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1 Regulation of skeletal muscle stem cells by fibroblast growth ...
https://pubmed.ncbi.nlm.nih.gov/28249356/
Fibroblast growth factors (FGFs) are essential for self-renewal of skeletal muscle stem cells (satellite cells) and required for maintenance and repair of ...
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2 Fibroblast Growth Factor Promotes Recruitment of Skeletal ...
https://journals.sagepub.com/doi/10.1177/002215549904700104
The FGF-promoted increase in satellite cells was observed in the present fiber study by the second day in culture. It is noteworthy that, in another study of ...
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3 A role for FGF-6 in skeletal muscle regeneration - Genes Dev
http://genesdev.cshlp.org/content/11/16/2040
We conclude that FGF-6 is a critical component of the muscle regeneration machinery in mammals, possibly by stimulating or activating satellite cells.
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4 Extrinsic regulation of satellite cell specification
https://stemcellres.biomedcentral.com/articles/10.1186/scrt27
(b) Schematic of the different environmental cues influencing a satellite cell in its niche. FGF, fibroblast growth factor, HGF, ...
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5 Satellite cells from dystrophic (mdx) mouse muscle are ...
https://www.sciencedirect.com/science/article/pii/S0301468111604775
Total cell number and muscle-fiber formation are stimulated by bovine fibroblast growth factor (FGF). At low FGF levels (0.02–0.20 ng/ml) control satellite ...
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6 Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated ...
https://www.frontiersin.org/articles/10.3389/fnagi.2015.00085/full
Skeletal muscle satellite cells (SCs) are Pax7+ myogenic stem cells that ... In particular, the role of the fibroblast growth factor (FGF) ...
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7 Stem cell activation in skeletal muscle regeneration
https://link.springer.com/article/10.1007/s00018-014-1819-5
FGF can also induce the activation of satellite cells by enhancing the G1-S transition through ERK signaling pathway.
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8 Publications | Olwin Lab | University of Colorado Boulder
https://www.colorado.edu/lab/olwin/publications
Loss of niche-satellite cell interactions in syndecan-3 null mice alters muscle ... Loss of FGF receptor 1 signaling reduces skeletal muscle mass and ...
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9 Trenbolone alters the responsiveness of skeletal muscle ...
https://experts.arizona.edu/en/publications/trenbolone-alters-the-responsiveness-of-skeletal-muscle-satellite
The potential role of satellite cells in mediating the effect of trenbolone ... the stimulatory response of these cells to fibroblast growth factor (FGF) or ...
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10 Satellite Cells and the Muscle Stem Cell Niche
https://journals.physiology.org/doi/full/10.1152/physrev.00043.2011
As skeletal muscle stem cells, satellite cells play an indispensible role in this ... Upon injury, released fibroblast growth factor (FGF) and hepatocyte ...
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11 An ageing decline | Nature Reviews Molecular Cell Biology
https://www.nature.com/articles/nrm3464
Satellite cells have the capacity to self-renew and function as a stem ... FGF ligands are potent stimulators of satellite cell mitogenic ...
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12 Effect of Fibroblast Growth Factor 2 on Extraocular Muscle ...
https://iovs.arvojournals.org/article.aspx?articleid=2776495
FGF signaling mediates muscle satellite cell activation and proliferation during development and in response to injury in limb skeletal muscle.31–36 The role of ...
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13 The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis ...
https://openaccesspub.org/jsm/article/1309
Aging mammalian skeletal muscle satellite cells (MuSCs) undergo a decline of stem cell/progenitor cell proliferative and regenerative capacity, ...
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14 Growth Factors for Skeletal Muscle Tissue Engineering
https://www.karger.com/Article/Fulltext/444671
These satellite cells are not activated during embryonic ... The stimulatory effect of FGF on satellite cell proliferation has been shown to ...
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15 Sulfs are regulators of growth factor signaling for satellite cell ...
https://www.bumc.bu.edu/pulmonary/files/PDFs/Faculty/ai1.pdf
Previous studies have shown that FGFs and HGF not only trigger the activation and promote the proliferation of satellite cells, but also block myogenic.
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16 Cripto regulates skeletal muscle regeneration and modulates ...
https://www.pnas.org/doi/10.1073/pnas.1204017109
Skeletal muscle regeneration mainly depends on satellite cells, ... Basic FGF was used as a positive control; n = 7 independent experiments; **P = 0.05.
