in more than half of the cases. Five genetic loci for RLS have ...
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https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-1-6
Family history, with an autosomal dominant mode of inheritance may be present in more than half of the cases. Five genetic loci for RLS have ...
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23
Entry - %612853 - RESTLESS LEGS SYNDROME ... - OMIM
https://www.omim.org/entry/612853
Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, ...
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https://www.omim.org/entry/612853
Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, ...
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24
Restless legs syndrome: is it all in the genes? - The Lancet
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30330-7/fulltext
The strongest association was found in MEIS1, a gene encoding a transcriptional regulator that has been implicated in the disorder, with the ...
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https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(17)30330-7/fulltext
The strongest association was found in MEIS1, a gene encoding a transcriptional regulator that has been implicated in the disorder, with the ...
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25
RLS (Didriksen, 2020) – Is Restless Leg Syndrome Genetic?
https://nebula.org/blog/is-restless-leg-syndrome-genetic/
Restless leg syndrome is most likely a combination of genetic and environmental factors. Several genes have been associated with developing the ...
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https://nebula.org/blog/is-restless-leg-syndrome-genetic/
Restless leg syndrome is most likely a combination of genetic and environmental factors. Several genes have been associated with developing the ...
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26
Restless in the mouse cage—A new genetic model for restless ...
https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15165
Restless legs syndrome (RLS) is a movement disorder that is characterized by an uncomfortable sensation in the legs, and the urge to move the ...
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https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15165
Restless legs syndrome (RLS) is a movement disorder that is characterized by an uncomfortable sensation in the legs, and the urge to move the ...
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27
Screening of novel restless legs syndrome–associated genes ...
https://ng.neurology.org/content/4/6/e296
As much as 60% of patients with restless legs syndrome (RLS) have a positive family history, with a heritability close to 20%. Using a cohort of ...
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https://ng.neurology.org/content/4/6/e296
As much as 60% of patients with restless legs syndrome (RLS) have a positive family history, with a heritability close to 20%. Using a cohort of ...
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28
Restless Leg Syndrome Is Underdiagnosed in Hereditary ...
https://www.mdpi.com/2077-0383/10/9/1993
Being an autosomal dominant inherited disease, men and women are equally affected by HHT. In this study, more female patients answered the survey. In general, ...
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https://www.mdpi.com/2077-0383/10/9/1993
Being an autosomal dominant inherited disease, men and women are equally affected by HHT. In this study, more female patients answered the survey. In general, ...
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29
Genetic basis for the restless legs syndrome - Ingenta Connect
https://www.ingentaconnect.com/content/10.1691/pn.20180003
It is now clear that RLS has a strong genetic component. Recent studies have identified a number of genes, including variants of PTPRD, MEIS1, ...
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https://www.ingentaconnect.com/content/10.1691/pn.20180003
It is now clear that RLS has a strong genetic component. Recent studies have identified a number of genes, including variants of PTPRD, MEIS1, ...
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30
Restless legs syndrome and related disorders - Mount Sinai
https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders
People with RLS often have a family history of the disorder. There are at least six genetic factors that may play a part. Two of the genes are linked to ...
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https://www.mountsinai.org/health-library/report/restless-legs-syndrome-and-related-disorders
People with RLS often have a family history of the disorder. There are at least six genetic factors that may play a part. Two of the genes are linked to ...
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31
Restless Legs Syndrome - Baylor College of Medicine
https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
Therefore, this RLS is usually "genetic." Often patients do not know that other family members suffer from the same condition because the relatives usually do ...
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https://www.bcm.edu/healthcare/specialties/neurology/parkinsons-disease-and-movement-disorders/restless-legs-syndrome
Therefore, this RLS is usually "genetic." Often patients do not know that other family members suffer from the same condition because the relatives usually do ...
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32
Restless Legs Syndrome: Current Concepts about Disease ...
https://tremorjournal.org/article/10.5334/tohm.322/
Discussion: RLS is a neurologic sensorimotor disorder that involves pathology, most notably iron deficiency, in motor and sensory brain areas.
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https://tremorjournal.org/article/10.5334/tohm.322/
Discussion: RLS is a neurologic sensorimotor disorder that involves pathology, most notably iron deficiency, in motor and sensory brain areas.
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33
Restless Legs Syndrome (RLS) - MalaCards
https://www.malacards.org/card/restless_legs_syndrome
MedlinePlus Genetics: Restless legs syndrome is a neurological condition that causes an irresistible urge to move the legs. The movement is triggered by ...
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https://www.malacards.org/card/restless_legs_syndrome
MedlinePlus Genetics: Restless legs syndrome is a neurological condition that causes an irresistible urge to move the legs. The movement is triggered by ...
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34
Genetics links sleep disturbance with restless legs syndrome ...
https://www.manchester.ac.uk/discover/news/genetics-links-sleep-disturbance-with-restless-legs-syndrome-schizophrenia-and-obesity/
The strongest genetic association for insomnia symptoms fell within a gene previously linked to restless legs syndrome – a nervous system ...
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https://www.manchester.ac.uk/discover/news/genetics-links-sleep-disturbance-with-restless-legs-syndrome-schizophrenia-and-obesity/
The strongest genetic association for insomnia symptoms fell within a gene previously linked to restless legs syndrome – a nervous system ...
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35
Genome-Wide Association Study Identifies Novel Restless ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002171
Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence of up to 10% in the general population above 65 years ...
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https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002171
Restless legs syndrome (RLS) is a sensorimotor disorder with an age-dependent prevalence of up to 10% in the general population above 65 years ...
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36
Restless Legs Syndrome (RLS) - Sleep Foundation
https://www.sleepfoundation.org/restless-legs-syndrome
RLS may have a genetic component. Between 40% and 90% of patients with RLS have at least one first-degree relative (parent, sibling, or child) ...
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https://www.sleepfoundation.org/restless-legs-syndrome
RLS may have a genetic component. Between 40% and 90% of patients with RLS have at least one first-degree relative (parent, sibling, or child) ...
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37
A Genetic Risk Factor for Periodic Limb Movements in Sleep
https://www.nejm.org/doi/full/10.1056/NEJMoa072743
The restless legs syndrome (RLS) is a common neurologic disorder characterized by an irresistible urge to move the legs.
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https://www.nejm.org/doi/full/10.1056/NEJMoa072743
The restless legs syndrome (RLS) is a common neurologic disorder characterized by an irresistible urge to move the legs.
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38
New Susceptibility Genes IDed for Restless Leg Syndrome
https://sleepreviewmag.com/sleep-disorders/movement-disorders/restless-legs-syndrome/susceptibility-genes-rls/
Rouleau and his research team found genes observed to be associated with RLS that were not reported in previous genetic studies. “For instance, PPP3R1, among ...
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https://sleepreviewmag.com/sleep-disorders/movement-disorders/restless-legs-syndrome/susceptibility-genes-rls/
Rouleau and his research team found genes observed to be associated with RLS that were not reported in previous genetic studies. “For instance, PPP3R1, among ...
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39
Pathophysiology of the Restless Legs Syndrome
https://www.e-jsm.org/journal/view.php?number=30
RLS encompasses an idiopathic form of genetic or unknown origin and symptomatic forms secondary to other medical conditions. Symptomatic forms are associated ...
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https://www.e-jsm.org/journal/view.php?number=30
RLS encompasses an idiopathic form of genetic or unknown origin and symptomatic forms secondary to other medical conditions. Symptomatic forms are associated ...
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40
Restless Legs Syndrome: New Gene Clues - WebMD
https://www.webmd.com/sleep-disorders/news/20070718/restless-legs-syndrome-new-gene-clues
The gene scans show that a certain variation in the BTBD9 gene was associated restless legs syndrome and other periodic limb movements during ...
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https://www.webmd.com/sleep-disorders/news/20070718/restless-legs-syndrome-new-gene-clues
The gene scans show that a certain variation in the BTBD9 gene was associated restless legs syndrome and other periodic limb movements during ...
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41
KEGG DISEASE: Restless legs syndrome
https://www.genome.jp/entry/H01597
RLS has a high familial aggregation. To date, several loci and genetic risk factors have been identified, but no causative gene mutation has been found.
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https://www.genome.jp/entry/H01597
RLS has a high familial aggregation. To date, several loci and genetic risk factors have been identified, but no causative gene mutation has been found.
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42
restless legs syndrome 6 (postulated), BTBD9-related - FlyBase
https://flybase.org/reports/FBhh0000491.html
In genome-wide association studies (GWAS), the region of the human BTBD9 gene has been associated with restless legs syndrome; subsequent work in humans has ...
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https://flybase.org/reports/FBhh0000491.html
In genome-wide association studies (GWAS), the region of the human BTBD9 gene has been associated with restless legs syndrome; subsequent work in humans has ...