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17 Effects of FGF2 on satellite cell activation and proliferation....
https://www.researchgate.net/figure/Effects-of-FGF2-on-satellite-cell-activation-and-proliferation-Freshly-isolated-FDB_fig9_260396853
... Fibroblast growth factor (FGF) is one such factor. Its action via transient receptor potential channels (TRPC) leads to the translocation of nuclear factor ...
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18 Reduced Mobility of Fibroblast Growth Factor (FGF)
https://journals.asm.org/doi/10.1128/MCB.23.17.6037-6048.2003
Satellite cell-derived myoblasts and bone marrow-derived myogenic precursor cells (14) can migrate extensively and cross the basal lamina of myofibers (24, 50).
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19 International Journal of Neuroscience - Taylor & Francis Online
https://www.tandfonline.com/doi/full/10.1080/15569520701502716
Furthermore, the state of satellite cell reaction and changes in the FGF-2/S100ß immunoreactivity were analyzed after axotomy of rat sciatic nerve. Scattered ...
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20 Fibroblast growth factor 2-stimulated proliferation is lower in ...
https://libres.uncg.edu/ir/asu/f/Zwetsloot_Kevin_2009_Fibrolast_growth.pdf
Muscle precursor cells (MPCs), or satellite cells, are adult skeletal muscle stem cells that are ... basic FGF or bFGF, is a polypeptide growth factor that.
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21 Trenbolone Alters the Responsiveness of Skeletal Muscle ...
https://academic.oup.com/endo/article/124/5/2110/2532015
The potential role of satellite cells in mediating the effect of trenbolone ... the stimulatory response of these cells to fibroblast growth factor (FGF) or ...
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22 Skeletal muscle satellite cell proliferation | 32 Publications
https://typeset.io/topics/skeletal-muscle-satellite-cell-proliferation-dogw0ill
TL;DR: By altering the concentrations of TGF‐beta, FGF, and IGF‐I, satellite cells can be induced to proliferate, differentiate, or to remain quiescent.
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23 FGF2 activates TRPC and Ca2+ signaling ... - ReadCube
https://www.readcube.com/articles/10.3389/fphys.2014.00038
Inresponse to an injury, the quiescent satellite cell is activated by soluble factors, includingFGFs released from injured myofibers.
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24 Muscle Regeneration: Cellular and Molecular Events - In Vivo
https://iv.iiarjournals.org/content/23/5/779
The high amounts of FGFs, which are released within the short period of inflammation after tissue disruption, may induce satellite cells to proliferate and ...
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25 Sulf1A and HGF regulate satellite-cell growth
https://journals.biologists.com/jcs/article/123/11/1873/31075/Sulf1A-and-HGF-regulate-satellite-cell-growth
For example, fibroblast growth factor (FGF) signal transduction is ... Both HGF and FGFs are known to regulate satellite-cell activation and ...
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26 Proliferative Dynamics and the Role of FGF2 During ...
https://europepmc.org/article/med/26052220
Myogenic precursors in adult skeletal muscle (satellite cells) are mitotically quiescent but can proliferate in response to a variety of stresses including ...
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27 Mechanism of satellite cell regulation by myokines - J-Stage
https://www.jstage.jst.go.jp/article/jpfsm/6/5/6_311/_pdf/-char/en
Abstract Skeletal muscle stem cells, known as satellite cells, ... response to FGF-2, are required for satellite cells to enter.
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28 Molecular Regulation of Muscle Stem Cell Number - Grantome
https://grantome.com/grant/NIH/R56-AR073805-01A1
Applying transcriptomics to this mouse model, we have identified FGF signaling, i.e. FGF6, as a physiologically relevant pathway regulating satellite cell ...
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29 Efficient myoblast expansion for regenerative medicine use
https://www.spandidos-publications.com/10.3892/ijmm.2014.1763
Satellite cells remain in a quiescent state in uninjured tissue. ... The effectiveness of EGF, FGF and PDGF growth factors in enhancing ...
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30 The Development of Skeletal Muscle in Young Horses
https://opencommons.uconn.edu/srhonors_theses/419/
Both IL-6 and TNF-α decreased proliferation of satellite cells. ... and FGF-2, but differentiation was decreased in the presence of FGF-2 ...