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43
Restless Legs Syndrome-associated intronic common variant ...
https://genome.cshlp.org/content/24/4/592.full.html
RLS has a heritability of ∼50% and is a complex genetic disorder. GWAS identified common genetic variants within six risk loci (Winkelmann ...
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https://genome.cshlp.org/content/24/4/592.full.html
RLS has a heritability of ∼50% and is a complex genetic disorder. GWAS identified common genetic variants within six risk loci (Winkelmann ...
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44
Restless Leg and Periodic Limb Movement Disorder: Genes ...
https://www.geneticlifehacks.com/restless-leg-and-periodic-limb-movement-disorder-genetics-and-solutions/
In 2007, genome-wide studies found that the BTBD9 and MEIS1 genes were linked with an increased risk of both restless leg syndrome and periodic limb movement ...
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https://www.geneticlifehacks.com/restless-leg-and-periodic-limb-movement-disorder-genetics-and-solutions/
In 2007, genome-wide studies found that the BTBD9 and MEIS1 genes were linked with an increased risk of both restless leg syndrome and periodic limb movement ...
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45
Study Shows Restless Leg Syndrome Traced to Genetics
https://www.voanews.com/a/a-13-2007-07-23-voa62-66564322/555118.html
It has been estimated that ten percent of people worldwide suffer from Restless Leg Syndrome. RLS is a neurological disorder that makes it difficult to sit ...
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https://www.voanews.com/a/a-13-2007-07-23-voa62-66564322/555118.html
It has been estimated that ten percent of people worldwide suffer from Restless Leg Syndrome. RLS is a neurological disorder that makes it difficult to sit ...
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46
Unraveling the Mysteries of Restless Leg Syndrome - Cureus
https://www.cureus.com/articles/41299-unraveling-the-mysteries-of-restless-leg-syndrome
Primary genes associated with idiopathic RLS include MEIS1, BTBD9, and MAP2K5/SKOR1. The other genes that are secondary to RLS include alcohol- ...
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https://www.cureus.com/articles/41299-unraveling-the-mysteries-of-restless-leg-syndrome
Primary genes associated with idiopathic RLS include MEIS1, BTBD9, and MAP2K5/SKOR1. The other genes that are secondary to RLS include alcohol- ...
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47
Restless Leg Syndrome | Michigan Medicine
https://www.uofmhealth.org/conditions-treatments/brain-neurological-conditions/restless-leg-syndrome
The cause is unknown, but there is probably a genetic component because about half of people with RLS also have a close relative with the condition. Certain ...
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https://www.uofmhealth.org/conditions-treatments/brain-neurological-conditions/restless-leg-syndrome
The cause is unknown, but there is probably a genetic component because about half of people with RLS also have a close relative with the condition. Certain ...
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48
Genetics of restless legs syndrome - LMU Munich
https://www.synergy-munich.de/publications/2016/winkelmann.html
At the outset of genetic studies in restless legs syndrome (RLS), the disorder was assumed to be a classical monogenic disorder that runs in ...
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https://www.synergy-munich.de/publications/2016/winkelmann.html
At the outset of genetic studies in restless legs syndrome (RLS), the disorder was assumed to be a classical monogenic disorder that runs in ...
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49
Genetics of Restless Legs Syndrome | 11 | Sha
https://www.taylorfrancis.com/chapters/edit/10.3109/9781420019575-11/genetics-restless-legs-syndrome-shaoqi-rao-juliane-winkelmann-qing-wang
Recent advances in molecular and genetic epidemiological studies of restless legs syndrome (RLS) (MIM 102300) have led to a series of important discoveries.
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https://www.taylorfrancis.com/chapters/edit/10.3109/9781420019575-11/genetics-restless-legs-syndrome-shaoqi-rao-juliane-winkelmann-qing-wang
Recent advances in molecular and genetic epidemiological studies of restless legs syndrome (RLS) (MIM 102300) have led to a series of important discoveries.
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50
Genetics of Restless Legs Syndrome (RLS) | Request PDF
https://www.researchgate.net/publication/300636086_Genetics_of_Restless_Legs_Syndrome_RLS
Genetically, RLS is a complex disorder with a heritability of up to 60 %. While linkage analyses were largely unsuccessful, genome-wide ...
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https://www.researchgate.net/publication/300636086_Genetics_of_Restless_Legs_Syndrome_RLS
Genetically, RLS is a complex disorder with a heritability of up to 60 %. While linkage analyses were largely unsuccessful, genome-wide ...
→ Check Latest Keyword Rankings ←
51
Restless legs syndrome - RCP Journals
https://www.rcpjournals.org/content/clinmedicine/16/4/379
The pathophysiology is only partially known and a genetic component together with dopaminergic and brain iron dysregulation plays an important role. Secondary ...
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https://www.rcpjournals.org/content/clinmedicine/16/4/379
The pathophysiology is only partially known and a genetic component together with dopaminergic and brain iron dysregulation plays an important role. Secondary ...
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52
How Genes Affect The Risk of Restless Leg Syndrome
https://www.xcode.life/genes-and-sleep/how-does-genetics-affect-the-risk-of-restless-leg-syndrome/
MEIS1 and RLS · Restless Leg Syndrome is a neurologic and sleep-related movement disorder characterized by an irresistible urge to move in the legs, which ...
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https://www.xcode.life/genes-and-sleep/how-does-genetics-affect-the-risk-of-restless-leg-syndrome/
MEIS1 and RLS · Restless Leg Syndrome is a neurologic and sleep-related movement disorder characterized by an irresistible urge to move in the legs, which ...
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53
New Genes Linked to Restless Legs Syndrome
https://piedmonthealthcare.com/new-genes-linked-to-restless-legs-syndrome/
A new study involving roughly 46,000 people with restless legs syndrome turned up 13 new gene variants that appear to raise the risk for the ...
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https://piedmonthealthcare.com/new-genes-linked-to-restless-legs-syndrome/
A new study involving roughly 46,000 people with restless legs syndrome turned up 13 new gene variants that appear to raise the risk for the ...
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54
Genetics of Restless Legs Syndrome - Clinical Gate
https://clinicalgate.com/genetics-of-restless-legs-syndrome/
Adequate clinical data strongly indicate that RLS has an important genetic component. However, a crucial step before undertaking any molecular ...
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https://clinicalgate.com/genetics-of-restless-legs-syndrome/
Adequate clinical data strongly indicate that RLS has an important genetic component. However, a crucial step before undertaking any molecular ...
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55
Medline ® Abstract for Reference 37 of 'Restless legs ...
https://www.uptodate.com/contents/restless-legs-syndrome-and-periodic-limb-movement-disorder-in-children/abstract/37
There is a genetic contribution to the idiopathic restless legs syndrome (iRLS). An autosomal dominant mode of inheritance is suspected, but as yet no gene ...
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https://www.uptodate.com/contents/restless-legs-syndrome-and-periodic-limb-movement-disorder-in-children/abstract/37
There is a genetic contribution to the idiopathic restless legs syndrome (iRLS). An autosomal dominant mode of inheritance is suspected, but as yet no gene ...
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56
Restless Leg Syndrome Gene Found in Flies - NBC News
https://www.nbcnews.com/id/wbna47632521
The mysterious condition restless leg syndrome may have a genetic cause, a new study in fruit flies suggests.
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https://www.nbcnews.com/id/wbna47632521
The mysterious condition restless leg syndrome may have a genetic cause, a new study in fruit flies suggests.
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57
A Clinical Primer on Restless Legs Syndrome: What We Know ...
https://www.ajmc.com/view/a09_12aug_rls_sethi
Genomic studies have established a genetic basis for primary RLS as well, and at least 42% of people with primary RLS possess a first-degree ...
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https://www.ajmc.com/view/a09_12aug_rls_sethi
Genomic studies have established a genetic basis for primary RLS as well, and at least 42% of people with primary RLS possess a first-degree ...
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58
Heme Oxygenase-1 and 2 Common Genetic Variants and ...
https://journals.lww.com/md-journal/fulltext/2015/08040/heme_oxygenase_1_and_2_common_genetic_variants_and.45.aspx
Family reports of RLS are usually consistent with an autosomal dominant pattern of inheritance, although families with recessive or non-mendelian patterns have ...
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https://journals.lww.com/md-journal/fulltext/2015/08040/heme_oxygenase_1_and_2_common_genetic_variants_and.45.aspx
Family reports of RLS are usually consistent with an autosomal dominant pattern of inheritance, although families with recessive or non-mendelian patterns have ...
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59
RLS & Kids - Restless Legs Syndrome Foundation
https://www.rls.org/understanding-rls/rls-kids
Restless legs syndrome (RLS) doesn't only affect adults. RLS is a neurological condition with a genetic component, and often times runs in families.