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31 Extrinsic Regulation of Satellite Cell Function and Muscle ...
https://www.walshmedicalmedia.com/open-access/extrinsic-regulation-of-satellite-cell-function-and-muscle-regeneration-capacity-during-aging-2157-7633.S11-001.pdf
Keywords: Muscle regeneration; Satellite cells; Skeletal muscle stem ... FGFs are well-characterized mitogens that induce satellite cells.
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32 The aged niche disrupts muscle stem cell quiescence
https://dash.harvard.edu/bitstream/handle/1/11180414/3605795.pdf?sequence%3D1
Increasing FGF signalling in aged satellite cells under homeostatic conditions by removing spry1, results in the loss of quiescence, satellite cell ...
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33 Functional Overload Enhances Satellite Cell Properties in ...
https://www.hindawi.com/journals/sci/2016/7619418/
Skeletal-muscle-derived stem cells, termed satellite cells, ... with 10% fetal bovine serum (FBS), 20 ng/mL basic fibroblast growth factor (FGF), ...
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34 The p38α/β MAPK functions as a molecular switch to activate ...
https://rupress.org/jcb/article/169/1/105/51796/The-p38-MAPK-functions-as-a-molecular-switch-to
Activation of satellite cells and p38α/β MAPKs occurs concomitantly, ... Quiescent satellite cells express c-met (the HGF receptor), FGF receptors 1 and 4, ...
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35 Synthetic matrix enhances transplanted satellite cell ... - Science
https://www.science.org/doi/10.1126/sciadv.aar4008
Muscle satellite cells (MuSCs) play a central role in muscle regeneration, ... supplementation of FGF-2 for 6 days and then in differentiation media for an ...
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36 Myosatellite cell - Wikipedia
https://en.wikipedia.org/wiki/Myosatellite_cell
Myosatellite cells, also known as satellite cells, muscle stem cells or MuSCs, ... (FGF) enhance satellite cell proliferation rate following activation.
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37 Fibroblast growth factor-23 induces cellular senescence in ...
https://agris.fao.org/agris-search/search.do?recordID=US201600195969
The MSCs expressed FGF receptors (1 through 4) and angiotensin-II type 1 receptor, but no traces of the Klotho gene were detected. MSCs and satellite cells ...
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38 ZIPORA YABLONKA-REUVENI – Biological Structure - UW Sites
https://sites.uw.edu/biostr/people/faculty/zipora-yablonka-reuveni/
The role of FGF-FGFR system in regulating satellite cells. The role of Klotho genes in the balance between myogenicity and adiposity of skeletal muscle.
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39 invited review - Paulo Gentil
https://paulogentil.com/pdf/Myogenic%20satellite%20cells%20-%20physiology%20to%20molecular%20biology.pdf
skeletal muscle and are referred to as satellite cells. After their initial identification ... of the FGF family on satellite cell proliferation in culture.
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40 Smad4 restricts differentiation to promote expansion of ... - eLife
https://elifesciences.org/articles/19484
Loss of Smad4 expression in aged satellite cells and myogenic ... we then examined the expression levels of pertinent FGF ligands and ...
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41 A Serum-Free Medium That Supports the Growth of Cultured ...
https://www.jstor.org/stable/4295843
cultures of rat skeletal muscle satellite cells for up to 4 d. The medium consists of a mixture of ... (FGF), bovine serum albumin-linoleic acid, epidermal.
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42 Molecular aging and rejuvenation of human muscle stem cells
https://www.embopress.org/doi/10.1002/emmm.200900045
We find that satellite cells are maintained in aged human skeletal muscle, ... effector of MAPK) were induced by FGF-2 and reduced by MEK inhibitor, ...
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43 regenerative potential of skeletal muscle stem cells
https://www.jci.org/articles/view/40373
Regeneration mainly depends upon satellite cells, myogenic progenitors localized ... cells, are involved in SC activation, including HGF (36), FGF (37), ...
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44 Bradley Olwin | Colorado PROFILES
https://profiles.ucdenver.edu/display/224622
The regenerating skeletal muscle niche drives satellite cell return to quiescence. ... Loss of FGF receptor 1 signaling reduces skeletal muscle mass and ...
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45 Roles and Regulation of Satellite Cells in Skeletal Muscle ...
https://pdxscholar.library.pdx.edu/cgi/viewcontent.cgi?article=2306&context=honorstheses
understanding of satellite cell-mediated regeneration and the related ... Lastly to note, regarding angiogenesis, FGF-2 and FGF-6 are ...