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https://www.rls.org/understanding-rls/rls-kids
Restless legs syndrome (RLS) doesn't only affect adults. RLS is a neurological condition with a genetic component, and often times runs in families.
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60
Genetics of restless legs syndrome: An update. - Europe PMC
https://europepmc.org/article/med/29033051
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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https://europepmc.org/article/med/29033051
A major role of genetic factors in the risk of developing restless legs syndrome (RLS) is supported by the high frequency of positive family history of RLS ...
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61
Restless legs syndrome - tellmeGen™
https://www.tellmegen.com/en/results/dna-health-testing/restless-legs-syndrome
The underlying cause is currently unknown. A genetic component has been described as more relevant especially in cases of early onset of symptoms. Research also ...
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https://www.tellmegen.com/en/results/dna-health-testing/restless-legs-syndrome
The underlying cause is currently unknown. A genetic component has been described as more relevant especially in cases of early onset of symptoms. Research also ...
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62
Next Generation Sequencing Based Comprehensive ...
https://www.researchsquare.com/article/rs-451536/v1.pdf
Restless Legs Syndrome (RLS), is a common sensorimotor of sleep ... According to genetic studies, restless legs syndrome is a disease of ...
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https://www.researchsquare.com/article/rs-451536/v1.pdf
Restless Legs Syndrome (RLS), is a common sensorimotor of sleep ... According to genetic studies, restless legs syndrome is a disease of ...
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63
Clinical and Genetic Description of a Family With a High ...
https://www.mayoclinicproceedings.org/article/S0025-6196(11)60821-5/fulltext
Three affected family members also have Parkinson disease or essential tremor. The mode of RLS inheritance is compatible with an autosomal dominant pattern. The ...
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https://www.mayoclinicproceedings.org/article/S0025-6196(11)60821-5/fulltext
Three affected family members also have Parkinson disease or essential tremor. The mode of RLS inheritance is compatible with an autosomal dominant pattern. The ...
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64
Scientists discover a possible cause for restless legs syndrome
https://www.news24.com/health24/medical/leg/news/scientists-discover-a-possible-cause-for-restless-legs-syndrome-20171023
In a large study, researchers have found gene mutations that may explain the cause of restless legs syndrome.
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https://www.news24.com/health24/medical/leg/news/scientists-discover-a-possible-cause-for-restless-legs-syndrome-20171023
In a large study, researchers have found gene mutations that may explain the cause of restless legs syndrome.
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65
Restless Legs Syndrome Guide: Causes, Symptoms and ...
https://www.drugs.com/health-guide/restless-legs-syndrome.html
Since restless legs syndrome may affect family members across generations, scientists suspect that there is some genetic (inherited) risk of ...
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https://www.drugs.com/health-guide/restless-legs-syndrome.html
Since restless legs syndrome may affect family members across generations, scientists suspect that there is some genetic (inherited) risk of ...
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66
8 Restless Legs Syndrome Triggers | Everyday Health
https://www.everydayhealth.com/sleep-disorders/restless-leg-syndrome/8-restless-legs-syndrome-triggers/
“If you have a genetic predisposition to RLS but never had symptoms until you became pregnant, your symptoms are likely to [disappear] after you ...
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https://www.everydayhealth.com/sleep-disorders/restless-leg-syndrome/8-restless-legs-syndrome-triggers/
“If you have a genetic predisposition to RLS but never had symptoms until you became pregnant, your symptoms are likely to [disappear] after you ...
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67
Restless leg syndrome caused by gene - Deccan Herald
https://www.deccanherald.com/content/253791/restless-leg-syndrome-caused-gene.html
Restless leg syndrome, which makes people to move their legs to stop unpleasant sensations, may have a genetic cause, a new study led by an ...
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https://www.deccanherald.com/content/253791/restless-leg-syndrome-caused-gene.html
Restless leg syndrome, which makes people to move their legs to stop unpleasant sensations, may have a genetic cause, a new study led by an ...
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68
Mutant flies confirm genetic link to ... - National Geographic
https://www.nationalgeographic.com/science/article/mutant-flies-confirm-genetic-link-to-restless-legs-syndrome
In humans, RLS has been linked to a lack of dopamine (a signalling chemical in the brain), and a deficiency of iron. Freeman found evidence to ...
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https://www.nationalgeographic.com/science/article/mutant-flies-confirm-genetic-link-to-restless-legs-syndrome
In humans, RLS has been linked to a lack of dopamine (a signalling chemical in the brain), and a deficiency of iron. Freeman found evidence to ...
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69
Is Restless Leg Syndrome Real? - CNN
http://www.cnn.com/HEALTH/blogs/paging.dr.gupta/2007/07/is-restless-leg-syndrome-real.html
Two studies published this week, one in the New England Journal of Medicine, identify specific genes responsible for RLS. And it may affect many ...
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http://www.cnn.com/HEALTH/blogs/paging.dr.gupta/2007/07/is-restless-leg-syndrome-real.html
Two studies published this week, one in the New England Journal of Medicine, identify specific genes responsible for RLS. And it may affect many ...
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70
restless legs syndrome Gene Set
https://maayanlab.cloud/Harmonizome/gene_set/restless+legs+syndrome/GWASdb+SNP-Disease+Associations
restless legs syndrome Gene Set ; Description, A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in ...
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https://maayanlab.cloud/Harmonizome/gene_set/restless+legs+syndrome/GWASdb+SNP-Disease+Associations
restless legs syndrome Gene Set ; Description, A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in ...
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71
Haplotype Association of the MAP2K5 Gene with ...
https://www.psychiatryinvestigation.org/m/makeCookie.php?url=/m/journal/view.php?number=810
Restless legs syndrome (RLS) is considered a genetic disease and, following a genome-wide association study conducted in 2007, the mitogen- ...
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https://www.psychiatryinvestigation.org/m/makeCookie.php?url=/m/journal/view.php?number=810
Restless legs syndrome (RLS) is considered a genetic disease and, following a genome-wide association study conducted in 2007, the mitogen- ...
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72
Restless leg syndrome may have genetic roots - The Boston Globe
http://archive.boston.com/news/nation/articles/2007/07/19/restless_leg_syndrome_may_have_genetic_roots/
ATLANTA -- Scientists have linked certain genes to restless legs syndrome, suggesting the twitching condition described as "jimmy legs" in a "Seinfeld" ...
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http://archive.boston.com/news/nation/articles/2007/07/19/restless_leg_syndrome_may_have_genetic_roots/
ATLANTA -- Scientists have linked certain genes to restless legs syndrome, suggesting the twitching condition described as "jimmy legs" in a "Seinfeld" ...
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73
Root Causes and Remedies for Restless Leg Syndrome
https://whitneysleepcenter.com/whitney-sleep-center/root-causes-and-remedies-for-restless-leg-syndrome/
While much is still unknown about what causes Restless Leg Syndrome, researchers have indicated that the causes are both environmental and ...
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https://whitneysleepcenter.com/whitney-sleep-center/root-causes-and-remedies-for-restless-leg-syndrome/
While much is still unknown about what causes Restless Leg Syndrome, researchers have indicated that the causes are both environmental and ...
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74
Restless Legs Syndrome: A Common, Underdiagnosed ...
https://www.uspharmacist.com/article/restless-legs-syndrome-a-common-underdiagnosed-disorder
Genetics: Clinical experience has shown a strong familial connection in RLS. Several loci have been reported to date, but a disease-causing ...
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https://www.uspharmacist.com/article/restless-legs-syndrome-a-common-underdiagnosed-disorder
Genetics: Clinical experience has shown a strong familial connection in RLS. Several loci have been reported to date, but a disease-causing ...
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75
Restless Leg Syndrome (RLS): What Is It and ... - WinSanTor
https://winsantor.com/restless-leg-syndrome-rls-what-is-it-and-what-are-the-symptoms/
According to Cleveland Clinic, RLS can be genetic, and 92% of patients have a relative with this disorder. Those with a genetic predisposition will usually ...
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https://winsantor.com/restless-leg-syndrome-rls-what-is-it-and-what-are-the-symptoms/
According to Cleveland Clinic, RLS can be genetic, and 92% of patients have a relative with this disorder. Those with a genetic predisposition will usually ...
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76
Treatment for restless legs syndrome focuses on relieving the ...
https://medicalxpress.com/news/2018-09-treatment-restless-legs-syndrome-focuses.html
A: Restless legs syndrome (RLS), is not always hereditary. But it does run in some families, and several genetic links have been found for RLS.
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https://medicalxpress.com/news/2018-09-treatment-restless-legs-syndrome-focuses.html
A: Restless legs syndrome (RLS), is not always hereditary. But it does run in some families, and several genetic links have been found for RLS.