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46 THE REQUIREMENT FOR β1-INTEGRIN IN THE MUSCLE ...
https://jscholarship.library.jhu.edu/handle/1774.2/39558?show=full
The adult muscle stem cell, i.e. the satellite cell (SC), is maintained in a ... growth factor (FGF), leads to SC activation for muscle regeneration.
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47 Satellite cell‐specific ablation of Cdon impairs integrin ...
https://search.proquest.com/openview/a2570300aa8f7dae7f1c224757cfbb78/1?pq-origsite=gscholar&cbl=4370305
Satellite cell‐specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration. Abstract. Background. Perturbation in cell ...
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48 Effects of Vitamin D on Satellite Cells: A Systematic Review of ...
https://www.mdpi.com/2072-6643/14/21/4558/pdf
Satellite cells are skeletal muscle stem cells that play a pivotal ... protein 4 (Bmp4) and fibroblast growth factor-2 (Fgf-2), markers that ...
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49 Dysregulated cell signalling and reduced satellite ... - bioRxiv
https://www.biorxiv.org/content/10.1101/761023v1.full
Satellite cells on isolated muscle fibres showed spontaneous in vivo satellite ... A number of studies have shown that both the Wnt and FGF ...
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50 Initial Observations on the Growth Factor Regulation of Equine ...
http://www.bio.unipd.it/~bam/PDF/5-1/Greene.pdf
on equine muscle satellite cell proliferation and differentiation in vitro. Increasing concentra- ... Key words: horse, satellite cells, IGF-I, FGF, TGF-B.
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51 The Makarenkova Lab - Scripps Research
https://www.scripps.edu/makarenkova/research.html
Satellite cells are muscle progenitor cells, which reside in skeletal muscle and ... Our previous studies have shown that members of the (FGF) family are ...
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52 Satellite Cell Isolation Kit, mouse - Miltenyi Biotec
https://www.miltenyibiotec.com/BE-en/products/satellite-cell-isolation-kit-mouse.html
The Satellite Cell Isolation Kit, mouse has been developed for the ... 2.5 ng/mL human FGF-2, 100 U/mL penicillin/ 100 U/mL streptomycin) for six days.
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53 The Changes of Muscle FGF-6 Expression at Different Time ...
https://www.mona.uwi.edu/fms/wimj/system/files/article_pdfs/yu_et_al-muscle_fgf-6_expression.pdf
Objective: To investigate the changes of fibroblast growth factor (FGF)-6 expression in the ... satellite cells, which are situated between the basal lamina.
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54 The Role of Fibroblast Growth Factor (FGF) Signaling ... - MDPI
https://mdpi-res.com/d_attachment/cells/cells-10-03242/article_deploy/cells-10-03242-v2.pdf?version=1637720220
Keywords: FGF; FGFR; tissue repair; tissue regeneration; cell proliferation; ... ated by stem cells known as satellite cells, which are also required for ...
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55 Abstract 13828: Fibroblast Growth Factor-23 Induces Cellular ...
https://www.ahajournals.org/doi/10.1161/circ.132.suppl_3.13828
Introduction: Mesenchymal stem cells (MSCs) in skeletal muscle represent a distinct cell population from satellite cells (StCs), ...
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56 An FGF-2 signaling pathway that is activated in aged skeletal ...
https://www.ebi.ac.uk/pride/archive/projects/PXD020575
Deep proteome of aging skeletal muscles reveals Smoc2 as a modulator of satellite cell regenerative capacity. 2019-09-27.
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57 How Do Muscles Grow? - University of New Mexico
https://www.unm.edu/~lkravitz/Article%20folder/musclesgrowLK.html
Trauma to the Muscle: Activating The Satellite Cells ... The role of FGF may be in the revascularization (forming new blood capillaries) process during ...
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58 (PDF) Regulation of skeletal muscle satellite cell proliferation ...
https://www.academia.edu/80046284/Regulation_of_skeletal_muscle_satellite_cell_proliferation_by_bovine_pituitary_fibroblast_growth_factor
By altering the concentrations of TGF-beta, FGF, and IGF-I, satellite cells can be induced to proliferate, differen- tiate, or to remain quiescent.
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59 Human Recombinant FGF-acidic - STEMCELL Technologies
https://www.stemcell.com/human-recombinant-fgf-acidic.html
FGF-acidic is a potent activator of DNA synthesis, cell proliferation, and chemotaxis and has roles during development, regeneration, and angiogenesis.