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77
Restless legs syndrome - Wikipedia
https://en.wikipedia.org/wiki/Restless_legs_syndrome
DiagnosisEdit · genetic component or family history with RLS · good response to dopaminergic therapy · periodic leg movements during day or sleep · most strongly ...
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https://en.wikipedia.org/wiki/Restless_legs_syndrome
DiagnosisEdit · genetic component or family history with RLS · good response to dopaminergic therapy · periodic leg movements during day or sleep · most strongly ...
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78
What is Restless Legs Syndrome? | UC Health | Symptoms
https://www.uchealth.com/en/conditions/restless-legs-syndrome
Restless legs syndrome (RLS) is a neurological disorder that causes unpleasant sensations in the legs. Symptoms often occur during periods of inactivity, ...
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https://www.uchealth.com/en/conditions/restless-legs-syndrome
Restless legs syndrome (RLS) is a neurological disorder that causes unpleasant sensations in the legs. Symptoms often occur during periods of inactivity, ...
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79
Restless Legs Syndrome (RLS) - HelpGuide.org
https://www.helpguide.org/articles/sleep/restless-leg-syndrome-rls.htm
An imbalance of dopamine is also believed to contribute. About 60% of people with restless legs have a family member with the condition, indicating a strong ...
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https://www.helpguide.org/articles/sleep/restless-leg-syndrome-rls.htm
An imbalance of dopamine is also believed to contribute. About 60% of people with restless legs have a family member with the condition, indicating a strong ...
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80
Restless legs syndrome - The Blood Project
https://www.thebloodproject.com/wp-content/uploads/2022/06/RLS.pdf
later cases more often associated with a more severe and rapid course of the disorder32. Individual genetic risk variants for RLS remained.
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https://www.thebloodproject.com/wp-content/uploads/2022/06/RLS.pdf
later cases more often associated with a more severe and rapid course of the disorder32. Individual genetic risk variants for RLS remained.
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81
Genetic Markers of Essential Tremor in Restless Legs ...
https://www.mdsabstracts.org/abstract/genetic-markers-of-essential-tremor-in-restless-legs-syndrome-willis-ekbom-disease-in-southern-chinese-population/
Background: Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a sleep disorder characterized by an irresistible urge to move legs, ...
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https://www.mdsabstracts.org/abstract/genetic-markers-of-essential-tremor-in-restless-legs-syndrome-willis-ekbom-disease-in-southern-chinese-population/
Background: Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a sleep disorder characterized by an irresistible urge to move legs, ...
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82
How credible are the proposed theories of Restless leg ...
https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
There are well-defined genetic factors in restless leg syndrome. While the evidence for central iron deficiency is credible, the pathophysiology ...
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https://www.entvoicesnoring.com/articles/2019/11/15/how-credible-are-the-proposed-theories-of-restless-leg-syndrome-pathophysiology-discuss-and-critically-evaluate-the-evidence
There are well-defined genetic factors in restless leg syndrome. While the evidence for central iron deficiency is credible, the pathophysiology ...
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83
Susceptible genes of restless legs syndrome in migraine
https://journals.sagepub.com/doi/10.1177/0333102415620907
Restless legs syndrome (RLS) is a disease that is characterized by an imperative urge to move the legs. RLS mostly affects individuals at night ...
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https://journals.sagepub.com/doi/10.1177/0333102415620907
Restless legs syndrome (RLS) is a disease that is characterized by an imperative urge to move the legs. RLS mostly affects individuals at night ...
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84
Restless Legs Syndrome: Detection and Management ... - AAFP
https://www.aafp.org/pubs/afp/issues/2000/0701/p108.html
Primary RLS likely has a genetic origin. Secondary causes of RLS include iron deficiency, neurologic lesions, pregnancy and uremia. RLS also may ...
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https://www.aafp.org/pubs/afp/issues/2000/0701/p108.html
Primary RLS likely has a genetic origin. Secondary causes of RLS include iron deficiency, neurologic lesions, pregnancy and uremia. RLS also may ...
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85
Restless legs syndrome: Causes, treatments, and home ...
https://www.medicalnewstoday.com/articles/7882
A secondary disorder is caused by another disease or condition. Secondary RLS usually starts after the age of 45 years, and it does not tend to be hereditary.
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https://www.medicalnewstoday.com/articles/7882
A secondary disorder is caused by another disease or condition. Secondary RLS usually starts after the age of 45 years, and it does not tend to be hereditary.
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86
Restless Leg Syndrome Gene Found in Flies | Live Science
https://www.livescience.com/20666-restless-leg-gene-flies.html
The mysterious condition restless leg syndrome may have a genetic cause, a new study in fruit flies suggests. Researchers messed with a gene ...
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https://www.livescience.com/20666-restless-leg-gene-flies.html
The mysterious condition restless leg syndrome may have a genetic cause, a new study in fruit flies suggests. Researchers messed with a gene ...
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87
Restless leg syndrome ‘may be hereditary&rsquo
https://www.thehindu.com/sci-tech/health/medicine-and-research/restless-leg-syndrome-may-be-hereditary/article2229958.ece
Restless leg syndrome may be hereditary, say scientists who claim to have discovered two faulty genes that cause the annoying condition.
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https://www.thehindu.com/sci-tech/health/medicine-and-research/restless-leg-syndrome-may-be-hereditary/article2229958.ece
Restless leg syndrome may be hereditary, say scientists who claim to have discovered two faulty genes that cause the annoying condition.
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88
Researchers Suspect a Novel Gene Is Causing Restless Legs ...
https://www.newswise.com/articles/researchers-suspect-a-novel-gene-is-causing-restless-legs-syndrome-in-a-large-family
Restless legs syndrome affects between 5 and 11 percent of the population in North America and Europe, says Dr. Lin. The cause may be a number ...
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https://www.newswise.com/articles/researchers-suspect-a-novel-gene-is-causing-restless-legs-syndrome-in-a-large-family
Restless legs syndrome affects between 5 and 11 percent of the population in North America and Europe, says Dr. Lin. The cause may be a number ...
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89
Restless Leg Syndrome and Parkinson's Disease | APDA
https://www.apdaparkinson.org/article/restless-leg-syndrome/
Although the cause of RLS in many people remains unknown, about half of people with RLS have a family history of the condition. Despite this, no specific gene ...
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https://www.apdaparkinson.org/article/restless-leg-syndrome/
Although the cause of RLS in many people remains unknown, about half of people with RLS have a family history of the condition. Despite this, no specific gene ...
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90
Restless Legs Syndrome Appears to Occur Within Families
https://www.disabled-world.com/health/neurology/sleepdisorders/restlesslegsyndrome/rls-families.php
Restless legs syndrome appears to aggregate in families, and the siblings of those who are severely affected appear to have an increased risk of ...
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https://www.disabled-world.com/health/neurology/sleepdisorders/restlesslegsyndrome/rls-families.php
Restless legs syndrome appears to aggregate in families, and the siblings of those who are severely affected appear to have an increased risk of ...
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91
Mutant flies confirm genetic link to restless legs syndrome
https://www.discovermagazine.com/planet-earth/mutant-flies-confirm-genetic-link-to-restless-legs-syndrome
Freeman has gone some way to solving that mystery, and cementing BTBD9's connection with RLS, by studying fruit flies. Flies also have a version ...
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https://www.discovermagazine.com/planet-earth/mutant-flies-confirm-genetic-link-to-restless-legs-syndrome
Freeman has gone some way to solving that mystery, and cementing BTBD9's connection with RLS, by studying fruit flies. Flies also have a version ...
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92
A potential role for zinc in restless legs syndrome - Penn State
https://pennstate.pure.elsevier.com/en/publications/a-potential-role-for-zinc-in-restless-legs-syndrome
Conclusion: We show for the first time that serum and brain levels of zinc are elevated in RLS. Further, we confirm the BTBD9 genetic risk ...
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https://pennstate.pure.elsevier.com/en/publications/a-potential-role-for-zinc-in-restless-legs-syndrome
Conclusion: We show for the first time that serum and brain levels of zinc are elevated in RLS. Further, we confirm the BTBD9 genetic risk ...
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93
Restless Leg Syndrome | AHC Media: Continuing Medical…
https://www.reliasmedia.com/articles/67276-restless-leg-syndrome
The finding of near-complete concordance of monozygotic twins for RLS symptoms confirms prior studies suggesting that familial RLS is a genetic disorder.
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https://www.reliasmedia.com/articles/67276-restless-leg-syndrome
The finding of near-complete concordance of monozygotic twins for RLS symptoms confirms prior studies suggesting that familial RLS is a genetic disorder.
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