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60 The Role of Satellite Cells and FAPs in Muscle Regeneration
https://www.youtube.com/watch?v=IMixU0Z8Un4
May 22, 2015
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61 Skeletal Muscle Repair and Regeneration
https://books.google.com/books?id=3arwHDny8sEC&pg=PA121&lpg=PA121&dq=fgf+satellite+cells&source=bl&ots=237zKQooi0&sig=ACfU3U1PhJl24tkpOd05dN9yhRkSHoepeQ&hl=en&sa=X&ved=2ahUKEwjs9J7ur737AhVgJUQIHeH8BDYQ6AF6BQjbAhAD
2.1.4 Does FGF promote satellite cell activation? There has been a continuous debate as to whether FGF is involved in activation of satellite cells or, ...
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62 Skeletal Muscle Damage and Repair - Page 83 - Google Books Result
https://books.google.com/books?id=ueMh1x7kFjsC&pg=PA83&lpg=PA83&dq=fgf+satellite+cells&source=bl&ots=wAJhAuh_Iw&sig=ACfU3U0wd0dGfLyZ419BRYIEUvML2lNEkw&hl=en&sa=X&ved=2ahUKEwjs9J7ur737AhVgJUQIHeH8BDYQ6AF6BQjdAhAD
Figure 6.4 Growth factors and cytokines mediate the regulation of myogenic satellite cells . FGF : fibroblast growth factor ; IGF : insulin - like growth ...
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63 FGF-acidic, Human - GenScript
https://www.genscript.com/protein/Z02921-FGF_acidic_Human.html
ED50 < 0.3 ng/ml, measured by a cell proliferation assay of 3T3 Cells, corresponding to a specific activity of > 3.3 × 106 IU/mg in the presence of 10.0 μg/ml ...
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64 Revive: Short Films on Stem Cells - EuroStemCell
https://www.eurostemcell.org/revive-short-films-stem-cells
Skeletal Muscles To understand how the muscle stem cells (satellite cells) repair the muscle fibers the Institut Pasteur and the LabExRevive takes us inside ...
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65 Fibroblast Growth Factor - What is it? - StemCultures
https://stemcultures.com/fibroblast-growth-factor-what-is-it/
At the very early embryonic stages, we now know from culturing embryonic stem cells, FGF2 is essential for maintaining the stem cell state, ...
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66 Sturkie's Avian Physiology - Page 551 - Google Books Result
https://books.google.com/books?id=Si4MEAAAQBAJ&pg=RA1-PA551&lpg=RA1-PA551&dq=fgf+satellite+cells&source=bl&ots=Ks6dId20CB&sig=ACfU3U0F9L4IdJ_Q-Pb9zao-1upm0Q6Ndw&hl=en&sa=X&ved=2ahUKEwjs9J7ur737AhVgJUQIHeH8BDYQ6AF6BQjXAhAD
Satellite cells were first isolated and cultured by Bischoff (1974) from the ... Satellite cells express various types of FGF receptors, mainly 1 and 4, ...
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67 Skeletal Muscle Plasticity in Health and Disease: From Genes ...
https://books.google.com/books?id=PhAk0uvRqXIC&pg=PA149&lpg=PA149&dq=fgf+satellite+cells&source=bl&ots=hhqPziv6Qb&sig=ACfU3U0yTDlLelqbnl835KX7TCHaixcHXw&hl=en&sa=X&ved=2ahUKEwjs9J7ur737AhVgJUQIHeH8BDYQ6AF6BQjZAhAD
Moreover, activated satellite cells in regenerating mdx muscle coexpress HGF and ... 9.2 FGFs Fibroblast growth factor (FGF) was first identified in bovine ...
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68 Pathobiology of Human Disease: A Dynamic Encyclopedia of ...
https://books.google.com/books?id=uQB0AwAAQBAJ&pg=PA571&lpg=PA571&dq=fgf+satellite+cells&source=bl&ots=0o_1E69syB&sig=ACfU3U1L86v0fJNEjuT0jDHg8cB2lcr5Mw&hl=en&sa=X&ved=2ahUKEwjs9J7ur737AhVgJUQIHeH8BDYQ6AF6BQjcAhAD
Since FGF is a potent activator of satellite cells, the expression of Spry1 in quiescent cells buffers the response to FGF in their environment.
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